Identification of coronary vulnerable plaques and effects of intravenous atrial natriuretic peptide on coronary vasodilation using magnetic resonance imaging
| Project/Area Number |
23591057
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Osaka City University |
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Principal Investigator |
EHARA SHOICHI 大阪市立大学, 医学(系)研究科(研究院), 講師 (90382150)
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| Project Period (FY) |
2011-04-28 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2011: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 急性冠症候群 / 血栓 / 核磁気共鳴画像 / 光干渉断層像 / 不安定プラーク / 冠動脈 / 動脈硬化 |
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| Outline of Final Research Achievements |
As acute myocardial infarction (AMI) or cerebral infarction (CI) frequently occurs as the first symptom, screening of the patients with unstable plaque is important for prevention of the onset of AMI or CI. We reported that coronary artery hyperintense plaques on magnetic resonance imaging (MRI) are associated with a unstable plaque morphology. Furthermore, we showed using MRI that the effect of atrial natriuretic peptide on the coronary artery vasodilation was not inferior to those of nitroglycerin, with no significant alteration in heart rate.
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Report
(5 results)
Research Products
(21 results)
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[Journal Article] The strain pattern, and not Sokolow-Lyon electrocardiographic voltage criteria, is independently associated with anatomic left ventricular hypertrophy2014
Author(s)
Ehara S, Hasegawa T, Matsumoto K, OtsukaY, Yamazaki T, Iguchi T, Izumi Y, Shimada K, Yoshiyama M
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Journal Title
Heart Vessels
Volume: 29
Issue: 5
Pages: 638-644
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Insulin resistance is associated with coronary plaque vulnerability: insight from optical coherence tomography analysis2014
Author(s)
Iguchi T, Hasegawa T, Otsuka K, Matsumoto K, Yamazaki T, Nishimura S, Nakata S, Ehara S, Kataoka T, Shimada K, Yoshiyama M
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Journal Title
Eur Heart J Cardiovasc Imaging
Volume: 15
Issue: 3
Pages: 284-291
DOI
Related Report
Peer Reviewed
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[Journal Article] Detailed observation of arterial healing after stent implantation in swine arteries by using optical coherence tomography2012
Author(s)
Satoshi Nishimura, Toru Kataoka, Takao Hasegawa, Yoshiki Kobayashi, Koichiro Asawa, Shinji Nakata, Shoichi Ehara, Akihisa Hanatani, Kenei Shimada, Takashi Muro, Minoru Yoshiyama
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Journal Title
Osaka City Med J
Volume: 58
Pages: 1-11
NAID
Related Report
Peer Reviewed
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[Presentation] Intraluminal and Intrawall Hyperintense Plaques Identified by Noncontrast T1-weighted Magnetic Resonance Imaging Showed Different Vulnerable Plaque Morphology Assessed by Optical Coherence Tomography2013
Author(s)
Matsumoto K, Ehara S, Hasegawa T, Sakaguchi M, Inanami H, Otsuka K, Yamazaki T, Iguchi T, Shimada K, Yoshiyama M
Organizer
American Heart Association
Place of Presentation
Dallas, USA
Related Report
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