Effects of Green Tea Gargling on the Prevention of Influenza Infection in High School Students
| Project/Area Number |
23590887
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
General internal medicine (including Psychosomatic medicine)
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| Research Institution | University of Shizuoka |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | インフルエンザ / うがい / 学校保健 / 高校生 / 緑茶 |
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| Research Abstract |
The anti-influenza virus activity of green tea components has been demonstrated in experimental studies. To clarify the effects of green tea gargling on influenza infection, a randomized, 2-group parallel study of 757 high school students conducted for 90 days. The green tea gargling group gargled 3 times a day with bottled green tea, and the water gargling group did the same with tap water. Multivariate logistic regression indicated no significant difference in the incidence of laboratory-confirmed influenza between the green tea group (19 participants; 4.9%) and the water group (25 participants; 6.9%) (adjusted OR, 0.69; 95%CI, 0.37 to 1.28; P = 0.24). The adherence rate among high school students was lower than expected. Among high school students, gargling with green tea was not significantly more efficacious than gargling with water. In order to adequately assess the effectiveness of such gargling, additional large-scale randomized studies are needed.
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Report
(4 results)
Research Products
(44 results)
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[Journal Article] Anti-stress effect of theanine on students during pharmacy practice : Positive correlation among salivaryα-amylase activity, trait anxiety and subjective stress2013
Author(s)
Unno K, Tanida N, Ishii N, Yamamoto H, Iguchi K, Hoshino M, Takeda A, Ozawa H, Ohkubo T, Juneja LR, Yamada H
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Journal Title
Pharmacol Biochem Behav
Volume: 111
Pages: 128-135
DOI
Related Report
Peer Reviewed
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[Journal Article] Anti-stress effect of theanine on students during pharmacy practice: Positive correlation among salivary α-amylase activity, trait anxiety and subjective stress.2013
Author(s)
Unno K, Tanida N, Ishii N, Yamamoto H, Iguchi K, Hoshino M, Takeda A, Ozawa H, Ohkubo T, Juneja LR, Yamada H
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Journal Title
Pharmacol Biochem Behav
Volume: 111
Pages: 128-135
Related Report
Peer Reviewed
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[Journal Article] Influence of the Slow Infusion of a Soybean Oil Emulsion on Plasma Cytokines and Ex Vivo T Cell Proliferation After an Esophagectomy.2013
Author(s)
Yoshiyuki Kagawa, Toshio Maeda, Yasuhiro Kato, Iori Ueda, Tomoko Kudo, Naoe Watanabe, Midori Kimura, Sato Minami, Tatsuichiro Sakamoto, Hiroshi Yamada, Masakazu Takagi.
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Journal Title
JPEN J Parenter Enteral Nutr
Volume: 37(1)
Issue: 1
Pages: 123-8
DOI
Related Report
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[Journal Article] Effects of short-term consumption of a large amount of tea catechins on chromosomal damage, oxidative stress markers, serum lipid, folic acid, and total homocysteine levels : a randomized, double-blind, controlled study2012
Author(s)
Yoshikawa T, Yamada H, Matsuda K, Niino H, Sagesaka YM. Kakuda T, Toyoizumi K, Matsumoto K, Kosuge K, Uchida S, Onoue S, Yamada S, Umegaki K
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Journal Title
Jpn J Clin Pharmacol Ther
Volume: 43(1)
Pages: 9-16
NAID
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[Journal Article] A single nucleotide polymorphism of reduced folate carrier 1 predicts methotrexate efficacy in Japanese patients with rheumatoid arthritis2012
Author(s)
Hayashi H, Tazoe Y, Tsuboi S, Horino M, Morishita M, Arai T, Ohshima M, Matsuyama T, Kosuge K, Yamada H, Tsuji D, Inoue K, Itoh K
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Journal Title
Drug Metab Pharmacokinet
Volume: 28
Pages: 164-168
NAID
Related Report
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[Journal Article] Effects of short-term consumption of a large amount of tea catechins on chromosomal damage, oxidative stress markers, serum lipid, folic acid, and total homocysteine levels: a randomized, double-blind, controlled study.2012
Author(s)
Yoshikawa T, Yamada H, Matsuda K, Niino H, Sagesaka YM. Kakuda T, Toyoizumi K, Matsumoto K, Kosuge K, Uchida S, Onoue S, Yamada S, Umegaki K.
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Journal Title
Jpn J Clin Pharmacol Ther
Volume: 43
Pages: 9-16
NAID
Related Report
Peer Reviewed
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