Clinical examination of memory functions with magneto-neurophysiological methods.
| Project/Area Number |
23590672
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Laboratory medicine
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| Research Institution | Osaka University |
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Principal Investigator |
YORIFUJI Shiro 大阪大学, 医学(系)研究科(研究院), 教授 (80191675)
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| Co-Investigator(Kenkyū-buntansha) |
HIRATA Masayuki 大阪大学, 医学系研究科, 准教授 (30372626)
GOTO Tetsu 大阪大学, 医学系研究科, 助教 (80533801)
YANAGISAWA Takufumi 大阪大学, 医学系研究科, 助教 (90533802)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 脳磁図 / 大脳皮質 / 海馬 / 記憶 / 臨床検査 / 言語記憶 / 非言語記憶 |
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| Research Abstract |
We investigated memory related neuromagnetic responses in cerebrocortical and hippocampal areas for the purpose of development in clinical examaination of memory function with magnetoencephalography. The memory task presentation consists of total 150 images of human faces, Japanese kana-words, patterns, and five minutes later, retrieval task was started with half mixture of already presented and new ones. Neuromagnetic responses were clearly noted in inferior frontal cortex and inferior parietal lobule with right side dominance in faces and left in Japanese words. In hippocampal area, neuromagnetic responses were also noted by elongation of recorded times, and laterality in fuctional dominance was clearly recognized with words and pattern images.
In conclusion, function of memory related brain areas can by measured quantitatively with magnetic encephalography, and our method could be useful in clinical field such as early detection of patients with cognitive impairment.
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Report
(4 results)
Research Products
(32 results)
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[Journal Article] Quantitative analysis of phosphenes induced by navigation-guided repetitive transcranial magnetic stimulation2011
Author(s)
Tani N, Hirata M, Motoki Y, Saitoh Y, Yanagisawa T, Goto T, Hosomi K, Kozu A, Kishima H, Yorifuji S, Yoshimine T
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Journal Title
Brain Stimulation
Volume: 4(1)
Pages: 28-37
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[Presentation] Combined use of MEG and TMS to improve the noninvasive evaluation of language dominance2013
Author(s)
Hirata M, Shinshi M, Yanagisawa T, Goto T, Sugata H, Araki T, Hosokawa S, Okamura Y, Hasegawa Y, Ihara A, Yoshimine T, Yorifuji S
Organizer
International Society for the Advancement of Clinical Magnetoencephalography Meeting 2013
Place of Presentation
Sapporo
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[Presentation] 動詞想起課題の言語活動時におけるhighγ帯域の事象関連同期2012
Author(s)
長谷川侑香, 後藤哲, 平田雅之, 柳澤琢史, 石澤望, 菅田陽怜, 荒木俊彦, 細川祥代, 岡村友美子, 進士美沙子, 依藤史郎
Organizer
第42回日本臨床神経生理学会学術大会
Place of Presentation
東京
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[Presentation] 記憶に関する脳磁図計測─記憶に関するスクリーニング検査法をめざして─2012
Author(s)
依藤史郎, 村岡美由紀, 後藤哲, 平田雅之, 柳澤琢史, 岡村友美子, 長谷川侑香, 進士美沙子, 細川祥代, 菅田陽怜, 荒木俊彦
Organizer
第59回日本臨床検査医学会学術集会
Place of Presentation
京都
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