The study of the generating and affecting of the high intensity burst pulse electromagnetic wave for the cancer treatment method using the ultra-short pulsed high electric field
| Project/Area Number |
23560312
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Power engineering/Power conversion/Electric machinery
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| Research Institution | Yamagata University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | がん治療 / アポトーシス / 超短パルス高電界 / パルス電磁波 / SOSダイオード / 高周波バーストパルス / 共振伝送線路 / 磁気スイッチ / 出芽酵母 / HeLa細胞 / 非線形伝送線路 / 磁気共鳴 / 分散 / がん細胞 |
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| Research Abstract |
This work focuses on the design of a compact high power pulsed electromagnetic wave generator using a nanosecond pulsed power generator to apply a high-intensity electric field for a cancer treatment. In previous study, since the output voltage waveform of the pulsed power generator was damping oscillation, the duration of the burst pulse was under 100 ns. So the generator uses a magnetic switch instead of the gap switch and uses a SOS diode with current cutoff time of nanoseconds. The cluster pulse has 6 burst pulses that continue for 3000 ns. And the effect of frequency of burst pulse high electric field on HeLa cells has been clarified.
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Report
(4 results)
Research Products
(31 results)
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[Presentation] The dependence of protein expression level in HeLa cells on the frequency of high frequency burst pulse high electric field2012
Author(s)
Yasushi Minamitani, Yoshie Kuramochi, Takashi Toyooka, Kazuki Shinagawa, Kazunori Mitsutake, Misako Yano, Masaya, Morotomi, Sunao Katsuki, Hidenori Akiyama
Organizer
2012 International Bioelectrics Symposium
Place of Presentation
熊本市,KKRホテル熊本
Year and Date
2012-09-07
Related Report
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