Control of magnetic anisotropy in the gold-magnetic heterostructure nanoparticles using the ligand molecules and application to the magnetic hyperthermia therapy
| Project/Area Number |
23540386
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Condensed matter physics II
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| Research Institution | Akita University |
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Principal Investigator |
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| Project Period (FY) |
2011-04-28 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 磁性 / ナノ材料 / 物性実験 / 表面・界面物性 / 金属物性 |
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| Outline of Final Research Achievements |
In this study, we aim to observe the change of magnetic properties in the gold-magnetic heterostructure nanoparticles induced by the coordination of organic molecule on the surface gold atoms and develop the nanoparticles as a heating mediator for the magnetic hyperthermia therapy. Gold-iron oxide nanoparticles with gold-magnetic hetero interface were synthesized and capping oleylamine molecule was exchanged by dimercaptosuccinic acid while magnetic core nanoparticle was unchanged. Magnetic heating experiments showed that the increase of specific absorption rate for the nanoparticles capped with dimercaptosuccinic acid compared to the ones with oleylamine. These results imply that magnetic properties of heterostructure nanoparticles are influenced by the capping molecule and the importance of roughness at the interface is revealed.
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Report
(5 results)
Research Products
(7 results)
