Study on anteroposterior and dorsoventral axes in echinoderm
| Project/Area Number |
23570248
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Developmental biology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
AKASAKA Koji 東京大学, 理学(系)研究科(研究院), 教授 (60150968)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 棘皮動物 / 体軸 / Hox / 神経系 / 国際情報交換 / 五放射相称 / 前後軸 / 背腹軸 / Hoxクラスター / chordin / BMP2/4 / Pax6 |
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| Research Abstract |
Pentameral symmetry is a characteristic of echinoderms, which do not have a clear anterior-posterior axis and lack head structures. Hox cluster genes are broadly conserved across deuterostomes and protostomes, and are demonstrated a linear cluster structure in the genome. Expression patterns on the anterior-posterior axis are also identical in the ordering of the genes in the genome and in developmental stages, demonstrating a relation to formation patterns along the anterior posterior axis. The spatial expression patterns of crinoid Oxycomanthus japonicus and sea cucumber Apostichopus japonicus were examined. Co-linearity expression of the Hox gene cluster along the axis is not observed in Oxycomanthus japonicus; however the co-linearity expression along the gut in Apostichopus japonicus; which has obvious external anterior posterior axis, is observed. The results imply that the function of Hox cluster genes is different in different groups of echinoderm.
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Report
(4 results)
Research Products
(36 results)
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[Presentation] Analysis of Hox genes of a crinoid, Oxycomanthus japonicus2011
Author(s)
Mariko Kondo, Toko Tsurugaya, Noriko Sumiyoshi, Akihito Omori, Tetsuro Ikuta, Tatsuya Ota, Kazuho Ikeo, Hidetoshi Saiga, Koji Akasaka
Organizer
The Developmental Biology of the Sea Urchin XIX
Place of Presentation
Marine Biological Laboratory Woods Hole, MA 02543, USA
Related Report
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