Research Project
Grant-in-Aid for Scientific Research (C)
This study examined the acetylcholinesterase 1 gene (AChE1) in Plutella xylostella strains with different sensitivities to acephate. Multiple haplotypes of the gene were found in the field-collected strains including distinct haplotypes carrying one or both previously reported mutations (A298S and G324A). Moreover, sequencing results indicated the presence of duplicated copies of the gene in the fieldcollected strains. No correlation was found between copy numbers of AChE1 and levels of resistance to acephate suggesting that extensive AChE1 duplication is not a major resistance factor at least in some P. xylostella strains. Proportions of the A298S and G324A mutations showed no correlation with levels of resistance to acephate. This suggests that acephate resistance of P. xylostella is complex and cannot be evaluated based on the AChE1 copy number or proportions of the resistance mutations alone.
All 2014 2013 2012 2011 Other
All Journal Article (5 results) (of which Peer Reviewed: 4 results, Open Access: 1 results) Presentation (15 results) (of which Invited: 3 results) Book (1 results)
Insect Biochem. Mol. Biol
Volume: 48 Pages: 83-90
Insect Biochemistry and Molecular Biology
10.1016/j.ibmb.2014.02.008
Pestic. Biochem. Physiol.
Volume: 102 Pages: 102-105
Pesticide Biochemistry and Physiology
Volume: 102 Issue: 2 Pages: 142-145
10.1016/j.pestbp.2011.12.005
植物防疫
Volume: 66 Pages: 40-45
40019213154