| Project/Area Number |
23590023
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Hokuriku University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KANAME Mamoru 北陸大学, 薬学部, 講師 (70224582)
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| Co-Investigator(Renkei-kenkyūsha) |
MINOURA Mao 立教大学, 理学部, 教授 (30274046)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
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| Keywords | ヘテロ環化学 / イソセレノシアナート / 三重結合 / 求核剤 / ジカルコゲニド / 含セレン複素環 / カルコゲン元素 / 分子内三重結合 / 付加・環化反応 / ジセレニド / ベンゾセレノフェン / ヨウ素環化反応 / ベンゾチアジン / ベンゾセレナジン / ベンゾセレナゾール / セレナジン |
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| Research Abstract |
(1) The cycloaddion of several nucleophiles having a triple bond or an appropriative leaving group with the isoselenocyanates and the relatives was examined. (2) The cycloaddion of the isoselenocyanates having a triple bond (or a leaving group) with some nucleophiles was also carried out. The novel heterocycles containing a chalcogen element (Se, S, Te) were effectively obtained by these two original methods. The application and functionalities (structure and reactivity) were studied. Furthermore, the iodocyclization of these substrates and the nucleophiles was focused to give more functionalized products. The novel iodocyclization of the dichalcogenides was also found to prepare the heterocycles containing a chalcogen element.
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