Research on brain injury mechanism by quantitative analysis of the tissue damage
| Project/Area Number |
23560100
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Materials/Mechanics of materials
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| Research Institution | Nihon University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 生体力学 / インパクトバイオメカニクス / 頭部外傷 / 脳特性 / 自動車安全 / バイオメカニクス / 脳損傷 / 安全安心 / 自動車の安全 / 衝撃生体力学 |
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| Research Abstract |
The aim of this study was to examine micro injuries of brain tissue to gain a better understanding of head injury tolerance.In the animal impact tests due to head jury mechanism, we developed new head rotational impact apparatus of porcine. Compression stress relaxation experiments were conducted in vitro, using porcine brain tissue and subsequently analysed using stain methods. The distribution of the damage ratio of the transverse length to the longitudinal length of brain nerve cells in the brain tissue under loading was also examined. This indicated that at a compression strain of 30% or greater the aspect ratio exceeded 2.0. The results of this study show that a compression strain of 30% corresponds to the threshold for the extreme aspect ratio of 2.0; where the transverse length of deformed nerve cell is two times greater than longitudinal length.
Research involving animal tests was approved by the Ethics Committee of Nihon University with the approval number AP11E003.
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Report
(4 results)
Research Products
(55 results)
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[Presentation] 医用画像に基づく動物脳のボクセルモデル構築2011
Author(s)
寺島征哉,西本哲也,渡邉大,Jeffrey Dutschke, Robert Anderson
Organizer
日本機械学会スポーツ・アンド・ヒューマンダイナミクス2011
Place of Presentation
京都大学(A42,No.11-17,223-224)
Year and Date
2011-11-02
Related Report
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