Influence of early separation from the dams on behavioral developement and its neural mechanism in calf

• Project/Area Number: 23580382
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Zootechnical science/Grassland science
• Research Institution: National Institute of Agrobiological Sciences
• Principal Investigator: YAYOU Ken-ichi (2012-2013) 独立行政法人農業生物資源研究所, 動物生産生理機能研究ユニット, 主任研究員 (40343967)
• Project Period (FY): 2011-04-28 – 2014-03-31
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000); Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: 早期母子分離 / グルーミング / ウシ / 日増体重 / 社会的ストレス / 擬似グルーミング装置 / 行動発達 / オキシトシン / 愛撫処理 / ストレス

Outline of Final Research Achievements

The early maternal deprivation has long-lasting negative effects on growth and behavioral development in several animal species. Though early cow-calf separation has become popular in dairy and even in beef industry, people are less concerned about the negative effect. We have developed a mechanical brush, an automatic rotating brush, for calf as an alternative for mother's grooming (patent-pending) and examined its effects on calves' growth and behavior.
The calves continuously utilized the brush until grouping. The average utilization time per 1 day was 25.3 min. Although the daily weight gains during 3 months after group introduction were not different in female, male calves using the brush gained more weight than control suggesting its appeasing effect for social stress. These data suggest a strong motivation of calves for the usage of the mechanical brush, further research is needed to investigate possible benefits of this device.

Research Products

• [Journal Article] ウシにおける覚醒・睡眠レベルと自律神経緊張度との関連 (2014)
  • Author(s): 渡辺香穂里, 石田三佳, 伊藤秀一, 粕谷悦子, 須藤まどか, 矢用健一
  • Journal Title: Animmal Behaviour and Management Volume: 50
  • NAID: 110009863072
  • Peer Reviewed
• [Journal Article] Relationships of neonatal plasma oxytocin with the behavioral characteristics of cattle introduced into a novel environment (2014)
  • Author(s): Yayou K, Ito S, Yamamoto N
  • Journal Title: Animal Science Journal Volume: 85 Issue: 4 Pages: 481-493
  • DOI: 10.1111/asj.12151
  • Peer Reviewed
• [Journal Article] カリウムと窒素の同時制御による泌乳牛の尿量低減化 (2013)
  • Author(s): 大谷文博, 樋口浩二, 小林洋介, 野中最子, 矢用健一, 須藤まどか
  • Journal Title: 畜産草地研究所研究報告 Volume: 13 Pages: 41-52
  • NAID: 120006587280
  • Peer Reviewed
• [Journal Article] Effects of Intracerebroventricularly Administered Carbetocin on Social Behavior in Holstein Steers (2013)
  • Author(s): Yayou K, Ito S, Kasuya E, Sutoh M, Yamamoto N
  • Journal Title: Journal of Veterinary Medical Science Volume: 75 Issue: 9 Pages: 1147-1152
  • DOI: 10.1292/jvms.12-0560
  • NAID: 130003362192
  • ISSN: 0916-7250, 1347-7439
  • Peer Reviewed
• [Journal Article] L-DOPA attenuates prolactin secretion in response to isolation stress in Holstein steers (2013)
  • Author(s): Kasuya E, Yayou K, Sutoh M (2013) ():.
  • Journal Title: Animal Science Journal Volume: Published Online Early View Issue: 7 Pages: 562-568
  • DOI: 10.1111/asj.12037
  • Peer Reviewed
• [Journal Article] Effects of exposure to plant-derived odorants on behavior and the concentration of stress-related hormones in steers isolated under a novel environment (2013)
  • Author(s): Sutoh M, Ito S, Kasuya E, Yayou K
  • Journal Title: Animal Science Journal Volume: 84(2)
  • Peer Reviewed
• [Journal Article] ジャージー種における搾乳時の後肢動作におよぼす搾乳者の影響 (2012)
  • Author(s): 伊藤秀一, 後藤和, 神鷹孝至, プラダンラジブ, 作本亮介, 岡本智伸, 谷峰人, 山本直幸, 矢用健一
  • Journal Title: 日本暖地畜産学会報 Volume: 55(2)
  • NAID: 130004555654
  • Peer Reviewed
• [Journal Article] Central Administration of Neurokinin B Activates Kisspeptin/NKB Neurons in the Arcuate Nucleus and Stimulates Luteinizing Hormone Secretion in Ewes During the Non-Breeding Season (2012)
  • Author(s): Sakamoto K, Murata K, Wakabayashi Y, Yayou K, Ohkura S, Takeuchi Y, Mori Y, Okamura H.
  • Journal Title: Journal of Reproduction and Development Volume: 58 Issue: 6 Pages: 700-706
  • DOI: 10.1262/jrd.2011-038
  • NAID: 10031146934
  • ISSN: 0916-8818, 1348-4400
  • Peer Reviewed
• [Journal Article] Central regulation of stress response in cattle. (2012)
  • Author(s): Yayou K
  • Journal Title: Japan Agricultural Research Quarterly Volume: 46(1) Pages: 27-34
  • NAID: 130002147965
  • Peer Reviewed
• [Presentation] 早期母子分離牛への母親のケアの代替「擬似グルーミング装置」の利用性とその効果 (2014)
  • Author(s): 矢用健一，小針大助，石田三佳
  • Organizer: 日本畜産学会第118回大会
  • Place of Presentation: つくば国際会議場
• [Presentation] ウシ下垂体前葉細胞における各種遺伝子発現に及ぼすセロトニンの影響 (2014)
  • Author(s): 小林洋介，兼松伸枝，大谷文博，粕谷悦子，矢用健一，須藤まどか
  • Organizer: 日本畜産学会第118回大会
  • Place of Presentation: つくば国際会議場
• [Presentation] ウシ成長ホルモン分泌リズム形成におけるドーパミンの役割 (2014)
  • Author(s): 粕谷悦子, 須藤まどか, 矢用健一
  • Organizer: 日本畜産学会第118回大会講演要旨226
  • Place of Presentation: つくば国際会議場
• [Presentation] Usage of mechanical brush by Japanese Black calves after early separation from their dams (2014)
  • Author(s): Ken-ichi YAYOU, Daisuke KOHARI, Mitsuyoshi ISHIDA
  • Organizer: the 48th Congress of the International Society for Applied Ethology
  • Place of Presentation: Vitoria-Gasteiz, Spain
• [Presentation] The relationship between awake･sleep states and autonomic nervous balance in cattle. (2014)
  • Author(s): Yayou, K., Watanabe, K., Ishida, M., Kasuya, E., Sutoh, M., Ito, S.
  • Organizer: WAFL2014 - 6th International Conference on the Assessment of Animal Welfare at Farm and Group Level
  • Place of Presentation: Clermont-Ferrand, France
• [Presentation] Effect of replacing feed grains by food by-product on energy metabolism of lactating cows (2013)
  • Author(s): Higuchi K, Ohtani F, Kobayashi Y, Nonaka I, Yayou K, Sutoh M, Enishi O
  • Organizer: 4th International Symposium on Energy and Protein Metabolism and Nutrition
  • Place of Presentation: Sacramento, California, USA
• [Presentation] Relationships of social behaviors with neonatal plasma oxytocin in heifer calves (2012)
  • Author(s): Yayo K, Ito S, Yamamoto N
  • Organizer: Proceedings of the 46th Congress of the International Society for Applied Ethology 198
  • Place of Presentation: Viena, Austria
• [Presentation] 去勢子牛におけるオキシトシンおよび長期作用型オキシトシン作用薬鼻腔内投与の効果
  • Author(s): 吉田茉純，須藤まどか，粕谷悦子，桑原正貴，矢用健一
  • Organizer: 日本家畜管理学会・応用動物行動学会合同2014年度春季研究発表会
  • Place of Presentation: つくば研究交流センター
• [Presentation] 産卵鶏の恐怖性に飼育環境と鶏種が及ぼす影響
  • Author(s): 岩原真利, 岡本智伸, 矢用健一, 伊藤秀一
  • Organizer: Animal Behaviour and Management 49(1):38
  • Place of Presentation: 広島市 安田女子大学
• [Presentation] ウシにおける心拍変動解析による安静状態の自律神経緊張度評価
  • Author(s): 渡邉香穂里, 石田三佳, 伊藤秀一, 須藤まどか, 粕谷悦子, 矢用健一
  • Organizer: Animal Behaviour and Management 49(1):40
  • Place of Presentation: 広島市 安田女子大学
• [Patent(Industrial Property Rights)] 子牛の疑似グルーミング装置及び飼育管理方法 (2018)
  • Inventor(s): 矢用 健一
  • Industrial Property Rights Holder: (国研)農研機構
  • Industrial Property Rights Type: 特許
  • Acquisition Date: 2018
• [Patent(Industrial Property Rights)] 子牛の疑似グルーミング装置及び飼育管理方法 (2014)
  • Inventor(s): 矢用健一
  • Industrial Property Rights Holder: （独）農業生物資源研究所
  • Industrial Property Rights Type: 特許
  • Filing Date: 2014