Evaluation by the molecular biological method of the complications for Colorectal endoscopic submucosal dissection.
| Project/Area Number |
23591023
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Gastroenterology
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| Research Institution | Juntendo University |
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Principal Investigator |
OSADA Taro 順天堂大学, 医学部, 准教授 (00338336)
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| Co-Investigator(Kenkyū-buntansha) |
SAKAMOTO Naoto 順天堂大学, 医学部, 准教授 (10420845)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 大腸腫瘍 / 内視鏡治療 / 菌血症 / 合併症 / 大腸内視鏡 / S-O Clip / Loop Clip / 大腸ESD |
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| Research Abstract |
We examined the incidence of and factors associated with fever, as well as the frequency of bacteremia, in patients with colorectal ESD. The incidence of post-ESD fever in the entire cohort was 46.7%. Multivariate analysis for post-ESD fever found that age and lesion size were closely associated. Bacteria were not detectable.
We evaluate the efficacy of traction device-assisted ESD. Patients were randomized into two groups. The mean procedure time for the S-O clip-assisted ESD group (n=27) was significantly shorter than for the conventional ESD group (n=23).
We evaluate how long the endoscopic clips exert an effect on closure of mucosal defects after ESD. At one week after ESD (n=7), there were clips that were still attached at the repaired lesions in five patients. The defect area indicated a reduction of about 78.8%. At four weeks after ESD (n=7), only one or two clips were still attached at the repaired lesions in two patients. The defect area showed a reduction of about 99.8%.
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Report
(4 results)
Research Products
(44 results)
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[Journal Article] Traction device to remove an adenoma in the appendiceal orifice by endoscopic submucosal dissection2013
Author(s)
Takeda T, Murakami T, Sakamoto N, Goto SP, Ritsuno H, Ueyama H, Mori H, Matsumoto K, Shibuya T, Osada T, Nagahara A, Ogihara T, Watanabe S
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Journal Title
Endoscopy
Volume: 45 Suppl
Related Report
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[Journal Article] Development and clinical usability of a new traction device "medical ring" for endoscopic submucosal dissection of early gastric cancer2013
Author(s)
Matsumoto K, Nagahara A, Ueyama H, Konuma H, Morimoto T, Sasaki H, Hayashi T, Shibuya T, Sakamoto N, Osada T, Ogihara T, Yao T, Watanabe S
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Journal Title
Surg Endosc
Volume: 27
Pages: 3444-51
Related Report
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[Journal Article] Development and clinical usability of a new traction device "medical ring" for endoscopic submucosal dissection of early gastric cancer.2013
Author(s)
Matsumoto K, Nagahara A, Ueyama H, Konuma H, Morimoto T, Sasaki H, Hayashi T, Shibuya T, Sakamoto N, Osada T, Ogihara T, Yao T, Watanabe S.
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Journal Title
Surg Endosc.
Volume: 27(9):3444-51
Issue: 9
Pages: 3444-51
DOI
Related Report
Peer Reviewed
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[Journal Article] The relationship between physical activity level and completion rate of small bowel examination in patients undergoing capsule endoscopy2012
Author(s)
Shibuya T, Mori H, Takeda T, Konishi M, Fukuo Y, Matsumoto K, Beppu K, Sakamoto N, Osada T, Nagahara A, Otaka M, Ogihara T, Watanabe S
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Journal Title
Intern Med
Volume: 51
Pages: 997-1001
NAID
Related Report
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[Journal Article] Endoscopic mucosal resection using a cap-fitted panendoscope as a diagnostic procedure in a case of scirrhous gastric carcinoma2012
Author(s)
Kodani T, Osada T, Matsumoto K, Kato J, Higashihara Y, Morimoto T, Ogata C, Taniguchi G, Mizui T, Matsumura Y, Yoshizawa T, Nagahara A, Mitomi H, Yao T, Watanabe S
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Journal Title
Dig Endosc
Volume: 24
Pages: 190-190
Related Report
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[Journal Article] The 'Loop Clip' is useful for closing large mucosal defects after colorectal endoscopic submucosal dissection : a preliminary clinical study2011
Author(s)
Mori H, Sakamoto N, Osada T, Ritsuno H, Hidaka Y, Nakae K, Matsumoto K, Beppu K, Shibuya T, Yoshizawa T, Nagahara A, Otaka M, Ogihara T, Arai F, Watanabe S
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Journal Title
Dig Endosc
Volume: 23
Pages: 330-1
Related Report
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[Journal Article] Advanced colorectal cancer with double-hump camel-like appearance2011
Author(s)
Ritsuno H, Sakamoto N, Mitomi H, Namihisa A, Mori H, Nakae K, Matsumoto K, Beppu K, Shibuya T, Osada T, Nagahara A, Otaka M, Terai T, Ogihara T, Yao T, Watanabe S
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Journal Title
Dig Endosc
Volume: 23
Pages: 329-329
Related Report
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[Journal Article] Successful endoscopic mucosal resection of a solitary extramedullary plasmacytoma in the sigmoid colon2011
Author(s)
Kodani T, Osada T, Terai T, Ohkusa T, Shibuya T, Sakamoto N, Beppu K, Kato J, Nagahara A, Watanabe H, Watanabe S
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Journal Title
Endoscopy
Volume: 43 Suppl
Related Report
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[Journal Article] Frequent occurrence of fever in patients who have undergone endoscopic submucosal dissection for colorectal tumor but bacteremia is not a significant cause
Author(s)
Izumi K, Osada T, Sakamoto N, Kodani T,Higashihara Y, Ritsuno H, Shibuya T, Nagahara A, Ogihara T, Kikuchi K, Watanabe S
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Journal Title
Surg Endosc
Volume: (in press)
Related Report
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[Journal Article] Prospective clinical trial of traction device-assisted endoscopic submucosal dissection of large superficial colorectal tumors using the S-O clip
Author(s)
Ritsuno H,Sakamoto N Osada T, Goto S, Murakami T,Ueyama H,Mori H, Matsumoto K, Beppu K,Shibuya T, Nagahara A, Ogihara T, Watanabe S
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Journal Title
Surg Endosc
Volume: (in press)
Related Report
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