Evolutionary mechanisms of regulation of gene expression

• Project/Area Number: 23570274
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Evolutionary biology
• Research Institution: Fukuoka Women's University
• Principal Investigator: INOMATA Nobuyuki 福岡女子大学, 文理学部, 准教授 (20301335)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000); Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
• Keywords: 遺伝子進化 / 遺伝子発現 / ショウジョウバエ

Research Abstract

As amylase gene expression system of Drosophila melanogaster is a model system, I identified 353 candidate genes, which includes genes relating to starch and sugar metabolism, for differential gene expression using RNAseq. Some of the 353 genes were duplicated genes in genome. Interestingly, amino acid sequences of the duplicated copies were predicted to be similar, but the degree of differential gene expression was highly different between the copies.