Study of induction mechanism of autophagy using autophagy induction system
| Project/Area Number |
23570241
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
|---|
| Research Field |
Cell biology
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|---|
| Research Institution | National Institute for Basic Biology |
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Principal Investigator |
KAMADA Yoshiaki 基礎生物学研究所, 多様性生物学研究室, 助教 (20291891)
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|---|
| Project Period (FY) |
2011 – 2013
|
| Project Status |
Completed (Fiscal Year 2013)
|
| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 栄養環境 / シグナル伝達 / 出芽酵母 / 生化学 / 細胞生物学 / ラパマイシン / TOR / オートファジー / ＴＯＲ |
|---|
| Research Abstract |
Nutrients are indispensable for life. Thus, perception of the nutrient environment is also essential for cells. To recognize cellular nutrient conditions, eukaryotic cells employ Tor (target of rapamycin) protein kinase. However, it is not clear the mechanism how Tor perceives nutrient signals.
Our research group established a method to monitor Tor activity in vivo. The aim of our research group is to reveal the molecular mechanisms of how Tor receives nutrient signals.
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Report
(4 results)
Research Products
(19 results)
