Functional profiles of skin mucus in bivalve mollusks involved in a surface barrier against bacterial infection
| Project/Area Number |
23580245
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
General fisheries
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| Research Institution | Tohoku University |
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Principal Investigator |
TAKAHASHI Keisuke 東北大学, (連合)農学研究科(研究院), 准教授 (80240662)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 生体防御 / 二枚貝 / マガキ / 体表面粘液 / 抗菌活性 / リゾチーム / キチナーゼ / 国際研究者交流 / 国際情報交流 / ホタテガイ / 感染 |
|---|
| Research Abstract |
Shellfish belongs to the phylum Mollusca and is mainly comprised of bivalves and gastropods. The Phylum Mollusca is one of the largest and numerous groups in the animal kingdom. Shellfish and microorganisms coexist in the biosphere in numerous ways. Thus, bivalves have evolved sensitive mechanisms for recognizing pathogens and an array of strategies to defend themselves against attacks by microorganisms such as bacteria, fungi, and parasites. An oft-asked question is how invertebrates including shellfish survive against pathogenic microorganisms without an adaptive immune system. Indeed, invertebrates do not have lymphocytes and do not produce antibodies. Thus, we have investigated that skin mucus from mantle and gill functions as a surface barrier against bacterial infection.
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Report
(4 results)
Research Products
(28 results)
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[Journal Article] Molecular characterization and expression analysis of chitinase from the Pacific oyster Crassostrea gigas.2013
Author(s)
Okada, Y., Yamaura, K., Suzuki, T., Itoh, N., Osada, M.and Takahashi, KG.
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Journal Title
Comp. Biochem. Physiol.
Volume: 165B
Issue: 2
Pages: 83-89
DOI
Related Report
Peer Reviewed
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[Presentation] A Peptidoglycan Recognition Protein Induces Hemocyte Degranulation in the Pacific Oyster, Crassostrea gigas2013
Author(s)
Iizuka, M, Nagasaki, T., Takahashi, KG., Osada, M., and Itoh, N.
Organizer
Aquaculture 2013, World Aquaculture Society
Place of Presentation
Nashville, Tennessee, USA
Year and Date
2013-02-25
Related Report
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[Book] Bondad-Reantaso, MG., Jones, JB., Corsin, F., Aoki, T. (eds), Diseases in Asian Aquaculture VII, Fish Health Section, Asian Fisheries Society, Selangor2011
