| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Research Abstract |
alpha-Dystroglycan is an extracellular peripheral membrane glycoprotein, which is essential for the interaction between the cytoskeleton and the extracellular matrix. The important factor of this interaction is considered to be the phosphorylated O-mannosyl glycan on alpha-dystroglycan. In the present study, a synthetic route to the phosphorylated O-mannosyl glycan has been developed. We also developed a method to analyze interactions between oligosaccharides immobilized on microtiter plates and lectins.
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