Translational research of animal study and clinical trial for the mechanisms of weather-dependent pain aggravation.
Project/Area Number |
23590710
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Pain science
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Research Institution | Nagoya University |
Principal Investigator |
SATO JUN 名古屋大学, 動物実験支援センター, 教授 (00235350)
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Project Period (FY) |
2011 – 2013
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Project Status |
Completed (Fiscal Year 2013)
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Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
Keywords | 気象変化 / 慢性痛 / 自律神経 / 内耳前庭 / 疼痛 / 気象 / うつ病 / 低温 / 低気圧 |
Research Abstract |
The authors have clarified underlying mechanisms of weather-sensitive diseases in the basic study with animal and subjects. In the present research project, we have further progressed the animal study and had clinical study using chronic pain patients with their pain to be sensitive to weather change. This translational study clarified important roles of inner ear in the mechanism of weather-sensitive condition and provided a scientific link between laboratory research and human trials, and the beginning of discovery of therapeutic strategies for this syndrome.
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Report
(4 results)
Research Products
(62 results)
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[Journal Article] The effect of celiac plexus block on hear rate variability2013
Author(s)
Arai YC P, Morimoto A, Sakurai H, Ohmichi Y, Aono S, Nishihara M, Sato J, Ushida T, Inoue S, Kurisuno M, Kobayashi Y
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Journal Title
Journal of Anesthesia
Volume: 27(1)
Pages: 62-65
DOI
Related Report
Peer Reviewed
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[Journal Article] Neurolytic celiac plexus block reduces occurrence and duration of ter- minal delirium in patients with pancreatic cancer2013
Author(s)
Arai YC P, Nishihara M, Kobayashi K, Kanazawa T, Hayashi N, Tohyama Y, Nishida K, Arakawa M, Suzuki C, Kinoshita A, Kondo M, Matsubara S, Yokoe N, Hayashi R, Ohta A, Sato J, Ushida T
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Journal Title
Journal of Anesthesia
Volume: 27(1)
Pages: 88-92
DOI
Related Report
Peer Reviewed
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[Journal Article] The effect of celiac plexus block on heart rate variability.2013
Author(s)
ARAI Yonng-Chang P, MORIMOTO Atsuko, SAKURAI Hiroki, OHMICHI Yusuke, AONO Shuichi, NISHIHARA Makoto, SATO Jun, USHIDA Takahiro, INOUE Sshinsuke, KURISUNO Makoto, KOBAYASHI Yuji
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Journal Title
Journal of Anesthesia
Volume: 27(1)
Pages: 62-65
DOI
Related Report
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[Journal Article] Treadmill running and static stretching improve long-lasting hyperalgesia, joint limitation, and muscle atrophy induced by cast immobilization in rats.2013
Author(s)
MORIMOTO Atsuko, WINAGA Handriadi, SAKURAI Hiroki, OHMICHI Mika, YOSHIMOTO Takahiko, OHMICHI Yusuke, MATSUI Takuya, USHIDA Takahiro, OKADA Tadashi, SATO Jun
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Journal Title
Neuroscience Letters
Volume: 534
Pages: 295-300
DOI
Related Report
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[Presentation] 薬物依存モデル動物の近視眼的意思決定2013
Author(s)
溝口博之, 福本和哉, 王 天, 佐藤 純, 山田清文
Organizer
第22回神経行動薬理 若手研究者の集い, シンポジウム「次世代に向けての行動薬理学とその新展開」
Place of Presentation
福岡
Year and Date
20130320-20130320
Related Report
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[Presentation] ストレスと痛み2011
Author(s)
佐藤 純
Organizer
第8回宮崎ペインカンファランス(招待講演)
Place of Presentation
宮崎
Year and Date
2011年11月15日
Related Report
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[Presentation] ストレスと痛み2011
Author(s)
佐藤純
Organizer
第8回宮﨑ペインカンファランス
Place of Presentation
宮﨑
Year and Date
2011-11-15
Related Report
Invited
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[Presentation] 自律神経と疼痛2011
Author(s)
佐藤純
Organizer
神戸大学がんプロフェッショナル養成プラン講義
Place of Presentation
神戸
Year and Date
2011-09-08
Related Report
Invited
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