| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
|---|
| Research Abstract |
Ci-VP is an oxytocin/vasopressin superfamily peptide identified from an ascidian, Ciona intestinalis. We generated a transgenic ascidian that contains Ci-VP promoter region conjugated with a fluorescence protein gene. The Ci-VP promoter-regulated fluorescence protein was detected in the ovary of the young transgenic ascidian. Indeed, Ci-VP mRNA was also detected in the ovary of wild young ascidians, and several small cells in the ovary contain Ci-VP mRNA. Moreover, administration of Ci-VP to the ovary of young ascidians induced expression of several genes promoting cell prolification. These results suggest that Ci-VP serves as not only a neuropeptide but also an ovarian factor involved in the development or maturation of the ovary.
|
