Inhibitory effect of drinking alcohol on restoration of spontaneous circulation by CPR in injured patients and its mechanism
| Project/Area Number |
23590852
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Legal medicine
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| Research Institution | Kochi University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
FURUMIYA Jyunichi 高知大学, 教育研究部医療学系, 助教 (60363280)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 心肺蘇生法 / 飲酒 / 心拍再開 / 法医解剖 / マグヌス法 / 飲酒傷病者 / 救急医学 / 救急病態病理学 / アルコール / トランスレーショナルリサーチ / 病態薬理学 / 病態病理学 / 薬理学 |
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| Research Abstract |
To investigate whether drinking alcohol has inhibitory effects on the ability of arrested heart to exhibit restoration of spontaneous circulation by cardiopulmonary resuscitation (CPR), the medical records and forensic autopsy findings of patients who died after receiving CPR were examined retrospectively. Restoration of spontaneous circulation was not observed in the patients under the influence of drinking alcohol. Although the investigated numbers are small and further research is needed, our investigation suggests that ethanol may inhibit restoration of spontaneous circulation by CPR in patients with cardiac arrest. Such a tendency was observed in animal experiments of examining restoration of heat beats by reheating after the cessation of heat beats by cooling.
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Report
(4 results)
Research Products
(12 results)
