| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Research Abstract |
In vitro evaluation systems for mitochondrial function of myotubes were developed, and enhancing effects of mitochondrial functions were evaluated. The effectiveness of fermented milk Kefir was revealed. (1) Enhancing effects of energy metabolism in myotubes via activations 5'-AMP-activated protein kinase and acetyl-CoA carboxylase. (2) Enhancing effects of peroxisome proliferator-activated receptor-gamma coactivator-1 alpha expression, which is the key molecule related to mitochondrial biogenesis. (3) Enhancing effects of cellular respiratory activities.
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