Regulation of homeostasis by absorption and excretion in the digestive tract
Project/Area Number |
23570006
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Genetics/Genome dynamics
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Research Institution | Okayama University |
Principal Investigator |
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Research Collaborator |
KIFUKU Naoto 岡山大学, 大学院自然科学研究科, 大学院生
|
Project Period (FY) |
2011 – 2013
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | ショウジョウバエ / マルピーギ管 / ストレス応答 / 排泄 / プロトンポンプ / セプテートジャンクション |
Research Abstract |
Malpighian tubules of Drosophila melanogaster have functions homologous to those of mammalian kidney, and maintain homeostasis by excreting waste matter from the body fluid. This study has shown that the homeodomain transcription factor Defective proventriculus (Dve) is essential for functional differentiation of these cells and their stress response to high-salt diet.
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Report
(4 results)
Research Products
(15 results)
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[Journal Article] Pranidhi Sood, Nina Vogt, Rudy Behnia, Daniel Vasiliauskas, Elizabeth McDonald, Baotong Xie, Sebastian Koenig, Reinhard Wolf, Tiffany Cook, Brian Gebelein, Edo Kussell, Hideki Nakagoshi* and Claude Desplan* (* corresponding authors) Interlocked feedforward loops control cell-type-specic Rhodopsin expression in the Drosophila eye2011
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