| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Research Abstract |
We evaluated the expressions of micro satellite instability (BAT26) and mitochondria DNA between the surface and the deeper site of submucosal invasive early gastric cancers, which were indication of non-curative after endoscopic resection. However, there was no significant difference of these molecular markers' expression between these sites (no heterogeneity). These data suggested that it is not clinically usefulness to predict lymph node metastasis from the biopsy specimen of submucosal invasive gastric cancer using molecular marker.
The incidence of lymph node metastasis of submucosal invasive undifferentiated-type early gastric cancers was high regardless of their clinicopathologic factors. The expanded criteria (ulcer-negative, intramucosal cancer 20mm or less without lymphovascular invasion)of endoscopic resection for undifferentiated-type early gastric cancer was pertinent based on long-term outcomes.
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