Exhaustive risk evaluation of trans-fatty acid and glycidol fatty acid esther
Project/Area Number |
23500964
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Eating habits, studies on eating habits
|
Research Institution | University of Shizuoka |
Principal Investigator |
MASUDA Shuichi 静岡県立大学, 食品栄養科学部, 准教授 (40336657)
|
Project Period (FY) |
2011 – 2013
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | トランス脂肪酸 / グリシドール脂肪酸エステル / 遺伝毒性 / 加熱調理 / 食肉 / 食用油 / コメットアッセイ / 小核試験 |
Research Abstract |
Trans-fatty acid (TFA) was detected in some dietary oils (0.3-1.93g/100g). However, the concentration of TFA was decreased by heating. Though glycidol fatty acid ester (GE) was determined in oils, the levelof GE was also decreased by heating. Treatment of GE showed the siginificantly genotoxcities (reverse mutation, DNA damages and the frequency of micronuclei) in Ames test(TA100), COMET assay and micronuclei test compared to non-treated groups. The concentration of GE in comminuted pig meat heated with charcoal firewas very high (195g/100g meat). From these results, it is demonstrated that we are habitually exposed to TFA and GE that have an influence on the health of human from daily foods. It is important to estimate the risk of these chemicals to human.
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Report
(4 results)
Research Products
(39 results)
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[Journal Article] Genotoxicity of multi-walled carbon nanotubes in both in vitro and in vivo assay systems2013
Author(s)
Kato T, Totsuka Y, Ishino K, Matsumoto Y, Tada Y, Nakae D, Goto S, Masuda S, Ogo S, Kawanishi M, Yagi T, Matsuda T, Watanabe M, Wakabayashi K
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Journal Title
Nanotoxicology
Volume: 7(4)
Pages: 452-461
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[Journal Article] [Residual pesticide concentrations after processing various types of tea and tea infusions2013
Author(s)
Kondo T, Watanabe A, Shitara H, Kaburagi Y, Shibata M, Kanda N, Kurokawa C, Inoue Y, Miyazaki M, Togawa M, Ozawa A, Uchiyama T, Koizumi Y, Nakamura Y, Masuda S
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Journal Title
Shokuhin Eiseigaku Zasshi
Volume: 54
Pages: 259-264
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Peer Reviewed
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[Journal Article] Solophenols B-D and solomonin: new prenylated polyphenols isolated from propolis collected from the Solomon Islands and their antibacterial activity2012
Author(s)
Inui S, Hosoya T, Shimamura Y, Masuda S, Ogawa T, Kobayashi H, Shirafuji K, Moli RT, Kozone I, Shin-ya K, Kumazawa S
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Journal Title
J. Agric. Food Chem
Volume: 60(47)
Pages: 11765-70
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[Journal Article] Acrylamide genotoxicity in young versus adult gpt delta male rats2011
Author(s)
Koyama N, Yasui M, Kimura A, Takami S, Suzuki T, Masumura K, Nohmi T, Masuda S, Kinae N, Matsuda T, Imai T, Honma M
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Journal Title
Mutagenesis
Volume: 26(4)
Pages: 545-549
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[Journal Article] Acrylamide genotoxicity in young versus adult gpt delta male rats.2011
Author(s)
Koyama N, Yasui M, Kimura A, Takami S, Suzuki T, Masumura K, Nohmi T, Masuda S, Kinae N, Matsuda T, Imai T, Honma M
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Journal Title
Mutagenesis
Volume: 26
Pages: 545-549
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Peer Reviewed
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[Book] 株式会社 南江堂2011
Author(s)
増田修一他15名 (那須正夫、和田啓爾 編)
Total Pages
349
Publisher
食品衛生学「食の安全」の科学
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[Book] 茶論2011
Author(s)
増田修一、島村裕子、下位香代子、木苗直秀
Total Pages
29
Publisher
NPO法人 日本茶インストラクター協会
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[Book] 株式会社 講談社2011
Author(s)
増田修一他36名(日本香辛料学会 編)
Total Pages
221
Publisher
スパイスなんでも小事典
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