| Project/Area Number |
23510069
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Risk sciences of radiation/Chemicals
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| Research Institution | Tokushima Bunri University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
OYOSHI Takanori 静岡大学, 理学部, 講師 (80406529)
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| Project Period (FY) |
2011-04-28 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 酸化 / クラスター損傷 / DNAポリメラーゼ / 連続クラスター損傷 / グアニン酸化損傷 |
|---|
| Outline of Final Research Achievements |
In this research, the 6mer oligomer containing Oz was ligated with 13mer and 11mer oligomers and the complimentary 30mer oligomer, and then the 30mer oligomer containing OzOz was prepared. Using DNA polymerase alpha, beta, zeta, eta, kappa, Klenow fragment or REV1, primer elongation was performed.
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