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Control of nosocomial infection with multidrug-resistant Acinetobacter baumannii

Research Project

Project/Area Number 23590614
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical sociology
Research InstitutionJichi Medical University

Principal Investigator

HAYASHI Shunji  自治医科大学, 医学部, 准教授 (40260765)

Co-Investigator(Kenkyū-buntansha) MORISAWA Yuji  自治医科大学, 医学部, 准教授 (70302685)
YOSHIMURA Akio  自治医科大学, 医学部, 助教 (90448845)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywords多剤耐性 / アシネトバクター / 院内感染 / 病院疫学 / 環境調査 / 選択培地 / 感染制御 / 環境汚染
Research Abstract

Multidrug-resistant Acinetobacter baumannii (MDRA) is resistant to many antimicrobials. It is difficult to treat MDRA infection. MDRA contaminates hospital environments, which can cause nosocomial infection. Nosocomial outbreak of MDRA infection occurred at Jichi Medical University Hospital. It is important for the control of nosocomial MDRA infection to find the articles contaminated with MDRA. A hospital epidemiological examination and a bacteriological environmental survey are utilized for finding the contaminated articles. We developed a MDRA-selective medium, which is very useful for investigating MDRA contamination of hospital environments.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (22 results)

All 2014 2013 2012 2011 Other

All Journal Article (10 results) (of which Peer Reviewed: 5 results) Presentation (11 results) Remarks (1 results)

  • [Journal Article] Comparison of hand hygiene procedures for removing Bacillus cereus2014

    • Author(s)
      Sasahara T, Hayashi S, Hosoda K, Morisawa Y, Hirai Y
    • Journal Title

      Biocontrol Science

      Volume: 19

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A bovine myeloid antimicrobial peptide (BMAP-28) kills methicillin-resistant Staphylococcus aureus but promotes adherence of the bacteria2014

    • Author(s)
      Takagi S, Bai L, Ozeki T, Miyagi H, Kuroda K, Hayashi S, Yoneyama H, Ando T, Isogai E
    • Journal Title

      Animal Science Journal

      Volume: 85 Issue: 3 Pages: 342-346

    • DOI

      10.1111/asj.12109

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Susceptibility difference between methicillin-susceptible and methicillin-resistant Staphylococcus aureus to a bovine myeloid antimicrobial peptide (BMAP-28)2014

    • Author(s)
      Takagi S, Nishimura J, Bai L, Miyagi H, Kuroda K, Hayashi S, Yoneyama H, Ando T, Isogai H, Isogai E
    • Journal Title

      Animal Science Journal

      Volume: 85 Issue: 2 Pages: 174-179

    • DOI

      10.1111/asj.12098

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of procedures for decontaminating ultrasound probes2012

    • Author(s)
      Hayashi S, Koibuchi H, Taniguchi N, Hirai Y
    • Journal Title

      J Med Ultrasonics

      Volume: 39 Issue: 1 Pages: 11-14

    • DOI

      10.1007/s10396-011-0332-9

    • NAID

      10030380242

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Bacillus cereus bacteremia outbreak due to contaminated hospital linens2011

    • Author(s)
      Sasahara T, Hayashi S, Morisawa Y, Sakihama T, Yoshimura A, Hirai Y
    • Journal Title

      Eur J Clin Microbiol Infect Dis

      Volume: 30 Issue: 2 Pages: 219-226

    • DOI

      10.1007/s10096-010-1072-2

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] 病院環境における細菌の生残と院内感染の発生2011

    • Author(s)
      平井義一,笹原鉄平,吉村章,森澤雄司,下村裕史,林俊治
    • Journal Title

      化学療法の領域

      Volume: 27 Pages: 1714-1721

    • Related Report
      2013 Final Research Report
  • [Journal Article] アウトブレイク対策における環境汚染調査2011

    • Author(s)
      吉村章,笹原鉄平,林俊治
    • Journal Title

      クリーンテクノロジー

      Volume: 21 Pages: 26-29

    • Related Report
      2013 Final Research Report 2011 Research-status Report
  • [Journal Article] 多剤耐性アシネトバクター・バウマニ2011

    • Author(s)
      林俊治,吉村章,平井義一
    • Journal Title

      カレントテラピー

      Volume: 29 Pages: 12-17

    • Related Report
      2013 Final Research Report
  • [Journal Article] 多剤耐性アシネトバクター・バウマニ2011

    • Author(s)
      林俊治、吉村章、平井義一
    • Journal Title

      カレントテラピー

      Volume: 29 Pages: 276-281

    • Related Report
      2011 Research-status Report
  • [Journal Article] 多剤耐性アシネトバクターの臨床像と治療のポイント2011

    • Author(s)
      吉村章、林俊治、平井義一
    • Journal Title

      感染と抗菌薬

      Volume: 14 Pages: 149-154

    • Related Report
      2011 Research-status Report
  • [Presentation] 医療スタッフにおける手指衛生と手指芽胞汚染の関係2014

    • Author(s)
      笹原鉄平,菅原香織,渡邉美智代,稲川秀樹,林俊治,森澤雄司,平井義一
    • Organizer
      第29回日本環境感染学会総会・学術集会
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] 病院内の環境細菌調査2014

    • Author(s)
      横田憲治,渡邉都貴子,苔口進,林俊治,平井義一
    • Organizer
      第29回日本環境感染学会総会・学術集会
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] 医療スタッフにおける手指衛生と手指芽胞汚染の関係2014

    • Author(s)
      笹原鉄平、菅原香織、渡邉美智代、稲川秀樹、林俊治、森澤雄司、平井義一
    • Organizer
      第29回日本環境感染学会総会・学術集会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 病院内の環境細菌調査2014

    • Author(s)
      横田憲治、渡邉都貴子、苔口進、林俊治、平井義一
    • Organizer
      第29回日本環境感染学会総会・学術集会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 新鮮凍結血漿(FFP)解凍装置の細菌汚染状況と管理方法の検討2013

    • Author(s)
      稲川秀樹,林俊治,菅原香織,笹原鉄平,森澤雄司,平井義一
    • Organizer
      第28回日本環境感染学会総会・学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-12
    • Related Report
      2013 Final Research Report
  • [Presentation] 新鮮凍結血漿(FFP)解凍装置の細菌汚染状況と管理方法の検討2013

    • Author(s)
      稲川秀樹, 林俊治, 菅原香織, 笹原鉄平, 森澤雄司, 平井義一
    • Organizer
      第28回日本環境感染学会総会
    • Place of Presentation
      横浜
    • Related Report
      2012 Research-status Report
  • [Presentation] Development of a selective medium for detection of multidrug resistant Acinetobacter baumannii2012

    • Author(s)
      Hayashi S, Sasahara T, Inagawa H, Morisawa Y, Hirai Y
    • Organizer
      The 11th East Asian Conference on Infection Control and Prevention
    • Place of Presentation
      Tokyo
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] Bacterial growth in intravenous fluid products2012

    • Author(s)
      Sasahara T, Hayashi S, Hosoda K, Inagawa H, Morisawa Y, Hirai Y
    • Organizer
      The 11th East Asian Conference on Infection Control and Prevention
    • Place of Presentation
      Tokyo
    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Presentation] Bacterial contamination of plasma thawing baths2012

    • Author(s)
      Inagawa H, Hayashi S, Sugawara K, Sasahara T, Morisawa Y, Hirai Y
    • Organizer
      The 11th East Asian Conference on Infection Control and Prevention
    • Place of Presentation
      Tokyo
    • Related Report
      2013 Final Research Report
  • [Presentation] Bacterial contamination of plasma thawing water baths2012

    • Author(s)
      Inagawa H, Hayashi S, Sugawara K, Sasahara T, Morisawa Y, Hirai Y
    • Organizer
      The 11th East Asian Conference on Infection Control and Prevention
    • Place of Presentation
      Tokyo
    • Related Report
      2012 Research-status Report
  • [Presentation] 多剤耐性アシネトバクター・バウマニ検出用選択培地の開発2012

    • Author(s)
      林俊治、笹原鉄平、平井義一
    • Organizer
      第85回日本細菌学会総会
    • Place of Presentation
      長崎ブリックホール(長崎市)
    • Related Report
      2011 Research-status Report
  • [Remarks] 本研究にて開発した「多剤耐性アシネトバクター選択培地」の特許性の評価を、自治医科大学と提携している特許事務所にお願いしたのですが、特許性は乏しいとの回答でした。

    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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