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Neuronal mechanisms underlying representation of upcoming reward outcomes in macaque temporal cortex

Research Project

Project/Area Number 23530971
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Experimental psychology
Research InstitutionNational Institute of Advanced Industrial Science and Technology

Principal Investigator

SUGASE-MIYAMOTO Yasuko  独立行政法人産業技術総合研究所, ヒューマンライフテクノロジー研究部門, 主任研究員 (40357257)

Co-Investigator(Renkei-kenkyūsha) MATSUMOTO Narihisa  独立行政法人産業技術総合研究所, ヒューマンライフテクノロジー研究部門, 主任研究員 (00392663)
SHIDARA Munetaka  筑波大学, 人間総合科学研究科, 教授 (10357189)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords記憶 / 視覚 / 報酬 / 連合 / ニューロン / 視覚刺激 / 霊長類 / 単一ニューロン活動
Research Abstract

The importance of the perirhinal cortex for reward-related information processing has been suggested. To examine whether or not neurons in this cortex represent reward information flexibly when a visual stimulus indicates either a rewarded or unrewarded outcome, we examined neuronal activity in the macaque perirhinal cortex using a conditional-association cued-reward task. The task design allowed us to study how the neuronal responses depended on the animal's prediction of whether it would or would not be rewarded. Two visual stimuli, a color stimulus followed by a pattern stimulus, were sequentially presented. Each pattern stimulus was conditionally associated with both rewarded and unrewarded outcomes depending on the preceding color stimulus. An activity depending on the upcoming reward outcomes was observed during the pattern stimulus presentation, indicating that the perirhinal cortexneurons flexibly signals the meaning of a stimulus independent of the identity of the stimulus.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (6 results)

All 2012 2011 Other

All Journal Article (2 results) Presentation (2 results) Remarks (2 results)

  • [Journal Article] Stimulus related activity during conditional associations in monkey perirhinal cortex neurons depends on upcoming reward outcome2012

    • Author(s)
      Ohyama K, Sugase-Miyamoto Y, Matsumoto N, Shidara M, Sato C
    • Journal Title

      Journal of Neuroscience

      Volume: vol. 32 (48) Pages: 17407-17419

    • NAID

      120007136849

    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Journal Article] Differential Encoding of Factors Influencing Predicted Reward Value in Monkey Rostral Anterior Cingulate Cortex2012

    • Author(s)
      Toda K, Sugase-Miyamoto Y, Mizuhiki T, Inaba K, Richmond BJ, Shidara M
    • Journal Title

      PLoS One

      Volume: Vol. 7 (1)

    • Related Report
      2013 Final Research Report
  • [Presentation] Specific neuron represents combinations of visual stimuli in area TE and reward contingency in perirhinal cortex2011

    • Author(s)
      Ohyama K, Sugase-Miamoto Y, Matsumoto N, Shidara M, Sato C
    • Organizer
      Neuroscience 2011
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2011-11-13
    • Related Report
      2013 Final Research Report
  • [Presentation] TE野ニューロンは視覚刺激の組み合わせを傍嗅皮質ニューロンは報酬情報をコードする2011

    • Author(s)
      大山薫、菅生‐宮本康子、松本有央、設楽宗孝、佐藤主税
    • Organizer
      Neuroscience 2011
    • Place of Presentation
      Washington DC, USA
    • Related Report
      2011 Research-status Report
  • [Remarks] 状況に応じて物事の意味を柔軟に認識する脳の活動を発見

    • URL

      http://www.aist.go.jp/aist_j/new_research/nr20130110/nr20130110.html

    • Related Report
      2013 Final Research Report
  • [Remarks] 状況に応じて物事の意味を柔軟に認識する脳の活動を発見

    • URL

      http://www.aist.go.jp/aist_j/new_research/nr20130110/nr20130110.html

    • Related Report
      2012 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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