Proposal of design of highly functional 3D structured scaffold for rebuilding bone tissue and process for its structure control

• Project/Area Number: 23560108
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Materials/Mechanics of materials
• Research Institution: Kinki University
• Principal Investigator: KYOGOKU Hideki 近畿大学, 工学部, 教授 (10258056)
• Co-Investigator(Renkei-kenkyūsha): YOSHIKAWA Kenichi 独立行政法人理化学研究所, 素形材工学研究室, 共同研究員 (30525902)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000); Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2011: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
• Keywords: 材料加工・処理 / 生体材料

Research Abstract

The aim of this research is to propose the design of highly functional 3D structured scaffold for rebuilding bone tissue and the process for its structure control to fabricate the new structured scaffold by using titanium and titanium alloys which have superior biocompatibility and strength. The design of highly functional 3D structured scaffold for rebuilding bone tissue was proposed. The titanium scaffold could be fabricated by investigating the fabrication conditions of direct laser melting process. And also, the effect of the third element on the biocompatibility and deformation behavior of the Ti-Nb alloys was investigated. The alloy having the elasticity near human bone could be fabricated by using pulse-current sintering method.

Research Products

• [Journal Article] Fabrication of Ti-Nb alloys by Powder Metallurgy Process and their Shape Memory Characteristics (2013)
  • Author(s): A. Terayama, N. Fuyama, Y. Yamashita, I. Ishizuka, H. Kyogoku
  • Journal Title: Journal of Alloys and Compounds Volume: vol.577S
  • Peer Reviewed
• [Journal Article] Surface Morphology of Selective Laser-Melted Titanium (2013)
  • Author(s): H. Kyogoku, Y. Shimizu, K. Yoshikawa
  • Journal Title: Proceedings of Solid Freeform Fabrication Symposium 2013 Pages: 846-852
  • Peer Reviewed
• [Journal Article] Effect of Cu Addition on Shape Memory Characteristics of Ti-Nb Based Alloy Fabricated by Pulse Current Sintering (2013)
  • Author(s): H. Kyogoku, D. Ohishi, A. Terayama
  • Journal Title: Proceedings of the 2012 Powder Metallurgy World Congress and Exhibition Volume: (CD-ROM)
  • Peer Reviewed
• [Journal Article] Fabrication of Ti-Nb alloys by Powder Metallurgy Process and their Shape Memory Characteristics (2013)
  • Author(s): A. Terayama, N. Fuyama, Y. Yamashita, I. Ishizuka, h. Kyogoku
  • Journal Title: Journal of Alloys and Compounds Volume: 577S Pages: S408-S412
  • DOI: 10.1016/j.jallcom.2011.12.166
  • Peer Reviewed
• [Journal Article] Fabrication of Ti-Sn-Cr Shape Memory Alloy by PM Process (2012)
  • Author(s): S. Ashida, H. Kyogoku, H. Hosoda
  • Journal Title: Materials Science Forum Volume: Vols.706-709 Pages: 1943-1947
  • Peer Reviewed
• [Journal Article] Effect of Cu Addition on Shape Memory Characteristics of Ti-Nb Based Alloy Fabricated by Pulse Current Sintering (2012)
  • Author(s): H. Kyogoku, D. Ohishi, A. Terayama
  • Journal Title: Proceedings of the 2012 Powder Metallurgy World Congress and Exhibition (CD-ROM) Volume: なし
  • Peer Reviewed
• [Presentation] Surface Morphology of Selective Laser-Melted Titanium (2013)
  • Author(s): H. Kyogoku, Y. Shimizu, K. Yoshikawa
  • Organizer: Solid Freeform Fabrication Symposium 2013
  • Place of Presentation: The University of Texas at Austin, (Austin TX)
  • Year and Date: 2013-08-12
• [Presentation] 純チタンの各種成形法による表面微細形状がヒト由来培養細胞に及ぼす影響 (2013)
  • Author(s): 石幡浩志,岩間張良,小林洋子,佐々木啓一,島内英俊、吉川研一、京極秀樹
  • Organizer: 粉体粉末冶金協会平成25年度春季大会
  • Place of Presentation: 早稲田大学(東京)
  • Year and Date: 2013-05-29
• [Presentation] Shape Memory Properties of PM Processed Ti-Sn-Cr Alloy (2013)
  • Author(s): S. Ashida, H. Kyogoku, H. Hosoda
  • Organizer: The International Conference on Shape Memory and Superelastic Technologies (SMST2013)
  • Place of Presentation: OREA Hotel Pyaramida(Prague, Czech Republic)
• [Presentation] MA粉末を利用したTi-Sn-Cr合金の形状記憶特性 (2012)
  • Author(s): 芦田真一,京極秀樹
  • Organizer: 日本機械学会第20回機械材料・材料加工部門技術講演会
  • Place of Presentation: 大阪工業大学(大阪)
  • Year and Date: 2012-12-01
• [Presentation] Effect of Cu Addition on Shape Memory Characteristics of Ti-Nb Based Alloy Fabricated by Pulse Current Sintering (2012)
  • Author(s): H. Kyogoku, D. Ohishi, A. Terayama
  • Organizer: Powder Metallurgy World Congress and Exhibition
  • Place of Presentation: Pacifico Yokohama (Yokohama)
  • Year and Date: 2012-10-17
• [Presentation] 粉末冶金法により作製したTi-Nb-Cu合金の形状記憶特性 (2012)
  • Author(s): 京極秀樹,寺山朗
  • Organizer: 日本機械学会2012年度年次大会
  • Place of Presentation: 金沢大学(金沢)
  • Year and Date: 2012-09-11
• [Presentation] Surface Morphology of Selective Laser-Melted Titanium
  • Author(s): H. Kyogoku, Y. Shimizu, K. Yoshikawa
  • Organizer: Solid Freeform Fabrication Symposium 2013
  • Place of Presentation: Austin TX, USA
• [Presentation] 最近のファイバーレーザ積層造形技術の動向
  • Author(s): 京極秀樹
  • Organizer: 粉体粉末冶金協会平成25年度秋季大会
  • Place of Presentation: 名古屋国際会議場（名古屋）
  • Invited
• [Presentation] ３Dプリンターの開発動向
  • Author(s): 京極秀樹
  • Organizer: レーザー学会第34回年次大会「創立40周年記念講演」
  • Place of Presentation: 北九州国際会議場（北九州）
  • Invited
• [Presentation] 粉末冶金法により作製したTi-Nb-Cu合金の形状記憶特性
  • Author(s): 京極秀樹、寺山朗
  • Organizer: 日本機械学会2012年度年次大会
  • Place of Presentation: 金沢大学（金沢）
• [Presentation] Effect of Cu Addition on Shape Memory Characteristics of Ti-Nb Based Alloy Fabricated by Pulse Current Sintering
  • Author(s): H. Kyogoku, D. Ohishi, A. Terayama
  • Organizer: 2012 Powder Metallurgy World Congress and Exhibition
  • Place of Presentation: Pacifico Yokohama(Yokohama)
• [Presentation] MA粉末を利用したTi-Sn-Cr合金の形状記憶特性
  • Author(s): 芦田真一、京極秀樹
  • Organizer: 日本機械学会第20回機械材料・材料加工部門技術講演会
  • Place of Presentation: 大阪工業大学（大阪）
• [Presentation] レーザ積層造形技術の動向と実際
  • Author(s): 京極秀樹
  • Organizer: 第78回レーザ加工学会
  • Place of Presentation: アクトシティ浜松コングレスセンター（浜松）
  • Invited
• [Presentation] チタン粉末のレーザ積層造形
  • Author(s): 京極秀樹、志水勇史、吉川研一
  • Organizer: 日本機械学会2011年度年次大会
  • Place of Presentation: 東京工業大学（東京都）
• [Presentation] 粉末冶金法によるTi-Nb-Cu形状記憶合金の作製とその特性
  • Author(s): 大石大二郎、京極秀樹、寺山朗
  • Organizer: 日本機械学会2011年度年次大会
  • Place of Presentation: 東京工業大学（東京都）
• [Remarks]
  • URL: http://WWW.hiro.kindai.ac.jp
• [Remarks] 近畿大学次世代基盤技術研究所報告