| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Research Abstract |
e investigated whether Japanese traditional medicine, Hainosankyuto affect the cure of MRSA severe infection disease. In two-dimensional electrophoresis analysis, we found that the amount of extra virulent proteins from MRSA in LB with Hainosankyuto were decreased compared to those in LB. We also found the significant improvement of survival rate and cutaneous ulcer formation in Hainosankyuto-treated mouse after MRSA subcutaneous infection. Furthermore we confirmed that the phagocytosis ability of mouse peritoneal macrophage treated with Hainosankyuto was significantly greater than that without it. We suggested that Hainosankyuto is the candidate of novel anti- MRSA infectious treatment.
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