A population-based epidemiological study on the association between mild cognitive impairment and atherosclerosis
Project/Area Number |
23590790
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Public health/Health science
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Research Institution | Shiga University of Medical Science |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
UESHIMA Hirotsugu 滋賀医科大学, アジア疫学研究センター, 特任教授 (70144483)
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Co-Investigator(Renkei-kenkyūsha) |
MIURA Katsuyuki 滋賀医科大学, 医学部, 教授 (90257452)
OHKUBO Takayoshi 帝京大学, 医学部, 教授 (60344652)
SHIINO Akihiko 滋賀医科大学, MR医学総合研究センター, 准教授 (50215935)
KADOTA Aya 大阪教育大学, 教育学部, 准教授 (60546068)
TAKASHIMA Naoyuki 滋賀医科大学, 医学部, 特任助教 (80435883)
MIYAGAWA Naoko 滋賀医科大学, アジア疫学研究センター, 特任助手 (20388169)
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Project Period (FY) |
2011 – 2013
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Project Status |
Completed (Fiscal Year 2013)
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Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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Keywords | 軽度認知機能障害 / 一般集団 / 腎機能 / 軽度認知機能低下 / 動脈硬化 / 疫学研究 |
Research Abstract |
The aim of the project is to investigate association of cognitive ability with atherosclerosis-related factors. By the end of fiscal year of 2013 (Mar.2014), we were able to conduct examinations on more participants (751) than initially planned (400). ] Preliminary analysis on 540 participants suggested an association of chronic kidney disease with cognitive decline, which we orally presented in an academic meeting held by the Japan Society of Cardiovascular Disease Prevention (June 15, 2013). We confirmed that there was no evidence of bias according to scorer of the cognitive function test. With further analyses combining more data, we will submit our final result to an academic journal soon.
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Report
(4 results)
Research Products
(65 results)
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[Journal Article] Cross-sectional comparison of coronary artery calcium scores between Caucasian men in the United States and Japanese men in Japan: the multi-ethnic study of atherosclerosis and the Shiga epidemiological study of subclinical atherosclerosis.2014
Author(s)
Fujiyoshi A, Miura K, Ohkubo T, Kadowaki T, Kadowaki S, Zaid M, Hisamatsu T, Sekikawa A, Budoff MJ, Liu K, Ueshima H; SESSA Research Group; MESA Research Group.
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Journal Title
Am J Epidemiol
Volume: 180
Issue: 6
Pages: 590-8
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Particle numbers of lipoprotein subclasses and arterial stiffness among middle-aged men from the ERA JUMP study.2014
Author(s)
Vishnu A, Choo J, Masaki KH, Mackey RH, Barinas-Mitchell E, Shin C, Willcox BJ, El-Saed A, Seto TB, Fujiyoshi A, Miura K, Lee S, Sutton-Tyrrell K, Kuller LH, Ueshima H, Sekikawa A.
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Journal Title
J Hum Hypertens.
Volume: 28
Issue: 2
Pages: 111-117
DOI
Related Report
Peer Reviewed
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[Journal Article] High long-chain n-3 fatty acid intake attenuates the effect of high resting heart rate on cardiovascular mortality risk: A 24-year follow-up of Japanese general population.2014
Author(s)
Hisamatsu T, Miura K, Ohkubo T, Yamamoto T, Fujiyoshi A, Miyagawa N, Kadota A, Takashima N, Okuda N, Yoshita K, Kita Y, Murakami Y, Nakamura Y, Okamura T, Horie M, Okayama A, Ueshima H.
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Journal Title
Related Report
Peer Reviewed
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[Journal Article] Long-chain n-3 polyunsaturated fatty acids intake and cardiovascular disease mortality risk in japanese: a 24-year follow-up of NIPPON DATA80.2014
Author(s)
Miyagawa N, Miura K, Okuda N, Kadowaki T, Takashima N, Nagasawa SY, Nakamura Y, Matsumura Y, Hozawa A, Fujiyoshi A, Hisamatsu T, Yoshita K, Sekikawa A, Ohkubo T, Abbott RD, Okamura T, Okayama A, Ueshima H.
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Journal Title
Atherosclerosis
Volume: 232
Issue: 2
Pages: 384-389
DOI
NAID
Related Report
Peer Reviewed
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[Journal Article] Carotid Intima-Media Thickness and Plaque in Apparently Healthy Japanese Individuals with an Estimated 10-Year Absolute Risk of CAD Death According to the Japan Atherosclerosis Society (JAS) Guidelines 2012: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA).2013
Author(s)
Kadota A, Miura K, Okamura T, Fujiyoshi A, Ohkubo T, Kadowaki T, Takashima N, Hisamatsu T, Nakamura Y, Kasagi F, Maegawa H, Kashiwagi A, Ueshima H.
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Journal Title
J Atheroscler Thromb.
Volume: 20
Pages: 755-766
NAID
Related Report
Peer Reviewed
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[Journal Article] Aortic stiffness and calcification in men in a population-based international study.2012
Author(s)
Sekikawa A, Shin C, Curb JD, Barinas-Mitchell E, Masaki K, El-Saed A, Seto TB, Mackey RH, Choo J, Fujiyoshi A, Miura K, Edmundowicz D, Kuller LH, Ueshima H, Sutton-Tyrrell K.
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Journal Title
Atherosclerosis.
Volume: 222(2)
Issue: 2
Pages: 473-477
DOI
Related Report
Peer Reviewed
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[Journal Article] Long-term risk of BP values above normal for cardiovascular mortality: a 24-year observation of Japanese aged 30 to 92 years.2012
Author(s)
Takashima N, Ohkubo T, Miura K, Okamura T, Murakami Y, Fujiyoshi A, Nagasawa SY, Kadota A, Kita Y, Miyagawa N, Hisamatsu T, Hayakawa T, Okayama A, Ueshima H; NIPPON DATA80 Research Group.
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Journal Title
J Hypertens
Volume: 30(12)
Issue: 12
Pages: 2299-2306
DOI
Related Report
Peer Reviewed
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[Presentation] Lifetime Cigarette Smoking is Associated with Increased Indices of Abdominal Obesity Independent of Body Mass Index : The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA)2014
Author(s)
Akira Fujiyoshi, Katsuyuki Miura, Sayaka Kadowaki, Aya Kadota, Takayoshi Ohkubo, Naoko Miyagawa, Takashi Hisamatsu, Saitoh Yoshino, Sayuki Torii, Itsuko Miyazawa, Kenichi Mitsunami, Hiroshi Maegawa, Kiyoshi Murata, Hirotsugu Ueshima
Organizer
AHA Epidemiology and Prevention/Nutrition, Physical Activity and Metabolism 2014 Scientific Sessions
Place of Presentation
San Francisco,米国
Year and Date
2014-03-19
Related Report
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[Presentation] Relationship Of Plasma Asymmetrical Dimethylarginine To Carotid Intima-media Thickness In General Japanese Population: The ERA-JUMP And The SESSA2014
Author(s)
Shin-ya Nagasawa, Katsuyuki Miura, Akira Fujiyoshi, Aya Kadota, Takayoshi Ohkubo, Takashi Hisamatsu, Sayaka Kadowaki, Naoko Miyagawa, Sayuki Torii, Maryam Zaid, Kamal Masaki, Emma J.M. Barinas-Mitchell, Marrianne H. Bertolet, Rhobert W. Evans, Aiman El-Saed, Lewis H. Kuller, Akira Sekikawa, Hirotsugu Ueshima
Organizer
AHA Epidemiology and Prevention/Nutrition, Physical Activity and Metabolism 2014 Scientific Sessions
Place of Presentation
Hilton San Francisco Union Square, SanFrancisco, 米国
Related Report
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[Presentation] Serum Soy Isoflavones Are Inversely Associated With Coronary Artery Calcification In A Population-based Sample Of 299 Men In Japan2014
Author(s)
Akira Sekikawa,Katsuyuki Miura, Abhishek Vishnu, Akira Fujiyoshi, Rhobert W Evans, Takashi Kadowaki, Daniel Edmundowicz,Takashi Hisamatsu, Vasudha Ahuja, Hiroshi Maegawa, Marianne Bertolet, Kiyoshi Murata, Tomonori Okamura, Emma J Barinas-Mitchell, Yasuyuki Nakamura,Lewis H Kuller, Hirotsugu Ueshima
Organizer
AHA Epidemiology and Prevention/Nutrition, Physical Activity and Metabolism 2014 Scientific Sessions
Place of Presentation
Hilton San Francisco Union Square, SanFrancisco, 米国
Related Report
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[Presentation] Racial Differences In The Progression Of Carotid Intima-media Thickness In Middle-aged Men-the Era Jump Study2014
Author(s)
Vasudha Ahuja, Emma J Barinas-Mitchell, Todd B Seto, Rhobert Evans, Aya Kadota, Samar R El Khoudary, Akira Fujiyoshi, Abhishek Vishnu, Katsuyuki Miura, Bradley J Willcox, Hirotsugu Ueshima, Kamal Masaki, Lewis H Kuller, Akira Sekikawa
Organizer
AHA Epidemiology and Prevention/Nutrition, Physical Activity and Metabolism 2014 Scientific Sessions
Place of Presentation
Hilton San Francisco Union Square, SanFrancisco, 米国
Related Report
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[Presentation] Association of Serum Soy Isoflavones with Metabolic Markers in Japanese Men and Women2014
Author(s)
Rhobert W Evans, Akira Sekikawa,Takashi Kadowaki, Abhishek Vishnu, Sayaka Kadowaki, Aiman El-Saed, Akira Fujiyoshi, Vasudha Ahuja, Tomonori Okamura, Katsuyuki Miura, Lewis H Kuller, Hirotsugu Ueshima
Organizer
AHA Epidemiology and Prevention/Nutrition, Physical Activity and Metabolism 2014 Scientific Sessions
Place of Presentation
Hilton San Francisco Union Square, SanFrancisco, 米国
Related Report
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[Presentation] Relationship of High-density Lipoprotein Cholesterol and Particle Concentrations with Subclinical Carotid Atherosclerosis in Japanese Men2013
Author(s)
Akira Fujiyoshi, Maryam Zaid, Katsuyuki Miura, Tomonori Okamura, NaoyukiTakashima, Sayuki Torii, Yoshino Saito, Takashi Hisamatsu, Naoko Miyagawa, Takayoshi Ohkubo, Aya Kadota, Hiroshi Maegawa, Yasuyuki Nakamura, Kenichi Mitsunami, Hirotsugu Ueshima, For the SESSA Research group
Organizer
第45回日本動脈硬化学会・学術集会
Place of Presentation
東京新宿京王プラザホテル
Year and Date
2013-07-18
Related Report
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[Presentation] 高齢男性における慢性腎臓病と認知機能との関連:滋賀動脈硬化疫学研究2013
Author(s)
藤吉朗, 大久保孝義, 三浦克之, 椎野顕彦, 宮川尚子, 高嶋直敬, 齋藤祥乃, 鳥居さゆ希, 門田文, 門脇紗也佳, 久松隆史, 宮澤伊都子, 上島弘嗣, for the SESSA Research Group
Organizer
第49回日本循環器予防学会・日本循環器管理研究協議会総会
Place of Presentation
石川県金沢市金沢市文化ホール
Year and Date
2013-06-15
Related Report
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[Presentation] 1日のエネルギー摂取量と死亡リスクとの関連:NIPPON DATA802013
Author(s)
永井雅人, 藤吉朗, 大久保孝義, 三浦克之, 奥田奈賀子, 早川岳人, 由田克士, 荒井裕介, 中川秀昭, 中村幸志, 宮川尚子, 高嶋直敬, 門田文, 村上義孝, 岡村智教, 岡山明, 上島弘嗣, NIPPON DATA80研究グループ
Organizer
第49回日本循環器予防学会・日本循環器管理研究協議会総会
Place of Presentation
石川県金沢市金沢市文化ホール
Year and Date
2013-06-14
Related Report
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[Presentation] 生涯非飲酒者における危険因子と栄養摂取の特性:INTERLIPID日本研究2013
Author(s)
宮川尚子, 三浦克之, 藤吉朗, 鳥居さゆ希, 奥田奈賀子, 由田克士, 中川秀昭, 斎藤重幸, 坂田清美, 岡山明, Jeremiah Stamler, 上島弘嗣, INTERMAP-INTERLIPID研究グループ
Organizer
第49回日本循環器予防学会・日本循環器管理研究協議会総会
Place of Presentation
石川県金沢市金沢市文化ホール
Year and Date
2013-06-14
Related Report
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[Presentation] Lifetime Cigarette Smoking is Associated with Increased Indices of Abdominal Obesity Independent of Body Mass Index: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA)
Author(s)
Akira Fujiyoshi, Katsuyuki Miura, Sayaka Kadowaki, Aya Kadota, Takayoshi Ohkubo, Naoko Miyagawa, Takashi Hisamatsu, Saitoh Yoshino, Sayuki Torii, Itsuko Miyazawa, Kenichi Mitsunami, Hiroshi Maegawa, Kiyoshi Murata, Hirotsugu Ueshima,
Organizer
AHA Epidemiology and Prevention/Nutrition, Physical Activity and Metabolism 2014 Scientific Sessions
Place of Presentation
Hilton San Francisco Union Square, SanFrancisco, 米国
Related Report
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[Presentation] Relationship of High-density Lipoprotein Cholesterol and Particle Concentrations with Subclinical Carotid Atherosclerosis in Japanese Men
Author(s)
Akira Fujiyoshi, Maryam Zaid, Katsuyuki Miura, Tomonori Okamura, Naoyuki Takashima, Sayuki Torii, Yoshino Saito, Takashi Hisamatsu, Naoko Miyagawa,Takayoshi Ohkubo, Aya Kadota, Hiroshi Maegawa,Yasuyuki Nakamura, Kenichi Mitsunami, Hirotsugu Ueshima, For the SESSA Research group
Organizer
第45回日本動脈硬化学会・学術集会
Place of Presentation
東京新宿 京王プラザホテル
Related Report
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[Presentation] Lipoprotein Particle Profiles by Nuclear Magnetic Resonance, Standard Lipids and Coronary Artery Calcification in a Japanese General Population: the Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA)
Author(s)
Takashi Hisamatsu, Katsuyuki Miura, Takayoshi Ohkubo, Akira Fujiyoshi, Aya Kadota, Sayaka Kadowaki, Naoko Miyagawa, Sayuki Torii, Yoshino Saitoh, Maryam Zaid, Naoyuki Takashima, Yoshitaka Murakami, Tomonori Okamura, Minoru Horie, Hirotsugu Ueshima
Organizer
第45回日本動脈硬化学会・学術集会
Place of Presentation
東京新宿 京王プラザホテル
Related Report
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[Presentation] Association of Dietary Fatty Acid Intake with Serum High-density Lipoprotein Particle Concentration
Author(s)
Maryam Zaid, Katsuyuki Miura, Akira Fujiyoshi, Akira Okayama, Hideaki Nakagawa, Kiyomi Sakata, Shigeyuki Saito, Nagako Okuda, Nutrition, Katsushi Yoshita, Sohel Choudhury, Beatriz Rodriguez, Kamal Masaki, Bradley Willcox, Naoko Miyagawa, Jeremiah Stamler, Hirotsugu Ueshima
Organizer
AHA Epidemiology and Prevention/Nutrition, Physical Activity and Metabolism 2014 Scientific Sessions
Place of Presentation
Hilton San Francisco Union Square, SanFrancisco, 米国
Related Report
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