| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
The fu-2 is a spontaneous and recessive medaka mutant, which exhibits fused centra and the absence of the intervertebral ligaments. As a result of positional cloning analysis, the fu-2 locus was mapped to chromosome23, but it was not identified in the medaka ensemble database. This result indicates that the fu-2 locus is locating on unknown region of choromosomal end. Finally, two candidate genes for the fu-2 phenotype, which relate to the Wnt signaling pathway, were found in this unknown region.
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