| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Research Abstract |
The molecular and neuronal mechanisms for the germline-mediated regulation of the chemotactic behaviorAnimals adequately change their behavioral patterns according to their developmental stage. We found that C. elegans larvae show a different preference in odorant from the adult. We also found that the germline loss makes adult animals show the larva-like odorant preference. These results implicate that some signals may be released from germline cells, which proliferate through the larval stages and the adult. By mutant analyses and a genome-wide RNAi screening, the energy state of the animal during larval stages is shown to be important for the germline-mediated regulation of chemotaxis.
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