Effect of exercise training on endogenous carbon monoxide exhalation in humans.
| Project/Area Number |
23500779
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Sports science
|
|---|
| Research Institution | Toyohashi University of Technology |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
SAITO Yoshihiro 豊橋技術科学大学, 大学院・工学研究科, 准教授 (00303701)
SAKUMA Kunihiro 豊橋技術科学大学, 工学部, 准教授 (60291176)
NIWAYAMA Masatsugu 静岡大学, 工学部, 准教授 (40334958)
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
|---|
| Keywords | ガス状伝達物質 / 一酸化炭素 / 硫化水素 / ヘムオキシゲナーゼ / パルスオキシメータ / カーボライザー / 呼気ガス / 一酸化窒素 / カルボキシヘモグロビン / heme oxygenase / 運動 / トレーニング |
|---|
| Research Abstract |
In the present study we aimed to measure exhaled carbon monoxide (CO) during and after exercise in smokers and non-smokers. We could observe that exhaled carbon oxide increased relatve to exercise intensity and decreased rapidly after exercise. The amounts of CO exhalation in smokers were significantly larger than those of non-smokers. We also attempted to develop a prototype model to estimate carboxyhemoglobin concentrations (COHb) transcutaneously in the blood using multi-wavelength optical sources. The COHb could be continuously measured by a prototype model, however problems relevant to the stability and resolution still remained. Furthermore, we also measured the expression of heme oxygenase-1 and -2 which are the enzymes producing CO in mice, and found that the expression of these enzymes in the skeletal muscles increased with acute exercise and strength training.
|
Report
(4 results)
Research Products
(46 results)
