Study of the mechanizum of acute encephalopathy caused by cyanogenic mushroom
Project/Area Number |
23590848
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Legal medicine
|
Research Institution | Hamamatsu University School of Medicine |
Principal Investigator |
GONMORI Kunio 浜松医科大学, 医学部, 特任研究員 (10006744)
|
Co-Investigator(Kenkyū-buntansha) |
SUZUKI Osamu 浜松医科大学, 医学部, 理事 (70093044)
WATANABE Kanako 浜松医科大学, 医学部, 教授 (70288546)
|
Project Period (FY) |
2011 – 2013
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2013: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2012: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2011: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
|
Keywords | きのこ中毒 / 急性脳症 / 青酸 / スギヒラタケ / 培養 / 質量分析 / 代謝 |
Research Abstract |
In autumn 2004, 59 cases of acute encephalopathy were reported across 9 prefectures in Japan.We concluded that encephalopathy experienced caused by was the cyanogenic mushroom.We study the mechanism of the acute encephalopathy by cyanogenic mushroom, Pleurocybella porrigens. For three years from 2011, we collect the mushrooms at a same point.But the occureence of mushroom is not enough except 2012 by unseasonable weather.It is difficult to study with natural materials is affected by the environment such as weather. We tried to artificial cultivation the Pleurocybella porrigens.
|
Report
(4 results)
Research Products
(16 results)
-
[Journal Article] Determination of ibotenic acid and muscimol, the Amanita mushroom toxins, in human serum by liquid chromatography-tandem mass spectrometry2013
Author(s)
Hasegawa K, Gonmori K, Fujita H, Kamijo Y, Nozawa H, Yamagishi I, Minakata K, Watanabe K, Suzuki O
-
Journal Title
Forensic Toxicology
Volume: 31
Issue: 2
Pages: 322-327
DOI
Related Report
Peer Reviewed
-
-
[Journal Article] MALDI-TOF mass spectrometric analysis ofα-amanitin,β-amanitin, and phalloidin in urine2012
Author(s)
Gonmori K, Minakata K, Suzuki M, Yamagishi I, Nozawa H, Hasegawa K, Wurita A,Watanabe K, Suzuki O
-
Journal Title
Forensic Toxicology
Volume: 30(2)
Pages: 179-184
Related Report
-
[Journal Article] A new approach in tandem mass spectrometric simultaneous determination of perchlorate, thiocyanate, and iodide using their ternary complexes with tris(1,10-phenanthroline)iron(II) chelate2012
Author(s)
Minakata K, Nozawa H, Yamagishi I, Gonmori K, Hasegawa K, Suzuki M, Wurita A, Watanabe K, Suzuki O
-
Journal Title
Forensic Toxicology
Volume: 30(2)
Pages: 156-161
NAID
Related Report
-
-
-
-
-
-
[Presentation] MALDI-Q-TOF mass spectrometric determination of alpha-amanitin, beta-amanitin, and phalloidin in urine2013
Author(s)
Gonmori K, Minakata K, Suzuki M, Hasegawa K, Yamagishi I, Nozawa H, Wurita A, Watanabe K, Suzuki O
Organizer
The 51th Annual Meeting of the International Association of Forensic Toxicologists 2013
Place of Presentation
Funchal, Madeira, Portugal
Related Report
-
[Presentation] Maldi-Q-Tof Mass Spectrometric Determination of alpha-amanitin, beta amanitin, and phalloidin in urine2013
Author(s)
Gonmori K, Minakata K, Suzuki M, Hasegawa K, Yamagishi I, Nozawa H, Wurita A, Watanabe K, Suzuki O
Organizer
The 51th Annual Meeting of The International Association of Forensic Toxicologists
Place of Presentation
Funchal, Madeira, Portugal
Related Report
-
-
-
-
-