| Project/Area Number |
23591064
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Iwate Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
中澤 学 東海大学, 医学部, 講師 (30564702)
松陰 崇 東海大学, 医学部, 准教授 (30445663)
伊苅 裕二 東海大学, 医学部, 教授 (70271567)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | 臨床血管学 / 臨床心臓学 / 国際研究者交流 |
|---|
| Research Abstract |
Treatment of coronary chronic total occlusion (CTO) is the biggest challenge of percutaneous coronary intervention (PCI). However, both clinical data and development of devices that alter treatment success rates are very limited. Accordingly, we performed 1) analyses of clinical data of CTO-PCI, 2) investigation of anatomy of CTO vessels for improvement of success rates, and 3) development of a prototype of dedicated device.
1) Using treatment of 525 CTO lesions, long-term clinical outcomes and substantial effects of initial lesion difficulty on the long-term patency rates were clarified. 2) Distribution of coronary calcification that strongly affects treatment success rates is under investigation by optical coherence tomography. 3) Development of 20 MHz alley ultrasound transducer which can be mounted on the tip of catheter was completed.
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