Molecular imaging of vascular inflammation in patients with coronary artery disease

• Project/Area Number: 23591072
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Circulatory organs internal medicine
• Research Institution: Kurume University
• Principal Investigator: NOBUHIRO TAHARA 久留米大学, 医学部, 講師 (10320186)
• Co-Investigator(Kenkyū-buntansha): ISHIBASHI Masatoshi 久留米大学, 医学部, 教授 (20168256)
• Co-Investigator(Renkei-kenkyūsha): KODAMA Norihiro 久留米大学, 医学部, 助教 (50569382) ; UENO Takafumi 久留米大学, 医学部, 教授 (90184952) ; MITSUTAKE Yoshiaki 久留米大学, 医学部, 助教 (90511874) ; KAIDA Hayato 久留米大学, 医学部, 助教 (40299425)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000); Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: FDG-PET / 多列化CT / 炎症 / 冠動脈ステント / 冠動脈

Research Abstract

We investigated whether FDG activity in coronary arteries implanted bare-metal stent or drug-eluting stent evaluated by FDG-PET/CT angiography is associated with the post-stenting complications. Intense myocardial FDG uptake hampers to evaluate FDG activity in coronary artery lesions. We could not completely suppress the intense myocardial FDG uptake even with at least 12 hour-fasting and heparin loading prior to PET scan. FDG uptake in the stented coronary artery after stenting was associated with the post-stenting complications such as re-stenosis, endothelial dysfunction, mal-apposition, and stent thrombosis.

Research Products

• [Journal Article] Mobile left atrial round mass free floating in mitral regurgitation flow mimicking a whale spray. (2014)
  • Author(s): Tahara A, Tahara N, Honda A, Imaizumi T.
  • Journal Title: BMJ Case Rep. Volume: in press Pages: bcr2013202725-bcr2013202725
  • DOI: 10.1136/bcr-2013-202725
  • Peer Reviewed
• [Journal Article] Pigment epithelium-derived factor improves metabolic derangements and ameliorates dysregulation of adipocytokines in obese type 2 diabetic rats. (2014)
  • Author(s): Matsui T, Nishino Y, Ojima A, Maeda S, Tahara N, Yamagishi S.
  • Journal Title: Am J Pathol. Volume: 184(4) Issue: 4 Pages: 1094-103
  • DOI: 10.1016/j.ajpath.2013.12.032
  • Peer Reviewed
• [Journal Article] Change in serum PEDF level after pioglitazone treatment is independently correlated with that in HOMA-IR. (2014)
  • Author(s): Tahara N, Matsui T, Yamagishi S.
  • Journal Title: Int J Cardiol. Volume: 172(1) Issue: 1 Pages: 244-6
  • DOI: 10.1016/j.ijcard.2013.12.289
  • Peer Reviewed
• [Journal Article] 2-deoxy-2-[18F]fluoro-D-mannose positron emission tomography imaging in atherosclerosis. (2014)
  • Author(s): Tahara N, Mukherjee J, de Haas HJ, Petrov AD, Tawakol A, Haider N, Tahara A, Constantinescu CC, Zhou J, Boersma HH, Imaizumi T, Nakano M, Finn A, Fayad Z, Virmani R, Fuster V, Bosca L, Narula J.
  • Journal Title: Nat Med. Volume: 20(2) Issue: 2 Pages: 215-9
  • DOI: 10.1038/nm.3437
  • Peer Reviewed
• [Journal Article] Molecular imaging of vascular inflammation (2014)
  • Author(s): Tahara N, Tahara A, Honda A, Nitta Y, Kodama N, Yamagishi S, Imaizumi T
  • Journal Title: Curr Pharm Des Volume: 20(14) Pages: 2439-2447
  • URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=Tahara+N
  • Peer Reviewed
• [Journal Article] Molecular imaging of vascular inflammation. (2014)
  • Author(s): Tahara N, Tahara A, Honda A, Nitta Y, Kodama N, Yamagishi S, Imaizumi T.
  • Journal Title: Curr Pharm Des. Volume: 20(14) Pages: 2439-47
  • Peer Reviewed
• [Journal Article] Non-invasive evaluation of bone-forming activity within the calcified atherosclerotic lesions by 99mTc-HMDP scintigraphy. (2014)
  • Author(s): Tahara N, Tahara A, Honda A, Nitta Y, Igata S, Nakamura Y, Takeuchi Y, Akashi H, Tanaka H, Morioka M, Narula J, Yamagishi S, Fukumoto Y
  • Journal Title: JACC Cardiovasc Imaging. Volume: in press
  • Peer Reviewed
• [Journal Article] Pioglitazone decreases coronary artery inflammation in impaired glucose tolerance and diabetes mellitus: evaluation by FDG-PET/CT imaging. (2013)
  • Author(s): Nitta Y, Tahara N, Tahara A, Honda A, Kodama N, Mizoguchi M, Kaida H, Ishibashi M, Hayabuchi N, Ikeda H, Yamagishi S, Imaizumi T.
  • Journal Title: JACC Cardiovasc Imaging. Volume: 6(11) Issue: 11 Pages: 1172-82
  • DOI: 10.1016/j.jcmg.2013.09.004
  • Peer Reviewed
• [Journal Article] Statin therapy resolves coronary artery inflammation. (2013)
  • Author(s): Tahara N, Tahara A, Narula J, Imaizumi T.
  • Journal Title: JACC Cardiovasc Imaging. Volume: 6(10) Issue: 10 Pages: 1119-20
  • DOI: 10.1016/j.jcmg.2013.02.013
  • Peer Reviewed
• [Journal Article] Effects of pioglitazone on visceral fat metabolic activity in impaired glucose tolerance or type 2 diabetes mellitus (2013)
  • Author(s): Kodama N, Tahara N, Tahara A, Honda A, Nitta Y, Mizoguchi M, Kaida H, Ishibashi M, Abe T, Ikeda H, Narula J, Fukumoto Y, Yamagishi S, Imaizumi T
  • Journal Title: J Clin Endocrinol Metab Volume: 98(11) Issue: 11 Pages: 4438-45
  • DOI: 10.1210/jc.2013-2920
  • Peer Reviewed
• [Journal Article] Pioglitazone decreases asymmetric dimethylarginine levels in patients with impaired glucose tolerance or type 2 diabetes. (2013)
  • Author(s): Tahara N, Yamagishi S, Mizoguchi M, Tahara A, Imaizumi T.
  • Journal Title: Rejuvenation Res. Volume: 16(5) Issue: 5 Pages: 344-51
  • DOI: 10.1089/rej.2013.1434
  • Peer Reviewed
• [Journal Article] Serum levels of advanced glycation end products(AGEs) are independently correlated with circulating levels of dipeptidyl peptidase-4 (DPP-4) in humans. (2013)
  • Author(s): TaharaN,Yamagishi,TakeuchiM(3/8)et・al.
  • Journal Title: Clin, Biochem Volume: 46 Issue: 4-5 Pages: 300-303
  • DOI: 10.1016/j.clinbiochem.2012.11.023
  • Peer Reviewed
• [Journal Article] Asymmetrical dimethylarginine level is independently associated with circulating levels of RAGE and PEDF. (2013)
  • Author(s): Tahara N, Yamagishi S, Tahara A, Takeuchi M, Imaizumi T.
  • Journal Title: Int J Cardiol. Volume: 167(6) Issue: 6 Pages: 3072-4
  • DOI: 10.1016/j.ijcard.2012.11.070
  • Peer Reviewed
• [Journal Article] Impact of ischemia-guided initial diagnosis in patients with stable angina (2012)
  • Author(s): Tahara N
  • Journal Title: Circ J Volume: 76(12) Pages: 2742-2743
  • NAID: 10031126041
  • URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=Tahara+N
  • Peer Reviewed
• [Journal Article] Positive association between serum level of glyceraldehyde-derived advanced glycation end products (AGEs) and vascular inflammation evaluated by18F-fluorodeoxy- glucose positron emission tomography (FDG-PET). (2012)
  • Author(s): Tahara N, Yamagishi S, Takeuchi M
  • Journal Title: Diabetes Care Volume: 35 Issue: 12 Pages: 2618-2625
  • DOI: 10.2337/dc12-0087
  • Peer Reviewed
• [Journal Article] Serum levels of pigment epithelium-derived factor, a novel marker of insulin resistance, are independently associated with fasting apolipoprotein B48 levels in humans (2012)
  • Author(s): Nobuhiro Tahara
  • Journal Title: Clin. Biochem. Volume: 45 Issue: 16-17 Pages: 1404-1408
  • DOI: 10.1016/j.clinbiochem.2012.07.095
  • Peer Reviewed
• [Journal Article] Adiponectin is inversely associated with ratio of serum levels of AGEs to sRAGE and vascular inflammation. (2012)
  • Author(s): Nobuhiro Tahara
  • Journal Title: Int. J. Cardiol. Volume: 158 Issue: 3 Pages: 461-462
  • DOI: 10.1016/j.ijcard.2012.05.015
  • Peer Reviewed
• [Journal Article] Molecular imaging of human ACE-1 expression in transgenic rats. (2012)
  • Author(s): Dilsizian V, Zynda TK, Petrov A, Ohshima S, Tahara N, Haider N, Donohue A, Aras O, Femia FJ, Hillier SM, Joyal JL, Wong ND, Coleman T, Babich JW, Narula J.
  • Journal Title: JACC: Cardiovascular Imaging Volume: 5(4) Issue: 4 Pages: 409-18
  • DOI: 10.1016/j.jcmg.2011.10.008
  • Peer Reviewed
• [Journal Article] Successful shunt closure and improvement of hemodynamics in an ASD patient with severe pulmonary arterial hypertension and small shunt following a long-term use of bosentan. (2012)
  • Author(s): Tahara N, Mizoguchi M, Honda A, Tahara A, Nitta Y, Kodama N, Koiwaya H, Aoyagi S, Imaizumi T.
  • Journal Title: International Journal of Cardiology Volume: 158(2) Issue: 2 Pages: e38-e40
  • DOI: 10.1016/j.ijcard.2011.10.027
  • Peer Reviewed
• [Journal Article] Persistent coronary arterial inflammation in a patient long after the onset of Kawasaki disease (2012)
  • Author(s): Suda K, Tahara N, Kudo Y, Yoshimoto H, Iemura M, Ueno T, Kaida H, Ishibashi M, Imaizumi T.
  • Journal Title: International Journal of Cardiology Volume: 154(2) Issue: 2 Pages: 193-4
  • DOI: 10.1016/j.ijcard.2011.10.078
  • Peer Reviewed
• [Journal Article] Serum levels of advanced glycation end products (AGEs) are independent correlates of insulin resistance in non-diabetic subjects. (2012)
  • Author(s): TaharaN, YamagishiS, TakeuchiM
  • Journal Title: Cardiovasc.Ther. Volume: 30 Issue: 1 Pages: 42-48
  • DOI: 10.1111/j.1755-5922.2010.00177.x
  • Peer Reviewed
• [Journal Article] Impact of ischemia-guided initial diagnosis in patients with stable angina. (2012)
  • Author(s): Tahara N.
  • Journal Title: Circulation Journal Volume: 76(12) Pages: 2742-3
  • NAID: 10031126041
  • Peer Reviewed
• [Journal Article] 特集：心臓核医学の最先端 動脈硬化イメージング－臨床応用 (2012)
  • Author(s): 田原宣広、本多亮博、田原敦子、新田良和、児玉紀洋、溝口ミノリ、今泉 勉
  • Journal Title: PET journal Volume: (18) Pages: 19-21
• [Journal Article] 慢性炎症と疾患 心血管系の慢性炎症 臨床分子イメージングによる心・血管病の診断 (2012)
  • Author(s): 田原宣広、本多亮博、田原敦子、新田良和、児玉紀洋、溝口ミノリ、今泉 勉
  • Journal Title: BIO Clinica Volume: 第1巻第1号 Pages: 90-96
• [Journal Article] Persistent coronary arterial inflammation in a patient long after the onset of Kawasaki disease. (2012)
  • Author(s): Suda K, Tahara N, Kudo Y, Yoshimoto H, Iemura M, Ueno T, Kaida H, Ishibashi M, Imaizumi T.
  • Journal Title: Int J Cardiol Volume: 154(2) Pages: 193-4
  • Peer Reviewed
• [Journal Article] Serum Levels of Advanced Glycation End Products (AGEs) are Independent Correlates of Insulin Resistance in Nondiabetic Subjects. (2012)
  • Author(s): Tahara N, Yamagishi S, Matsui T, Takeuchi M, Nitta Y, Kodama N, Mizoguchi M, Imaizumi T.
  • Journal Title: Cardiovasc Ther Volume: 30(1) Pages: 42-8
  • Peer Reviewed
• [Journal Article] Pioglitazone attenuates atherosclerotic plaque inflammation in patients with impaired glucose tolerance or diabetes a prospective, randomized, comparator-controlled study using serial FDG PET/CT imaging study of carotid artery and ascending aorta (2011)
  • Author(s): Mizoguchi M, Tahara N, Tahara A, Nitta Y, Kodama N, Oba T, Mawatari K, Yasukawa H, Kaida H, Ishibashi M, Hayabuchi N, Harada H, Ikeda H, Yamagishi S, Imaizumi T
  • Journal Title: JACC Cardiovasc Imaging Volume: 4(10) Issue: 10 Pages: 1110-1118
  • DOI: 10.1016/j.jcmg.2011.08.007
  • Peer Reviewed
• [Journal Article] Serum level of pigment epithelium-derived factor is a marker of atherosclerosis in humans (2011)
  • Author(s): Tahara N, Yamagishi S, Tahara A, Nitta Y, Kodama N, Mizoguchi M, Mohar D, Ishibashi M, Hayabuchi N, Imaizumi T
  • Journal Title: Atherosclerosis Volume: 219(1) Issue: 1 Pages: 311-315
  • DOI: 10.1016/j.atherosclerosis.2011.06.022
  • Peer Reviewed
• [Journal Article] Pioglitazone attenuates atherosclerotic plaque inflammation in patients with impaired glucose tolerance or diabetes a prospective, randomized, comparator-controlled study using serial FDG PET/CT imaging study of carotid artery and ascending aorta. (2011)
  • Author(s): Mizoguchi M, Tahara N, Tahara A, Nitta Y, Kodama N, Oba T, Mawatari K, Yasukawa H, Kaida H, Ishibashi M, Hayabuchi N, Harada H, Ikeda H, Yamagishi S, Imaizumi T.
  • Journal Title: JACC Cardiovasc Imaging Volume: 4(10) Pages: 1110-8
  • Peer Reviewed
• [Journal Article] Serum level of pigment epithelium-derived factor is a marker of atherosclerosis in humans. (2011)
  • Author(s): Tahara N, Yamagishi S, Tahara A, Nitta Y, Kodama N, Mizoguchi M, Mohar D, Ishibashi M, Hayabuchi N, Imaizumi T.
  • Journal Title: Atherosclerosis Volume: 219(1) Pages: 311-5
  • Peer Reviewed
• [Presentation] Pulmonary arterial FDG uptake and the disease activity in pulmonary arterial hypertension (2014)
  • Author(s): Honda A, Tahara N, Tahara A, Nitta Y, Kodama N, Ishibashi M, Fukumoto Y
  • Organizer: 第78回日本循環器学会学術集会
  • Place of Presentation: 東京
• [Presentation] Visceral fat metabolic activity is independently associated with coronary artery inflammation in patients with impaired glucose intolerance or type 2 diabetes (2014)
  • Author(s): Honda A, Tahara N, Tahara A, Nitta Y, Kodama N, Mizoguchi M, Ishibashi M, Yamagishi S, Fukumoto Y
  • Organizer: 第78回日本循環器学会学術集会
  • Place of Presentation: 東京
• [Presentation] Effects of pioglitazone on visceral fat metabolic activity in impaired glucose tolerance or type 2 diabetes mellitus (2014)
  • Author(s): Kodama N,Tahara N, Tahara A, Honda A, Nitta Y, Mizoguchi M, Ishibashi M, Ikeda H, Narula J, Yamagishi S, Imaizumi T
  • Organizer: 第78回日本循環器学会学術集会
  • Place of Presentation: 東京
• [Presentation] Molecular Imaging of Vascular Inflammation in Patients with Coronary Artery Disease (2014)
  • Author(s): Tahara N
  • Organizer: The 10th Korean Society of Interventional Cardiology Symposium
  • Place of Presentation: Gyeongju, Korea
• [Presentation] Molecular Imaging of Vascular Inflammation (2014)
  • Author(s): Nobuhiro Tahara
  • Organizer: The 10th Korean Society of Interventional Cardiology
  • Place of Presentation: Gyeongju, South Korea
  • Invited
• [Presentation] Pulmonary arterial FDG uptake and the disease activity in pulmonary arterial hypertension (2014)
  • Author(s): Akihiro Honda, Nobuhiro Tahara, Atsuko Tahara, Yoshikazu Nitta, Norihiro Kodama, Masatoshi Ishibashi, Yoshihiro Fukumoto
  • Organizer: 第78回日本循環器学会学術集会
  • Place of Presentation: 東京都千代田区
• [Presentation] Visceral fat metabolic activity is independently associated with coronary artery inflammation in patients with impaired glucose tolerance or type 2 diabetes (2014)
  • Author(s): Akihiro Honda, Nobuhiro Tahara, Atuko Tahara, Yoshikazu Nitta, Norihiro Kodama, Minori Mizoguchi, Masatoshi Ishibashi, Sho-ichi Yamagishi, Yoshihiro Fukumoto
  • Organizer: 第78回日本循環器学会学術集会
  • Place of Presentation: 東京都千代田区
• [Presentation] Effects of Pioglitazone on Visceral Fat Metabolic Activity in Impaired Glucose Tolerance or Type 2 Diabetes Mellitus (2014)
  • Author(s): Norihiro Kodama, Nobuhiro Tahara, Atsuko Tahara, Akihiro Honda, Yoshikazu Nitta, Minori Mizoguchi, Masatoshi Ishibashi, Hisao Ikeda, Sho-ichi Yamagishi, Yoshihiro Fukumoto
  • Organizer: 第78回日本循環器学会学術集会
  • Place of Presentation: 東京都千代田区
• [Presentation] FDG-PET/CT angiographyを用いた動脈硬化病変における炎症活動性の評価-冠動脈への応用の可能性- (2013)
  • Author(s): 田原宣広
  • Organizer: 第27回日本心臓血管内視鏡学会
  • Place of Presentation: 福岡
  • Year and Date: 2013-10-05
• [Presentation] 動脈硬化の核医学画像診断と臨床応用 (2013)
  • Author(s): 石橋正敏、田原宣広
  • Organizer: 第53回日本核医学会学術総会
  • Place of Presentation: 福岡
• [Presentation] FDG-PET/CTを用いた動脈硬化における分子病態の評価-冠動脈への応用の可能性- (2013)
  • Author(s): 田原宣広
  • Organizer: 第21回日本血管生物医学会学術集会
  • Place of Presentation: 大阪
• [Presentation] 症例徹底討論2座長 (2013)
  • Author(s): 田原宣広、福本義弘
  • Organizer: 第2回日本肺循環学会
  • Place of Presentation: 東京
• [Presentation] FDG-PET imaging may provide a novel biomarker in pulmonary hypertension (2013)
  • Author(s): Tahara N
  • Organizer: Actelion 8th Scientific Symposium
  • Place of Presentation: Tokyo
• [Presentation] Vascular Inflammation Evaluated by FDG-PET is Associated with Endothelial Function (2013)
  • Author(s): Honda A, Tahara N, Tahara A, Nitta Y, Kodama N, Ishibashi M, Imaizumi T
  • Organizer: 第77回日本循環器学会学術集会
  • Place of Presentation: 神奈川
• [Presentation] FDG-PET/CT を用いた動脈硬化における分子病態の評価 －冠動脈への応用の可能性－ (2013)
  • Author(s): 田原宣広
  • Organizer: 第21回日本血管生物医学会学術集会
  • Place of Presentation: 大阪府吹田市
  • Invited
• [Presentation] FDG-PET/CT angiographyを用いた動脈硬化病変における炎症活動性の評価 －冠動脈への応用の可能性－ (2013)
  • Author(s): 田原宣広
  • Organizer: 第27回日本心臓血管内視鏡学会
  • Place of Presentation: 福岡県久留米市
  • Invited
• [Presentation] 血管分子イメージング FDG-PET (2013)
  • Author(s): 田原宣広
  • Organizer: 第13回循環器MDCT研究会
  • Place of Presentation: 東京都品川区
  • Invited
• [Presentation] Effects of Pioglitazone Versus Glimepiride on Abdominal Fat Glucose Metabolism in Patients with Impaired Glucose Tolerance or Type 2 Diabetes Mellitus (2012)
  • Author(s): Kodama N, Tahara N, Honda A, Tahara A, Nitta Y, Mizoguchi M, Ishibashi M, Imaizumi T
  • Organizer: The American Heart Association, The 85th Scientific Sessions
  • Place of Presentation: Los Angeles, USA
• [Presentation] Effects of Pioglitazone on Coronary Arterial Inflammation Evaluated by Serial FDG-PET/CT in Patients with Impaired Glucose Tolerance or Type 2 Diabetes (2012)
  • Author(s): Nitta Y, Tahara N, Honda A, Tahara A, Kodama N, Mizoguchi M, Ishibashi M, Imaizumi T
  • Organizer: The American Heart Association, The 85th Scientific Sessions
  • Place of Presentation: Los Angeles, USA
• [Presentation] FDG-PETを用いた動脈硬化活動性の可視化 (2012)
  • Author(s): 田原宣広、本多亮博、田原敦子、新田良和、児玉紀洋、溝口ミノリ、今泉勉
  • Organizer: 第35回日本高血圧学会総会
  • Place of Presentation: 名古屋
• [Presentation] Successful shunt closure and improvement of hemodynamics following a long-term use of bosentan in congenital heart defect patients with severe pulmonary arterial hypertension and small shunt (2012)
  • Author(s): Tahara N, Imaizumi T
  • Organizer: Actelion 9th Scientific Symposium
  • Place of Presentation: Tokyo
• [Presentation] Effects of Pioglitazone on Coronary Arterial Inflammation in Type 2 Diabetic Patients Evaluated by Serial FDG-PET/CT (2012)
  • Author(s): Nitta Y, Tahara N, Tahara A, Kodama N, Mizoguchi M, Ishibashi M, Imaizumi T
  • Organizer: 第76回日本循環器学会学術集会
  • Place of Presentation: 福岡
• [Presentation] 循環器疾患におけるFDG-PET (2012)
  • Author(s): Tahara N, Honda A, Tahara A, Nitta Y, Kodama N, Mizoguchi M, Imaizumi T
  • Organizer: 第76回日本循環器学会学術集会
  • Place of Presentation: 福岡(モーニングレクチャー)
• [Presentation] Effects of Pioglitazone Versus Glimepiride on Abdominal Fat Glucose Metabolism in Patients with Impaired Glucose Tolerance or Type 2 Diabetes Mellitus. (2012)
  • Author(s): Kodama N, Tahara N, Honda A, Tahara A, Nitta Y, Mizoguchi M, Ishibashi M, Imaizumi T
  • Organizer: The American Heart Association, The 85th Scientific Sessions
  • Place of Presentation: Los Angels, USA
• [Presentation] Effects of Pioglitazone on Coronary Arterial Inflammation Evaluated by Serial FDG-PET/CT in Patients with Impaired Glucose Tolerance or Type 2 Diabetes. (2012)
  • Author(s): Nitta Y, Tahara N, Honda A, Tahara A, Kodama N, Mizoguchi M, Ishibashi M, Imaizumi T.
  • Organizer: The American Heart Association, The 85th Scientific Sessions
  • Place of Presentation: Los Angels, USA
• [Presentation] Successful shunt closure and improvement of hemodynamics following a long-term use of bosentan in congenital heart defect patients with severe pulmonary arterial hypertension and small shunt. (2012)
  • Author(s): Tahara N, Imaizumi T.
  • Organizer: 9th Scientific Symposium
  • Place of Presentation: 東京
• [Presentation] Effects of Pioglitazone on Coronary Arterial Inflammation in Patients with Impaired Glucose Tolerance and Type 2 Diabetes Evaluated by Serial FDG-PET/CT. (2012)
  • Author(s): Nitta Y, Tahara N, Honda A, Tahara A, Kodama N, Mizoguchi M, Ishibashi M, Imaizumi T.
  • Organizer: 第76回日本循環器学会総会
  • Place of Presentation: 福岡
• [Presentation] モーニングレクチャー 循環器疾患におけるFDG-PET (2012)
  • Author(s): Tahara N, Honda A, Tahara A, Nitta Y, Kodama N, Mizoguchi M, Imaizumi T.
  • Organizer: 第76回日本循環器学会総会
  • Place of Presentation: 福岡
  • Invited
• [Presentation] 高血圧 Up-to-Date 2 潜在性臓器障害を検出可能とする新しいモダリティー FDG-PETを用いた動脈硬化活動性の可視化 (2012)
  • Author(s): Tahara N, Honda A, Tahara A, Nitta Y, Kodama N, Mizoguchi M, Imaizumi T.
  • Organizer: 第35回日本高血圧学会総会
  • Place of Presentation: 名古屋
  • Invited
• [Presentation] 炎症と動脈硬化-FDG-PETを用いた動脈硬化活動性の可視化- (2011)
  • Author(s): 田原宣広、本多亮博、田原敦子、新田良和、児玉紀洋、溝口ミノリ、甲斐田勇人、石橋正敏、今泉勉
  • Organizer: 日本心臓病学会・日本心臓核医学会ジョイントシンポジウム
  • Place of Presentation: 神戸
  • Year and Date: 2011-09-24
• [Presentation] ピオグリタゾンがプラーク炎症や内臓脂肪に及ぼす影響 (2011)
  • Author(s): 田原宣広、田原敦子、新田良和、児玉紀洋、溝口ミノリ、今泉勉
  • Organizer: 第10回日本循環器学会九州地方会
  • Place of Presentation: 福岡(ランチョンセミナー)
  • Year and Date: 2011-06-25
• [Presentation] Serum Levels of Advanced Glycation End Products are Independent Correlates of Vascular Inflammation Evaluated by FDG-PET in Humans (2011)
  • Author(s): Tahara A, Tahara N, Honda A, Kodama N, Nitta Y, Mizoguchi M, Ishibashi M, Matsui T, Yamagishi S, Imaizumi T
  • Organizer: The American Heart Association, The 84th Scientific Sessions
  • Place of Presentation: Orland, USA
• [Presentation] Serum Levels of Advanced Glycation End Products are Independent Correlates of Vascular Inflammation Evaluated by FDG-PET in Humans (2011)
  • Author(s): Kodama N, Tahara N, Tahara A, Nitta Y, Mizoguchi M, Ishibashi M, Yamagishi S, Imaizumi T
  • Organizer: 第75回日本循環器学会総会
  • Place of Presentation: 神奈川
• [Presentation] 炎症と動脈硬化-FDG-PETを用いた動脈硬化活動性の可視化- (2011)
  • Author(s): 田原宣広、田原敦子、新田良和、児玉紀洋、溝口ミノリ、甲斐田勇人、石橋正敏、今泉勉
  • Organizer: 第21回日本心臓核医学会総会・学術大会
  • Place of Presentation: 福岡(心臓核医学会賞受賞講演)
• [Presentation] 炎症と動脈硬化-FDG-PETを用いた動脈硬化活動性の可視化- (2011)
  • Author(s): 田原宣広、田原敦子、新田良和、児玉紀洋、溝口ミノリ、甲斐田勇人、石橋正敏、今泉勉
  • Organizer: 第10回日本頚部脳血管治療学会
  • Place of Presentation: 大阪
• [Presentation] Serum Levels of Advanced Glycation End Products are Independent Correlates of Vascular Inflammation Evaluated by FDG-PET in Humans. (2011)
  • Author(s): Tahara A, Tahara N, Honda A, Kodama N, Nitta Y, Mizoguchi M, Ishibashi M, Matsui T, Yamagishi S, Imaizumi T:
  • Organizer: The American Heart Association, The 84th Scientific Sessions
  • Place of Presentation: Orland, USA
• [Presentation] PAHの診断のKey Pointと日常診療の自験例 (2011)
  • Author(s): 田原 宣広、田原敦子、新田 良和、児玉 紀洋、溝口 ミノリ、今泉 勉
  • Organizer: 第1回 南大阪肺高血圧症フォーラム
  • Place of Presentation: 大阪
• [Presentation] 教育講演 動脈硬化プラーク･イメージング 炎症と動脈硬化 -FDG-PETを用いた動脈硬化活動性の可視化- (2011)
  • Author(s): 田原 宣広、田原敦子、新田 良和、児玉 紀洋、溝口 ミノリ、甲斐田勇人、石橋正敏、今泉 勉
  • Organizer: 第10回日本頚部脳血管治療学会
  • Place of Presentation: 大阪
• [Presentation] 心臓核医学会賞受賞講演 炎症と動脈硬化 -FDG-PETを用いた動脈硬化活動性の可視化- (2011)
  • Author(s): 田原 宣広、田原敦子、新田 良和、児玉 紀洋、溝口 ミノリ、甲斐田勇人、石橋正敏、今泉 勉
  • Organizer: 第21回日本心臓核医学会総会・学術大会
  • Place of Presentation: 福岡
• [Presentation] ピオグリタゾンがプラーク炎症や内臓脂肪に及ぼす影響 (2011)
  • Author(s): 田原 宣広、田原敦子、新田 良和、児玉 紀洋、溝口 ミノリ、今泉 勉
  • Organizer: 第10回日本循環器学会九州地方会 ランチョンセミナー
  • Place of Presentation: 福岡
• [Presentation] 膠原病性肺高血圧症に対する早期治療の重要性 (2011)
  • Author(s): 津留智子、大場豊治、田原宣広、田原敦子、児玉紀洋、新田良和、本多亮博、溝口ミノリ、今泉 勉
  • Organizer: Fukuoka PAH conference
  • Place of Presentation: 福岡
• [Presentation] 動脈硬化の分子イメージング 炎症と動脈硬化 -FDG-PETを用いた動脈硬化活動性の可視化 (2011)
  • Author(s): 田原 宣広、本多亮博、田原敦子、新田 良和、児玉 紀洋、溝口 ミノリ、甲斐田勇人、石橋正敏、今泉 勉
  • Organizer: 第24回21世紀カンファレンス
  • Place of Presentation: 福岡
• [Presentation] ジョイントシンポジウム：不安定プラークの病態と画像診断 炎症と動脈硬化 -FDG-PETを用いた動脈硬化活動性の可視化- (2011)
  • Author(s): 田原 宣広、本多亮博、田原敦子、新田 良和、児玉 紀洋、溝口 ミノリ、甲斐田勇人、石橋正敏、今泉 勉
  • Organizer: 日本心臓病学会・日本心臓核医学会
  • Place of Presentation: 神戸
• [Presentation] FDG-PETを用いた心・血管病の分子イメージング (2011)
  • Author(s): 田原 宣広、本多亮博、田原敦子、新田 良和、児玉 紀洋、溝口 ミノリ、甲斐田勇人、石橋正敏、今泉 勉
  • Organizer: 第43回 名古屋心臓核医学研究会
  • Place of Presentation: 名古屋
• [Presentation] Serum Levels of Advanced Glycation End Products are Independent Correlates of Vascular Inflammation Evaluated by FDG-PET in Humans (2011)
  • Author(s): Kodama N, Tahara N, Tahara A, Nitta Y, Mizoguchi M, Ishibashi M, Yamagishi S, Imaizumi T
  • Organizer: 第75回日本循環器学会総会
  • Place of Presentation: 横浜
• [Book] 肺動脈性肺高血圧症の治療と看護HEART nursing 27 (2014)
  • Author(s): 田原宣広
• [Book] Clinical feasibility and monitoring of the effects of anti-inflammatory therapy in atherosclerosis (2014)
  • Author(s): Nobuhiro Tahara, Atsuko Tahara, Sho-ichi Yamagishi
  • Publisher: Springer International Publishing AG, Cham
• [Book] 動脈硬化プラークイメージング(エコー, CT, MRI, FDG-PET)日本臨床71増刊号3 (2013)
  • Author(s): 田原宣広、田原敦子、本多亮博、新田良和、児玉紀洋、溝口ミノリ、今泉勉
• [Book] 心筋症:画像による鑑別診断(総論)循環器内科73 (2013)
  • Author(s): 田原宣広、田原敦子、本多亮博、新田良和、児玉紀洋、溝口ミノリ、今泉勉
• [Book] 炎症と動脈硬化: FDG-PETによる病態評価映像情報メディカル45 (2013)
  • Author(s): 田原宣広
• [Book] 頸動脈プラークの分子イメージングと炎症月刊『カレントテラピー』31 (2013)
  • Author(s): 田原宣広、田原敦子、本多亮博、新田良和、児玉紀洋、福本義弘
• [Book] 動脈硬化のFDG-PETイメージング-冠動脈病変への臨床応用PETジャーナル24 (2013)
  • Author(s): 田原宣広、本多亮博、田原敦子、新田良和、児玉紀洋、溝口ミノリ、福本義弘
• [Book] FDG-PET :分子イメージングを用いて動脈硬化の質を評価する月刊「Heart View」11月増刊号17 (2013)
  • Author(s): 田原宣広、田原敦子、本多亮博、新田良和、児玉紀洋、溝口ミノリ、福本義弘
• [Book] 心臓のFDG-PET検査-心筋viabilityと心サルコイドーシスの評価-心臓45 (2013)
  • Author(s): 田原宣広、田原敦子、本多亮博、新田良和、児玉紀洋、福本義弘
• [Book] CTEPHの内科的治療の適応および新規CTEPH治療薬の有効性と安全性「医薬ジャーナル」49 (2013)
  • Author(s): 田原宣広、田原敦子、本多亮博、新田良和、福本義弘
• [Book] 特発性・遺伝性肺動脈性肺高血圧症Medical View Point 34 (2013)
  • Author(s): 田原宣広
• [Book] World Report海外留学体験記CIRCULATION Up-to-Date 2013:4 (2013)
  • Author(s): 田原宣広、田原敦子
• [Book] 動脈硬化イメージング-臨床応用PET journal 18 (2012)
  • Author(s): 田原宣広、本多亮博、田原敦子、新田良和、児玉紀洋、溝口ミノリ、今泉勉
• [Book] 臨床分子イメージングによる心・血管病の診断BIO Clinica慢性炎症と疾患1(1) (2012)
  • Author(s): 田原宣広、本多亮博、田原敦子、新田良和、児玉紀洋、溝口ミノリ、今泉勉
• [Book] 心サルコイドーシスをどのように診断するかHeart View 16(2) (2012)
  • Author(s): 田原宣広、本多亮博、田原敦子、新田良和、児玉紀洋、溝口ミノリ、甲斐久史、今泉勉
• [Book] Heart View (2012)
  • Author(s): 田原宣広、本多亮博、田原敦子、新田良和、児玉紀洋、溝口ミノリ、甲斐久史、今泉 勉
  • Publisher: メジカルビュー社
• [Book] 動脈硬化プラークの分子イメージング日本冠疾患学会雑誌17 (2) (2011)
  • Author(s): 田原宣広、田原敦子、新田良和、児玉紀洋、溝口ミノリ、今泉勉
• [Book] 日本冠疾患学会雑誌 (2011)
  • Author(s): 田原宣広、田原敦子、新田良和、児玉紀洋、溝口ミノリ、今泉 勉
  • Publisher: 日本冠疾患学会