Development of Matal Complex Sensor Possessing a Neurotransmitter-Responce on Near-Infrared Spectroscopy
Project/Area Number |
23550104
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Analytical chemistry
|
Research Institution | Sophia University |
Principal Investigator |
|
Project Period (FY) |
2011 – 2013
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 糖認識 / 化学センサー / 近赤外吸収 / ルテニウム錯体 / 吸収スペクトル / シクロデキストリン / 超分子複合体 / ドーパミン / 分子認識 / カテコールアミン / フェニルボロン酸 / β-ジケトナト錯体 / 神経伝達物質 / 錯体化学 / 電気化学 / 近赤外光 / ルテニウム |
Research Abstract |
The purpose of this study is to develop a neurotransmitter response on near-infrared spectroscopy using (.beta.-diketonato) ruthenium complexes. To realize this objective, a naphthylboronic acid-coordinated (.beta.-diketonato)ruthenium complex has been designed and synthesized. This metal complex was evaluated with electrochemistry and electronic spectra. The results revealed that this complex exhibited a near-infrared absorption band and a sugar recognition function in 80% water – 20% acetonitrile solution. Moreover, the dopamine recognition function of the supramolecular chromogenic probe/cyclodextrin complex was evaluated from their UV-Vis or fluorescence spectra in aqueous solution.
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Report
(4 results)
Research Products
(83 results)