| Project/Area Number |
23590672
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Laboratory medicine
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| Research Institution | Osaka University |
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Principal Investigator |
YORIFUJI Shiro 大阪大学, 医学(系)研究科(研究院), 教授 (80191675)
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| Co-Investigator(Kenkyū-buntansha) |
HIRATA Masayuki 大阪大学, 医学系研究科, 准教授 (30372626)
GOTO Tetsu 大阪大学, 医学系研究科, 助教 (80533801)
YANAGISAWA Takufumi 大阪大学, 医学系研究科, 助教 (90533802)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 脳磁図 / 大脳皮質 / 海馬 / 記憶 / 臨床検査 / 言語記憶 / 非言語記憶 |
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| Research Abstract |
We investigated memory related neuromagnetic responses in cerebrocortical and hippocampal areas for the purpose of development in clinical examaination of memory function with magnetoencephalography. The memory task presentation consists of total 150 images of human faces, Japanese kana-words, patterns, and five minutes later, retrieval task was started with half mixture of already presented and new ones. Neuromagnetic responses were clearly noted in inferior frontal cortex and inferior parietal lobule with right side dominance in faces and left in Japanese words. In hippocampal area, neuromagnetic responses were also noted by elongation of recorded times, and laterality in fuctional dominance was clearly recognized with words and pattern images.
In conclusion, function of memory related brain areas can by measured quantitatively with magnetic encephalography, and our method could be useful in clinical field such as early detection of patients with cognitive impairment.
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