| Project/Area Number |
23510068
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Risk sciences of radiation/Chemicals
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| Research Institution | Kanazawa Medical University |
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Principal Investigator |
KOJIMA Masami 金沢医科大学, 看護学部, 教授 (40183339)
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| Co-Investigator(Renkei-kenkyūsha) |
OKUNO Tsutomu 独立行政法人 労働安全衛生総合研究所, リスク管理研究グループ, 上席研究員 (90332395)
SUZUKI Yukihisa 首都大学東京, 都市教養学部, 准教授 (30336515)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2013: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
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| Keywords | 熱白内障 / 赤外線 / 眼内熱伝達 / 赤外線A波 / 赤外線B波 / 赤外線C波 / 房水対流 / 感温カプセル / 眼内熱輸送 / 眼球モデル / 眼内での熱輸送 / 赤外線波長特異性 / 赤外線Ａ波 / 熱障害 / 虹彩 / 白内障 / 家兎 / 網膜の熱障害 |
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| Research Abstract |
The pathogenic mechanism of infrared cataract differed by infrared wavelengths. The ocular lesions by infrared (IR) A (808 nm) exposure occurred around the pigmented part in the ocular tissue. In contrast, those by the IR-B and C exposure were mainly corneal damages.
The intraocular thermal transportation analysis elucidates that IR-A energy is absorbed by the iris, generating heat-induced disorders, and its heat reaches the crystalline lens and causes cataract. In contrast, the thermal transport route in the IR-B exposed eye was observed to rise from the right under the cornea and the convection descended to the iris or the crystalline lens side.
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