Control of magnetic anisotropy in the gold-magnetic heterostructure nanoparticles using the ligand molecules and application to the magnetic hyperthermia therapy

• Project/Area Number: 23540386
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Condensed matter physics II
• Research Institution: Akita University
• Principal Investigator: YAMAMOTO Yoshiyuki 秋田大学, 工学(系)研究科(研究院), 准教授 (70322120)
• Project Period (FY): 2011-04-28 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: 磁性 / ナノ材料 / 物性実験 / 表面・界面物性 / 金属物性

Outline of Final Research Achievements

In this study, we aim to observe the change of magnetic properties in the gold-magnetic heterostructure nanoparticles induced by the coordination of organic molecule on the surface gold atoms and develop the nanoparticles as a heating mediator for the magnetic hyperthermia therapy. Gold-iron oxide nanoparticles with gold-magnetic hetero interface were synthesized and capping oleylamine molecule was exchanged by dimercaptosuccinic acid while magnetic core nanoparticle was unchanged. Magnetic heating experiments showed that the increase of specific absorption rate for the nanoparticles capped with dimercaptosuccinic acid compared to the ones with oleylamine. These results imply that magnetic properties of heterostructure nanoparticles are influenced by the capping molecule and the importance of roughness at the interface is revealed.

Research Products

• [Journal Article] Size dependence study on magnetic heating properties of superparamagnetic iron oxide nanoparticles suspension (2014)
  • Author(s): Y. Yamamoto, K. Horiuchi, M. Takeuchi, N. Tanaka, R. Aihara, N. Takeuchi, and S. Fujita
  • Journal Title: Journal of Applied Physics Volume: 116 Issue: 12
  • DOI: 10.1063/1.4896369
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Si Interlayer Thickness Dependence of Hysteresis Loop in Co/Si/Co/GaAs(001) (2012)
  • Author(s): J. Islam, Y. Yamamoto, E. Shikoh, A. Fujiwara, and H. Hori
  • Journal Title: J. Sci. Res. Volume: 4 Issue: 3 Pages: 561-567
  • DOI: 10.3329/jsr.v4i3.10852
  • Peer Reviewed
• [Journal Article] Measurement of a Pauli and Orbital Paramagnetic State in Bulk Gold Using X-Ray Magnetic Circular Dichroism Spectroscopy (2012)
  • Author(s): M.Suzuki, N.Kawamura, H.Miyagawa, J.S.Garitaonandia, Y.Yamamoto, and H.Hori
  • Journal Title: Phys. Rev. Lett. Volume: 108 Issue: 4 Pages: 47201-47201
  • DOI: 10.1103/physrevlett.108.047201
  • Peer Reviewed
• [Presentation] 金－酸化鉄ヘテロ構造ナノ粒子の磁性と磁気温熱特性 (2013)
  • Author(s): 山本良之，日向宏高，常前孝彰，入枝孝憲，長澤洋介
  • Organizer: 日本物理学会第68回年次大会
  • Place of Presentation: 広島大学 東広島キャンパス
• [Presentation] DMFに保護された金ナノクラスターの磁気特性 (2012)
  • Author(s): 吉原 義浩，松尾 晶，川崎 英也，山本 良之，金道 浩一，齊藤 正，稲田 貢
  • Organizer: 第73回応用物理学会学術講演会
  • Place of Presentation: 愛媛大学 城北地区
• [Presentation] 磁気光学効果によるフェライトナノ粒子の交流帯磁率測定 (2012)
  • Author(s): 山本良之，堀内公平，竹内昌宏，田中直樹
  • Organizer: 日本物理学会第67回年次大会
  • Place of Presentation: 関西学院大学 西宮上ヶ原キャンパス
• [Presentation] マグネタイト－金コアシェル型ナノ粒子の磁性と磁気温熱特性 (2011)
  • Author(s): 山本良之，堀内公平，竹内昌宏，田中直樹
  • Organizer: 日本物理学会2011年秋季大会
  • Place of Presentation: 富山大学 五福キャンパス