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Development of voxel based vibro-Doppler imaging method for in-vivo measurement

Research Project

Project/Area Number 23560499
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Measurement engineering
Research InstitutionGunma University

Principal Investigator

MIWA Takashi  群馬大学, 理工学研究院, 准教授 (30313414)

Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords計測システム / 超音波 / 超音波計測 / ドップラ計測 / 組織弾性 / イメージング / 医用超音波
Research Abstract

Quantitative measurement of shear wave velocity for living tissue might give valuable information in medical diagnoses. In this report, a novel imaging method based on low frequency vibration wave (LFVW) is proposed.
In order to improve the accuracy, we introduce 3-D Doppler signal acquisition and 3-D LFVW-wave number vector filtering. By this algorithm, propagation characteristics of each LFVW can be evaluated in tissue where standing wave, reflected wave and refracted wave exist at the same time. In order to estimate small displacement of the tissue, we introduce arc-tangent based tissue displacement estimation at the vibration frequency.
Experiments in two-layered phantom show that LFVW velocity can be estimated with standard deviation of less than 5% for the window aperture of 1 cm. It is demonstrated that 500 Hz shear wave is successfully measured for muscle of upper-arm in-vivo.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (39 results)

All 2013 2012 2011

All Journal Article (17 results) (of which Peer Reviewed: 16 results) Presentation (20 results) Patent(Industrial Property Rights) (2 results) (of which Overseas: 1 results)

  • [Journal Article] Improvement of horizontal resolution by Doppler image under forced vibration2013

    • Author(s)
      T. Miwa
    • Journal Title

      Key Engineering Materials

      Volume: 596 Pages: 152-157

    • DOI

      10.4028/www.scientific.net/kem.596.152

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of skin dermis microcirculation in flow-mediated dilation using optical sensor with pressurization mechanism2013

    • Author(s)
      Y. Yamakoshi, K. Kotani, N. Taniguchi and T. Miwa
    • Journal Title

      Med. Biol. Eng. Comput

      Volume: 51 Issue: 5 Pages: 497-505

    • DOI

      10.1007/s11517-012-1017-2

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Velocity filter based tissue elasticity imaging for low frequency vibration wave method2013

    • Author(s)
      T. Miwa, Y. Yoshihara, and Y. Yamakoshi
    • Journal Title

      Key Engineering Materials

      Volume: 534 Pages: 267-272

    • DOI

      10.4028/www.scientific.net/kem.534.267

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Anisotropy evaluation of in-vivo tissue elasticity measure- ment by using wavenumber filtering2013

    • Author(s)
      T. Miwa and Y. Yamakoshi
    • Journal Title

      Key Engineering Materials

      Volume: 534 Pages: 262-266

    • DOI

      10.4028/www.scientific.net/kem.534.262

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Observation of Microhollows produced by Bubble Cloud Cavitation2012

    • Author(s)
      Y. Yamakoshi and T. Miwa
    • Journal Title

      Jpn. J. Appl. Phys.

      Volume: 51 Issue: 7S Pages: 07GF28-07GF28

    • DOI

      10.1143/jjap.51.07gf28

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Tissue visco-elasticity measurement system by simultaneous multiple-frequency excitation2012

    • Author(s)
      T. Miwa, Y. Yoshihara, K. Kanzawa, R. K. Parajuli, and Y. Yamakoshi
    • Journal Title

      Jpn. J. Appl. Phys.

      Volume: 51 Issue: 7S Pages: 07GF13-07GF13

    • DOI

      10.1143/jjap.51.07gf13

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Simulator for application of shear wave velocity measurement system to arbitrary tissue elasticity distribution2012

    • Author(s)
      T. Miwa and Y. Yamakoshi
    • Journal Title

      Key Engineering Materials

      Volume: 497 Pages: 161-168

    • DOI

      10.4028/www.scientific.net/kem.497.161

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Phantom experiments on shear wave velocity measurement by virtual sensing array spectrum estimation2012

    • Author(s)
      T. Miwa, K. Kanzawa, R. Tomizawa, and Y. Yamakoshi
    • Journal Title

      Key Engineering Materials

      Volume: 497 Pages: 153-160

    • DOI

      10.4028/www.scientific.net/kem.497.153

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 連続波加振による組織弾性映像系の開発2012

    • Author(s)
      三輪空司, 山越芳樹
    • Journal Title

      超音波TECHNO

      Volume: 24 Pages: 93-97

    • Related Report
      2012 Research-status Report
  • [Journal Article] Phantom Experiments on Shear Wave Velocity Measurement by Virtual Sensing Array Spectrum Estimation2012

    • Author(s)
      T. Miwa, K. Kanzawa, R. Tomizawa, and Y. Yamakoshi
    • Journal Title

      Key Engineering Materials

      Volume: Vol. 497 Pages: 153-160

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Simulator for Application of Shear Wave Velocity Measurement System to Arbitrary Tissue Elasticity Distribution2012

    • Author(s)
      T. Miwa and Y. Yamakoshi
    • Journal Title

      Key Engineering Materials

      Volume: Vol. 497 Pages: 161-168

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Shear wave velocity estimation by virtual sensing array spectrum analysis2011

    • Author(s)
      T. Miwa, R. K. Parajuli, R. Tomizawa, and Y. Yamakoshi
    • Journal Title

      Jpn. J. Appl. Phys

      Volume: 50, 07HF07-1-9 Issue: 7S Pages: 07HF07-07HF07

    • DOI

      10.1143/jjap.50.07hf07

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of Ultrasonic Wave Irradiation Sequence in Micro Hollow Production Produced by Bubble Cavitation2011

    • Author(s)
      Y.Yamakoshi, T.Miwa
    • Journal Title

      Jpn.J.Appl.Phys.

      Volume: 50 Issue: 7S Pages: 07HF01-07HF01

    • DOI

      10.1143/jjap.50.07hf01

    • NAID

      210000070950

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Tx and Rx Modulation MIMO Radar System with Orthogonal Codes2011

    • Author(s)
      T. Miwa, Y. Nakano and Y. Yamakoshi
    • Journal Title

      IEICE Transactions on Communications

      Volume: E94-B Issue: 2 Pages: 546-553

    • DOI

      10.1587/transcom.E94.B.546

    • NAID

      10028230618

    • ISSN
      0916-8516, 1745-1345
    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Interdigital ring coupler sensor for parameter estimation of moving objects2011

    • Author(s)
      T. Miwa and Y. Yamakoshi
    • Journal Title

      Key Engineering Materials

      Volume: 459 Pages: 190-193

    • DOI

      10.4028/www.scientific.net/kem.459.190

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dynamics simulation of microbubbles in ultrasonic wave field considering the secondary Bjerknes force2011

    • Author(s)
      T.Miwa, Y.Yamakoshi
    • Journal Title

      Key Engineering Materials

      Volume: 459 Pages: 271-276

    • DOI

      10.4028/www.scientific.net/kem.459.271

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Shear Wave Velocity Estimation by Virtual Sensing Array Spectrum Analysis2011

    • Author(s)
      T. Miwa, R. K. Parajuli, R. Tomizawa, and Y. Yamakoshi
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: Vol. 50

    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Presentation] マイクロ波によるRC構造物中の腐食鉄筋探査の一検討2013

    • Author(s)
      三輪空司
    • Organizer
      電子情報通信学会SANE研究会
    • Place of Presentation
      仙台
    • Year and Date
      2013-11-22
    • Related Report
      2013 Final Research Report
  • [Presentation] 掘削時前方探査レーダのためのバケット一体型八木宇田スロットアンテナの設計2013

    • Author(s)
      茂木優人、三輪空司
    • Organizer
      電子情報通信学会SANE研究会
    • Place of Presentation
      仙台
    • Year and Date
      2013-11-22
    • Related Report
      2013 Final Research Report
  • [Presentation] マイクロ波によるRC構造物中の腐食鉄筋探査の一検討2013

    • Author(s)
      三輪空司
    • Organizer
      電子情報通信学会・宇宙・航行エレクトロニクス研究会
    • Place of Presentation
      仙台
    • Related Report
      2013 Annual Research Report
  • [Presentation] 掘削時前方探査レーダのためのバケット一体型八木・宇田スロットアンテナの設計2013

    • Author(s)
      茂木優人、三輪空司
    • Organizer
      電子情報通信学会・宇宙・航行エレクトロニクス研究会
    • Place of Presentation
      仙台
    • Related Report
      2013 Annual Research Report
  • [Presentation] Super-resolution Imaging using forced vibration2012

    • Author(s)
      T. Miwa and A. Kaneko
    • Organizer
      Int. Conf. on Advanced Micro Device Engineering
    • Place of Presentation
      Kiryu
    • Year and Date
      2012-12-07
    • Related Report
      2013 Final Research Report
  • [Presentation] Improvement of cross range resolution in B-mode image by US Doppler measurement with forced vibration2012

    • Author(s)
      T. Miwa and A. Kaneko
    • Organizer
      超音波シンポジウム
    • Place of Presentation
      千葉
    • Year and Date
      2012-11-14
    • Related Report
      2013 Final Research Report
  • [Presentation] Improvement of cross range resolution in B-mode image by US Doppler measurement with forced vibration2012

    • Author(s)
      T. Miwa and A. Kaneko
    • Organizer
      Symposium on Ultrasonic Symposium 2012
    • Place of Presentation
      Chiba
    • Related Report
      2012 Research-status Report
  • [Presentation] Super-resolution imaging using forced vibration2012

    • Author(s)
      T. Miwa and A. Kaneko
    • Organizer
      Int. conf. on Advanced Micro Device Engineering
    • Place of Presentation
      Kiryu
    • Related Report
      2012 Research-status Report
  • [Presentation] Tissue Elasticity imaging based on wave number filtering2011

    • Author(s)
      T. Miwa, Y. Yamakoshi
    • Organizer
      Int. Conf. on Advanced Micro Device Engineering
    • Place of Presentation
      Kiryu
    • Year and Date
      2011-12-08
    • Related Report
      2013 Final Research Report
  • [Presentation] 層構造を有する生体組織のずり弾性波伝搬2011

    • Author(s)
      吉原由貴、神澤高貴、ラジクマルパラジュリ、三輪空司、山越芳樹
    • Organizer
      日本超音波医学会関東甲信越地方大会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-30
    • Related Report
      2013 Final Research Report
  • [Presentation] 生体内ずり弾性波映像化におけるFDTDシミュレーション法の有用性2011

    • Author(s)
      中居大輔、神澤高貴、ラジクマルパラジュリ、三輪空司、山越芳樹
    • Organizer
      日本超音波医学会関東甲信越地方大会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-30
    • Related Report
      2013 Final Research Report
  • [Presentation] Novel tissue elasticity imaging by 3D low frequency vibration wave measurement2011

    • Author(s)
      T. Miwa, R. K. Parajuli, Y. Yamakoshi
    • Organizer
      World Congress of Ultrasound in Medicine and Biology
    • Place of Presentation
      Vienna
    • Year and Date
      2011-08-29
    • Related Report
      2013 Final Research Report
  • [Presentation] マルチスペクトラム同時加振によるずり弾性波映像化2011

    • Author(s)
      吉原由貴、富沢良介、ラジクマルパラジュリ、三輪空司、山越芳樹
    • Organizer
      第84回日本超音波医学会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-27
    • Related Report
      2013 Final Research Report
  • [Presentation] 生体内ずり弾性波映像化のためのマルチスペクトル3次元計測システム2011

    • Author(s)
      神澤高貴、富沢良介、ラジクマルパラジュリ、三輪空司、山越芳樹
    • Organizer
      第84回日本超音波医学会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-27
    • Related Report
      2013 Final Research Report
  • [Presentation] Novel tissue elasticity imaging by 3-D low frequency vibration wave measurement2011

    • Author(s)
      T. Miwa, R.K. Parajuli, Y. Yamakoshi
    • Organizer
      World Congress of Ultrasound in Medicine and Biology
    • Place of Presentation
      ウィーン(オーストリア)
    • Related Report
      2011 Research-status Report
  • [Presentation] Tissue elasticity imaging based on wave number vector filtering2011

    • Author(s)
      T. Miwa, and Y. Yamakoshi
    • Organizer
      3rd International Conference on Advanced Micro Device Engineering
    • Place of Presentation
      桐生市市民文化会館(群馬)
    • Related Report
      2011 Research-status Report
  • [Presentation] マルチスペクトラム同時加振によるずり弾性波映像化2011

    • Author(s)
      吉原由貴, 冨沢良介, パラジュリラジュクマル, 三輪空司, 山越芳樹
    • Organizer
      日本超音波医学会第84回学術集会
    • Place of Presentation
      プリンスホテル高輪(東京)
    • Related Report
      2011 Research-status Report
  • [Presentation] 生体内ずり弾性波映像化のためのマルチスペクトル3次元計測システム2011

    • Author(s)
      神澤高貴, 冨沢良介, パラジュリラジュクマル, 三輪空司, 山越芳樹
    • Organizer
      日本超音波医学会第84回学術集会
    • Place of Presentation
      プリンスホテル高輪(東京)
    • Related Report
      2011 Research-status Report
  • [Presentation] 層構造を有する生体組織のずり弾性波伝搬2011

    • Author(s)
      吉原由貴, 神澤高貴, パラジュリラジュクマル, 三輪空司, 山越芳樹
    • Organizer
      日本超音波医学会関東甲信越地方会23回学術集会
    • Place of Presentation
      ビッグサイトTFTホール(東京)
    • Related Report
      2011 Research-status Report
  • [Presentation] 生体内ずり弾性波映像化におけるFDTDシミュレーション法の有用性2011

    • Author(s)
      中居大輔, 神澤高貴, パラジュリラジュクマル, 三輪空司, 山越芳樹
    • Organizer
      日本超音波医学会関東甲信越地方会23回学術集会
    • Place of Presentation
      ビッグサイトTFTホール(東京)
    • Related Report
      2011 Research-status Report
  • [Patent(Industrial Property Rights)] 映像装置及び映像形成方法2013

    • Inventor(s)
      三輪空司
    • Industrial Property Rights Holder
      三輪空司
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-05-09
    • Related Report
      2013 Final Research Report
    • Overseas
  • [Patent(Industrial Property Rights)] 映像装置及び映像形成方法2013

    • Inventor(s)
      三輪空司
    • Industrial Property Rights Holder
      三輪空司
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-099248
    • Filing Date
      2013-05-09
    • Related Report
      2013 Annual Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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