Objective evaluation of the effect that malnutrition of anorexia nervosa causes to cerebral, digestion , metabolic function
Project/Area Number |
23590884
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
General internal medicine (including Psychosomatic medicine)
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Research Institution | Kyushu University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
KUBO Chiharu 九州大学病院, 院長 (80117100)
YOSHIURA Takashi 九州大学病院, 放射線科, 准教授 (40322747)
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Co-Investigator(Renkei-kenkyūsha) |
TOBIMATSU Shozo 九州大学, 体情報科学講座脳神経生理学, 教授 (40164008)
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Project Period (FY) |
2011 – 2013
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Project Status |
Completed (Fiscal Year 2013)
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Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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Keywords | 神経性食欲不振症 / 低栄養状態 / 脳機能検査 / 脳波 / 体組成 / 中鎖脂肪酸 / fMRI / 栄養療法 / 脳機能 / 緊急入院 / 代謝 / 摂食関連ペプチド |
Research Abstract |
We made the score table which assessed electroencephalographic(EEG) data of the anorexia nervosa (AN) using Fourier transfer objectively.Using fMRI study at the closed eyes rest, we proved that the activity changes in posterior cingulatecortex (PCC) and medial prefrontal cortex (MPFC) during nutrition therapy in the AN. This may catch a characteristic of AN developing for overeating at relax. For anorexia nervosa (AN), in the case of an malnutrition state with Body mass index (BMI) 12kg/m2 or less, the energy supply at starvation shifts from fat store to the catabolism of the muscle and internal organs tissue. This state leads to a physical crisis.
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Report
(4 results)
Research Products
(34 results)
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[Journal Article] The outcome of Japanese anorexia nervosa patients treated with an inpatient therapy in an internal medicine unit2012
Author(s)
N. Amemiya, M. Takii , T. Hata, C. Morita , S. Takakura , K. Oshikiri, H. Urabe, S.Tokunaga, T.Nozaki, K.Kawai, N. Sudo,and C. Kubo
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Journal Title
Eat.Weight Disord
Volume: 17
Related Report
Peer Reviewed
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[Journal Article] The longitudinal BMI pattern and body composition of patients with anorexia nervosa who require urgent hospitalization : A case control study2011
Author(s)
K Kawai, S Yamashita, T Yamanaka, M Gondo, C Morita, T Nozaki, S Takakura, T Hata, Y Yamada, S Matubayashi, M Takii, C Kubo, N Sudo
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Journal Title
BioPsychoSocial Medicine
Volume: 5
Pages: 14-14
NAID
Related Report
Peer Reviewed
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