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Study on Multiplex Imaging in Proton radiography

Research Project

Project/Area Number 23540350
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Particle/Nuclear/Cosmic ray/Astro physics
Research InstitutionNagaoka University of Technology (2012-2013)
National Institute of Technology, Toyama College (2011)

Principal Investigator

ASO Tsukasa  長岡技術科学大学, 工学部, 准教授 (30290737)

Co-Investigator(Renkei-kenkyūsha) SASAKI Takashi  高エネルギー加速器研究機構, 計算科学センター, 教授 (50259983)
NISHIO Teiji  国立がん研究センター, 東病院臨床開発センター, 室長 (40415526)
TAKADA Eiji  富山高等専門学校, 専攻科, 教授 (00270885)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords放射線画像 / シミュレーション / Geant4 / 粒子線治療 / 陽子線治療 / 陽子線画像 / モンテカルロ・シミュレーション / 放射線 / モンテカルロ法 / 多重画像 / ラジオグラフィ / 粒子線画像
Research Abstract

We studied about the multiplex proton radiography using a proton accelerator in a proton therapy facility. The study has been performed by using the Monte Carlo simulation based on Geant4 simulation toolkit and the analysis techniques in the High Energy Physics research. The proposed proton imaging system was investigated in terms of possibility, performance, and optimizations.
For the purpose of realizing a simple proton radiography, we utilized the range modulator to vary proton beam energy to emphasis the energy losses of different materials. We evaluated our proposed system in the image quality and the radiation dose in the target. The result shows that our system can obtain proton images with simpler and cheeper equipments than other proton imaging systems.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (37 results)

All 2014 2013 2012 2011

All Journal Article (7 results) (of which Peer Reviewed: 7 results) Presentation (30 results)

  • [Journal Article] Common platform of Monte Carlo dose calculation on universal grid interface with Geant4 based particle therapy simulation framework2014

    • Author(s)
      G Iwai, W Takase, T Aso, Y Watase, T Sasaki, T Akagi, T Yamashita, Y Maeda and T Nishio
    • Journal Title

      XVII International Conference on the Use of Computers in Radiation Therapy (ICCR 2013) IOP Publishing, Journal of Physics

      Volume: 489 Pages: 12001-12001

    • DOI

      10.1088/1742-6596/489/1/012001

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Geant4-based particle therapy simulation framework for verification of dose distributions in proton therapy facilities2014

    • Author(s)
      T. Akagi, T. Aso, G. Iwai, A. Kimura, S. Kameoka, S.B. Lee, Y. Maeda, N. Matsufuji, T. Nishio, C. Omachi, S. Park, T. Sasaki, T. Toshito, W. Takase, T. Yamashita and Y. Watase
    • Journal Title

      Progress in Nuclear Science and Technology

      Volume: (accepted for publication)

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Geant4-based particle therapy simulation framework for verification of dose distributions in proton therapy facilities2014

    • Author(s)
      Takashi Akagi,Tsukasa Aso, Go Iwai, Akinori Kimura, Satoru Kameoka, Se Beyong Lee, Yoshikazu Maeda, Naruhito Matsufuji, Teiji Nishio, Chihiro Omachi, Seyjoon Park, Takashi Sasaki, Toshiyuki Toshito, Wataru Takase, Tomohiro Yamashita and Yoshiyuki Watase
    • Journal Title

      Progress in Nuclear Science and Technology

      Volume: 4 Pages: 1-5

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Extension of the Particle Therapy Simulation Framework to Hospital Information Systems and Multi-grid Environments2012

    • Author(s)
      T. Aso, Y. Maeda, G. Iwai, W. Takase, T. Sasaki, Y. Watase, T. Yamashita, T. Akagi and Y. Nakano
    • Journal Title

      IEEE International Conference on Computing and Engineering, IEEE Computer Society

      Pages: 229-234

    • DOI

      10.1109/iccse.2012.39

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effect of inhomogeneity in patient’s body on the accuracy of pencil beam algorithm in comparison to Monte Carlo2012

    • Author(s)
      T.Yamashita, T.Akagi, T.Aso, A.Kimura and T.Sasaki
    • Journal Title

      Physics in Medicine and Biology

      Volume: 57 Issue: 22 Pages: 7673-7688

    • DOI

      10.1088/0031-9155/57/22/7673

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] The PTSim and TOPAS Projects2011

    • Author(s)
      T. Akagi, T. Aso, B. Faddegon, A. Kimura, N. Matsufuji, T. Nishio, C. Omachi, H. Paganetti, J. Perl, T. Sasaki, D. Sawkey, J. Shumann, J. Shin.T. Toshito, T. Yamashita and H. Yoshida
    • Journal Title

      Bringing Geant4 to the Particle Therapy Clinic, Progress in NUCLEAR SCIENCE and TECHNOLOGY

      Volume: Vol. 2 Pages: 912-917

    • URL

      http://www.aesj.or.jp/publication/pnst002/data/912-917.pdf

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] The PTSim and TOPAS Projects, Bringing Geant4 to the Particle Therapy Clinic2011

    • Author(s)
      T.AKAGI, T.ASO, B.FADDEGON, A.KIMURA, N.MATSUFUJI, T. NISHIO, C. OMACHI, H. PAGANETTI, J. PERL, T. SASAKI, D. SAWKEY, J. SCHUMANN, J. SHIN, T.TOSHITO, T. YAMASHITA and H.YOSHIDA
    • Journal Title

      Progress in Nuclear Science and Technology

      Volume: Vol. 2 Pages: 912-917

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] Performance evaluation of Geant4 Based Particle Therapy System Simulation Framework2014

    • Author(s)
      T. Aso, W. Takase, G. Iwai, T. Sasaki, Y. Watase, Y. Maeda, T. Yamashita, T. Akagi, H. Shuuichi, T. Nishio, S.Y. Cai, T.C. Chao, E. Yen, T.H. Wu, Y.T. Lin
    • Organizer
      International Symposium on Grids & Clouds 2014
    • Place of Presentation
      Academia Sinica, Taipei, Taiwan
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
  • [Presentation] Recent Updates and Plan in Geant4 Based Particle Therapy System Simulation Framework2013

    • Author(s)
      T. Aso, T. Akagi, G. Iwai, A. Kimura, Y. Maeda, N. Mastufuji, T. Nishio, C. Omachi, T. Sasaki, W. Takase, T. Toshito, T. Yamashita, Y. Watase
    • Organizer
      IEEE Nuclear Science Symposium and Medical Imaging Conference, Conference Record HT3-8
    • Place of Presentation
      COEX, South Korea
    • Related Report
      2013 Final Research Report
  • [Presentation] Command-Based Interface of Importance Biasing Technique Using Geant4 for Shielding Applications2013

    • Author(s)
      S. Oyama, T. Aso, M. Shimaoka, K. Amako, H. Yoshida, T. Sasaki
    • Organizer
      IEEE Nuclear Science Symposium and Medical Imaging Conference, Conference Record NP02-130
    • Place of Presentation
      COEX, South Korea
    • Related Report
      2013 Final Research Report
  • [Presentation] Common platform of Monte Carlo dose calculation on universal grid interface with Geant4 based particle therapy simulation framework2013

    • Author(s)
      G. Iwai, W. Takase, T. Aso, Y. Watase, T. Sasaki, T. Akagi, T. Yamashita, Y. Maeda, T. Nishio
    • Organizer
      International conference on the use of computers in radiation therapy (ICCR2013)
    • Place of Presentation
      Melbourne Convention and Exhibition Centre, Australia
    • Related Report
      2013 Final Research Report
  • [Presentation] Geant4 based particle therapy system simulation framework with universal grid interface2013

    • Author(s)
      T. Aso, G. Iwai, T. Wataru, T. Sasaki, Y. Watase, Y. Maeda, T. Yamashita, T. Akagi, T. Nishio
    • Organizer
      International Symposium on Grid and Clouds 2013 (ISGC2013)
    • Place of Presentation
      Academia Sinica, Taipei
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] Recent Updates and Plan in Geant4 Based Particle Therapy System Simulation Framework2013

    • Author(s)
      T.Aso, T.Akagi, G.Iwai, A.Kimura, Y.Maeda, N.Mastufuji, T.Nishi, C.Omachi, T.Sasaki, W.Takase, T.Toshito, T.Yamashita, Y.Watase
    • Organizer
      IEEE Nuclear Science Symposium and Medical Imaging Conference
    • Place of Presentation
      COEX, Seoul, South Korea
    • Related Report
      2013 Annual Research Report
  • [Presentation] Command-Based Interface of Importance Biasing Technique Using Geant4 for Shielding Applications2013

    • Author(s)
      S.Oyama, T.Aso, M.Shimaoka, K.Amako, H.Yoshida, T.Sasaki
    • Organizer
      IEEE Nuclear Science Symposium and Medical Imaging Conference
    • Place of Presentation
      COEX, Seoul, South Korea
    • Related Report
      2013 Annual Research Report
  • [Presentation] Common platform of Monte Carlo dose calculation on universal grid interface with Geant4 based particle therapy simulation framework2013

    • Author(s)
      G.Iwai, W.Takase, T.Aso, Y.Watase, T.Sasaki, T.Akagi, T.Yamashita, Y.Maeda, T.Nishio
    • Organizer
      International conference on the use of computers in radiation therapy (ICCR2013)
    • Place of Presentation
      Melnbourne Convention and Exhibition Centre, Australia
    • Related Report
      2013 Annual Research Report
  • [Presentation] Status of Quality Assurance using Particle Therapy Simulation Framework in Particle Therapy Facility in Japan2012

    • Author(s)
      T. Akagi, T. Yamashita, T. Aso, A. Kimura, S. Kameoka, Y. Maeda, N. Matsufuji, T. Nishio, C. Omachi, T. Sasaki, T. Toshito
    • Organizer
      Particle Therapy Workshop in IEEE NSS/MIC Conference
    • Place of Presentation
      Anaheim USA
    • Year and Date
      2012-10-28
    • Related Report
      2013 Final Research Report
  • [Presentation] A GEANT4 BASED PARTICLE THERAPY SIMULATION FRAMEWORK FOR VERIFICATION OF DOSE DISTRIBUTIONS IN PROTON THERAPY FACILITY2012

    • Author(s)
      T. Akagi, T. Aso, G. Iwai, A. Kimura, S. Kameoka, S.B. Lee, Y. Maeda, N. Matsufuji, T. Nishio, C. Omachi, S. Park, T. Sasaki, T. Toshito, W. Takase, T. Yamashita and Y. Watase
    • Organizer
      12th International Conference on Radiation Shielding, Computational Medical Physics Working Group
    • Place of Presentation
      Nara Prefectural New Public Hall, Nara
    • Year and Date
      2012-09-02
    • Related Report
      2013 Final Research Report
  • [Presentation] Extension of the Particle Therapy Simulation Framework to Hospital Information Systems and Multi-grid Environments2012

    • Author(s)
      T. Aso, Y. Maeda, G. Iwai, W. Takase, T. Sasaki, Y. Watase, T. Yamashita, T. Akagi and Y. Nakano
    • Organizer
      IEEE International Conference on Computing and Engineering, IEEE Computer Society
    • Place of Presentation
      Paphos Cyprus
    • Related Report
      2013 Final Research Report
  • [Presentation] A Study on Multiplex Proton Imaging Using GEANT42012

    • Author(s)
      T. Aso, K. Kawashima, T. Nishio, S.B. Lee and T. Sasaki
    • Organizer
      IEEE Nuclear Science Symposium and Medical Imaging Conference, Conference Record
    • Place of Presentation
      Anaheim USA
    • Related Report
      2013 Final Research Report
  • [Presentation] Application of Particle Therapy Simulation on GRID Environments2012

    • Author(s)
      T. Aso, R. Noto, W. Takase, Y. Watase, G. Iwai and T. Sasaki
    • Organizer
      International Symposium on Grids & Clouds 2012
    • Place of Presentation
      Taipei(p.222-223)
    • Related Report
      2013 Final Research Report
  • [Presentation] Extension of the Particle Therapy Simulation Framework to Hospital Information Systems and Multi-grid Environments2012

    • Author(s)
      Tsukasa Aso, Yoshikazu Maeda, Go Iwai, Wataru Takase, Takashi Sasaki, Yoshiyuki Watase, Tomohiro Yamashita, Takashi Akagi and Yuki Nakano
    • Organizer
      IEEE International Conference on Computing and Engineering
    • Place of Presentation
      Paphos, Cyprus
    • Related Report
      2012 Research-status Report
  • [Presentation] A Study on Multiplex Proton Imaging Using GEANT42012

    • Author(s)
      Tsukasa Aso, Kazuki Kawashima, Teiji Nishio, Se Byeong Lee and Takashi Sasaki
    • Organizer
      IEEE Nuclear Science Sympposium and Medical Imaging Conference
    • Place of Presentation
      Anaheim, USA
    • Related Report
      2012 Research-status Report
  • [Presentation] Status of Quality Assurance using Particle Therapy Simulation Framework in Particle Therapy Facility in Japan2012

    • Author(s)
      T. Akagi, T. Yamashita, T.Aso, A.Kimura, S.Kameoka, Y. Maeda, N. Matsufuji, T. Nishio, C.Omachi, T.Sasaki, T.Toshito
    • Organizer
      Hadron Therapy Workshop in IEEE Nuclear Science Symposium and Medical Imaging Conference
    • Place of Presentation
      Anaheim, USA
    • Related Report
      2012 Research-status Report
  • [Presentation] A GEANT4 BASED PARTICLE THERAPY SIMULATION FRAMEWORK FOR VERIFICATION OF DOSE DISTRIBUTIONS IN PROTON THERAPY FACILITY2012

    • Author(s)
      T. Akagi, T.Aso, G. Iwai, A. Kimura, S.Kameoka, S.B.Lee, Y. Maeda, N. Matsufuji, T. Nishio, C.Omachi, S.J.Park, T.Sasaki, T.Toshito, W.Takase, T. Yamashita, Y. Watase, and H. Yoshida
    • Organizer
      12th International Conference on Radiation Shielding, Computational Medical Physics Working Group
    • Place of Presentation
      Nara, JAPAN
    • Related Report
      2012 Research-status Report
  • [Presentation] シミュレーションによる荷電粒子の特性を利用した陽子線画像取得方法の検討2012

    • Author(s)
      川嶋和希,阿蘇司,佐々木節,西尾禎治
    • Organizer
      2012 日本物理学会北陸支部 定例学術講演会
    • Place of Presentation
      金沢大学
    • Related Report
      2012 Research-status Report
  • [Presentation] 放射線治療シミュレーションのユーザインターフェース開発と線量分布の検証2012

    • Author(s)
      中野雄貴,阿蘇司
    • Organizer
      2012 日本物理学会北陸支部 定例学術講演会
    • Place of Presentation
      金沢大学
    • Related Report
      2012 Research-status Report
  • [Presentation] Application of Particle Therapy Simulation on GRID Environments2012

    • Author(s)
      T.Aso, R.Noto, W.Takase, Y.Watase, G.Iwai and T.Sasaki
    • Organizer
      International Symposium on Grids & Clouds 2012
    • Place of Presentation
      Taipei Taiwan
    • Related Report
      2011 Research-status Report
  • [Presentation] RENKEI-NAREGI環境を使った粒子線医療シミュレーション2012

    • Author(s)
      阿蘇司, 高瀬亘,渡瀬芳之,岩井剛,佐々木節
    • Organizer
      e-サイエンス公開シンポジウム REsources liNKage for E-scIence (RENKEI)
    • Place of Presentation
      国立情報学研究所 (東京都)
    • Related Report
      2011 Research-status Report
  • [Presentation] Extensions of DICOM Data interface in Particle Therapy Simulation Framework2011

    • Author(s)
      T. Aso, A. Kimura, T. Sasaki
    • Organizer
      6th Japan-Korea Joint Meeting on Medical Physics/11th Asia-Oceania Congress of Medical Physics
    • Place of Presentation
      Kyusyu Univ(P-1)
    • Related Report
      2013 Final Research Report
  • [Presentation] Particle Therapy Simulation Framework on GRID Environments2011

    • Author(s)
      T. Aso, R. Noto, G. Iwai, T. Sasaki
    • Organizer
      12th IEEE/ACM International Conference on Grid Computing
    • Place of Presentation
      (France) Lyon Conference Center
    • Related Report
      2013 Final Research Report
  • [Presentation] A GEANT4 Based Particle Therapy Simulation Framework2011

    • Author(s)
      T. Aso, A. Kumura, T. Yamashita, T. Akagi, S. Kameoka, T. Nishio, K. Murakami, C. Omachi, T. Sasaki, K. Amako, H. Yoshida, H. Kurashige
    • Organizer
      Particle Therapy Co-Operative Group (PTCOG 50)
    • Place of Presentation
      Philadelphia, USA
    • Related Report
      2013 Final Research Report
  • [Presentation] A GEANT4 Based Particle Therapy Simulation Framework2011

    • Author(s)
      T.Aso, A.Kumura, T.Yamashita, T.Akagi, S.Kameoka, T.Nishio, K.Murakami, C.Omachi, T.Sasaki, K.Amako, H.Yoshida, H.Kurashige
    • Organizer
      Particle Therapy Co-Operative Group (PTCOG 50)
    • Place of Presentation
      Philadelphia USA
    • Related Report
      2011 Research-status Report
  • [Presentation] Extensions of DICOM Data Interface in Particle Therapy Simulation Framework2011

    • Author(s)
      T.Aso, A.Kimura and T.Sasaki
    • Organizer
      6th Japan-Korea Medical Physics (JKMP), 11th Asia-Oceania Congress of Medical Physics
    • Place of Presentation
      Fukuoka JAPAN
    • Related Report
      2011 Research-status Report
  • [Presentation] Particle Therapy Simulation Framework on GRID environments2011

    • Author(s)
      T.Aso, R.Noto, G.Iwai, W.Takase, T.Sasaki
    • Organizer
      2011 12th IEEE/ACM International Conference Grid Computing (GRID2011)
    • Place of Presentation
      Lyon France
    • Related Report
      2011 Research-status Report
  • [Presentation] シミュレーションによる荷電粒子の特性を利用した陽子線画像取得方法の検討2011

    • Author(s)
      川嶋和希, 阿蘇司, 佐々木節, 西尾禎治
    • Organizer
      日本物理学会北陸支部 定例学術講演会
    • Place of Presentation
      福井大学(福井県)
    • Related Report
      2011 Research-status Report
  • [Presentation] X 線治療での 2 次粒子情報を利用した線量取得方法のシミュレーションによる検討2011

    • Author(s)
      中野雄貴, 阿蘇司, 西尾禎治, 佐々木節
    • Organizer
      日本物理学会北陸支部 定例学術講演会
    • Place of Presentation
      福井大学(福井県)
    • Related Report
      2011 Research-status Report
  • [Presentation] 臓器物質の割当を考慮した陽子線医療シミュレーションの開発2011

    • Author(s)
      坂上和至, 阿蘇司, 谷内飛鳥, 安田真奈美
    • Organizer
      日本物理学会北陸支部 定例学術講演会
    • Place of Presentation
      福井大学(福井県)
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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