Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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Research Abstract |
In the present study, we examined the effects of the stress-related catecholamines adrenaline and noradrenaline on the functions of dendritic cells and macrophages. We found adrenoceptor-mediated increase in IL-33, REDD1, and transglutaminase 2 expressions by these cells. Because stress events activate the sympathetic nervous system and result in secretion of the catecholamines, adrenoceptor-mediated increase in these molecules might be associated with stress-related inflammatory disorders.
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