Asymmetric synthesis and chiral separation in chiral MOF nanocavity
| Project/Area Number |
23550129
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Kansai University |
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Principal Investigator |
TANAKA Koichi 関西大学, 化学生命工学部, 教授 (10116949)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | ＭＯＦ / ナノ細孔 / 不斉合成 / キラル分離 / 配位高分子 / 有機化学 / 触媒 / 不斉反応 / 光学異性体 / 分離 / 結晶構造 / 分子認識 / MOF / 金属有機構造体 / 不均一系触媒 / 多孔性金属‐有機構造体 / 有機配位子 / キラルＭＯＦ / ビナフチルジカルボン酸 / 三次元細孔構造 / 単結晶X線解析 / 固体ＣＤスペクトル |
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| Research Abstract |
Some novel chiral porous MOF crystals with BINOL unit were synthesized and their applications to the heterogeneous catalyst for the asymmetric ring opening reaction of styrene oxide, methanolytic kinetic resolution of epoxides, and asymmetric oxidation of sulfide to sulfoxide were successfully studied. We also developed a new homochiral MOF-silica composite and chiral chromatographic separation of racemic mixtures of various sulfoxides, sec-alcohols and beta-lactams over the homochiral MOF-silica composite as the stationary phase.
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Report
(4 results)
Research Products
(68 results)
