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The effects of osteoporosis on the development of atherosclerotic disease in the elderly

Research Project

Project/Area Number 23590833
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Public health/Health science
Research InstitutionTokyo Metropolitan Geriatric Hospital and Institute of Gerontology

Principal Investigator

YOSHIDA Hideyo  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長 (00242735)

Co-Investigator(Renkei-kenkyūsha) SHIMIZU Yoko  東京都健康長寿医療センター研究所, 研究員 (90415505)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2013: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords骨粗鬆症 / 動脈硬化 / 脳卒中 / 心筋梗塞 / 高齢者
Research Abstract

With aging, calcium absorbed from the bone can be easily deposited in the arteries, causing arteriosclerosis. Therefore, we investigated strokes and myocardial infarctions among elderly people who participated in the osteoporosis screening examination. There were a total of 338 participants from the Akita prefecture, and 891 people from Tokyo. As a result, the odds ratio (OR) (and 95% confidence interval) of bone mass (low-to-high value) for new strokes was 1.22 (0.97-1.49) in men, and 1.18 (0.29-2.05) in women. Furthermore, the OR for new ischemic disease was 1.44 (0.63-2.26) in men, and 1.15 (-0.26-2.56) in women. Therefore, there seems to be a greater risk of stroke in men with low bone mass.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (2 results)

All 2014

All Presentation (2 results)

  • [Presentation] 地域在住高齢者における骨粗鬆症(低骨量)が動脈硬化性疾患の発症に及ぼす影響2014

    • Author(s)
      吉田英世, 金憲経, 吉田祐子, 小島成美, 金美芝, 清水容子, 平野浩彦, 鈴木隆雄
    • Place of Presentation
      東京
    • Related Report
      2013 Final Research Report
  • [Presentation] 地域在住高齢者における骨粗鬆症(低骨量)が動脈硬化性疾患の発症に及ぼす影響2014

    • Author(s)
      吉田英世、金 憲経、吉田祐子、小島成美、金 美芝、清水容子、平野浩彦、鈴木隆雄
    • Organizer
      第16回日本骨粗鬆症学会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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