Relationship between breast milk dioxin concentrations and steroid hormone levels in Vietnamese

• Project/Area Number: 23590735
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Hygiene
• Research Institution: Kanazawa University
• Principal Investigator: OKAMOTO Rie 金沢大学, 保健学系, 准教授 (50303285)
• Co-Investigator(Renkei-kenkyūsha): KIDO Teruhiko 金沢大学, 保健学系, 教授 (20167373) ; NAKAGAWA Hideaki 金沢医科大学, 医学部, 教授 (00097437) ; MARUZENI Syoko 金沢大学, 保健学系, 研究員 (50599404)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000); Fiscal Year 2013: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000); Fiscal Year 2012: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: 環境保健 / ダイオキシン / 健康被害

Research Abstract

The purpose of this study was to clarify the association of dioxin in breast milk and steroid hormone in serum and saliva, primiparae's growth by comparing the defoliant sprayed area and non-sprayed area in Vietnam. The subjects were mother aged between 20 and 30 years old and their primiparae aged between 4 and 16 weeks, each 50 pairs.
Almost Dioxin isomer concentrations from sprayed area were higher than non-sprayed area. Dioxin concentrations showed U-shaped relationship with some steroid hormone levels. Girl's growth showed stronger relationship with dioxin concentrations and steroid hormone levels than boy's growth.