Development of 3-D database handling the hospital-based cohort population in urban areas in Japan

• Project/Area Number: 23591073
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Circulatory organs internal medicine
• Research Institution: The Cardiovascular Institute
• Principal Investigator: YAMASHITA Takeshi 公益財団法人心臓血管研究所, その他部局等, 研究員 (20302721)
• Project Period (FY): 2011 – 2013
• Project Status: Completed (Fiscal Year 2013)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: コホート研究 / 心不全 / 冠動脈疾患 / 不整脈 / データベース

Research Abstract

The present study aimed to construct a three-dimensional database using a hospital-based cohort population. In this database, we utilized items at enrollment as X-axis, added items of newly detected patient characteristics and therapy during the 1st year as Y-axis, and combined these data with patient outcome during the follow-up. In the study period, we performed the following procedures: (1) arrangement and fixing of items on X- and Y-axis, (2) construct a new software that can handle the 3-D database, and (3) entering the data into the database. After bug fixing work, we constructed the new 3-D hospital-based cohort database. With the 2-dimentional database, we have already published many descriptive data on issues regarding cardiovascular diseases in Japan, which results can be compared with those described with the new 3-D database.

Research Products

• [Journal Article] Coronary artery diseases in Japanese patients with nonvalvular atrial fibrillation (2014)
  • Author(s): Senoo K, Suzuki S, Sagara K, Otsuka T, Matsuno S, Uejima T, Oikawa Y, Yajima J, Nagashima K, Kirigaya H, Sawada H, Aizawa T, Lip GY, Yamashita T
  • Journal Title: J Cardiol Volume: 63 Pages: 123-7
• [Journal Article] Rivaroxaban in clinical practice for atrial fibrillation with special reference to prothrombin time (2014)
  • Author(s): Suzuki S, Otsuka T, Sagara K, Kano H, Matsuno S, Kato Y, Takai H, Uejima T, Oikawa Y, Nagashima K, Kirigaya H, Yajima J, Sawada H, Aizawa T, Yamashita T
  • Journal Title: Circ J Volume: 78 Pages: 763-6
  • NAID: 130003391010
• [Journal Article] Progression to the persistent form in asymptomatic paroxysmal atrial fibrillation (2014)
  • Author(s): Senoo K, Suzuki S, Otsuka T, Sagara K, Matsuno S, Kano H, Uejima T, Oikawa Y, Yajima J, Nagashima K, Kirigaya H, Sawada H, Aizawa T, Yamashita T
  • Journal Title: Circ J Volume: 78 Pages: 1121-6
  • NAID: 130003391080
• [Journal Article] Relationship between cardiopulmonary exercise testing parameters and heart failure risk (H2ARDDscore) in atrial fibrillation (2014)
  • Author(s): Suzuki S, Koike A, Sagara K, Otsuka T, Kano H, Matsuno S, Kato Y, Takai H, Uejima T, Oikawa Y, Nagashima K, Kirigaya H, Yajima J, Sawada H, Aizawa T, Yamashita T
  • Journal Title: J Arrhythmia Volume: 30 Pages: 173-9
• [Journal Article] Effects of statin treatment in patients with coronary artery disease and chronic kidney disease. (2014)
  • Author(s): Hidehiro Kaneko, Junji Yajima, Yuji Oikawa, Shingo Tanaka, Daisuke Fukamachi, Shinya Suzuki, Koichi Sagara, Takayuki Otsuka, Shunsuke Matsuno, Ryuichi Funada, Hiroto Kano, Tokuhisa Uejima, Akira Koike, Kazuyuki Nagashima, Hajime Kirigaya, Hitoshi Sawada, Tadanori Aizawa, Takeshi Yamashita
  • Journal Title: Heart Vessels Volume: 29 Issue: 1 Pages: 21-28
  • DOI: 10.1007/s00380-013-0325-2
  • Peer Reviewed
• [Journal Article] Impact of aging on the clinical outcomes of Japanese patients with coronary artery disease after percutaneous coronary intervention. (2014)
  • Author(s): Hidehiro Kaneko, Junji Yajima, Yuji Oikawa, Shingo Tanaka, Daisuke Fukamachi, Shinya Suzuki, Koichi Sagara, Takayuki Otsuka, Syunsuke Matsuno, Ryuichi Funada Hiroto Kano, Tokuhisa Uejima, Akira Koike, Kazuyuki Nagashima, Hajime Kirigaya, Hitoshi Sawada, Tadanori Aizawa, Takeshi Yamashita
  • Journal Title: Heart Vessels Volume: 29 Issue: 2 Pages: 156-164
  • DOI: 10.1007/s00380-013-0339-9
  • Peer Reviewed
• [Journal Article] Coronary artery diseases in Japanese patients with nonvalvular atrial fibrillation (2014)
  • Author(s): Keitaro Senoo, Shinya Suzuki, Koichi Sagara, Takayuki Otsuka, Shunsuke Matsuno, Tokuhisa Uejima, Yuji Oikawa, Junji Yajima, Kazuyuki Nagashima, Hajime Kirigaya, Hitoshi Sawada, Tadanori Aizawa, Gregory Y.H. Lip, and Takeshi Yamashita
  • Journal Title: Journal of Cardiology Volume: 63 Issue: 2 Pages: 123-127
  • DOI: 10.1016/j.jjcc.2013.08.007
  • Peer Reviewed / Open Access
• [Journal Article] Role of arterial stiffness and impaired renal function in the progression of new coronary lesions after percutaneous coronary intervention (2013)
  • Author(s): Kaneko H, Yajima J, Oikawa Y, Matsuno S, Funada R, Tanaka S, Fukamachi D, Suzuki S, Aizawa T, Yamashita T
  • Journal Title: Cardiovasc Interv Ther Volume: 28 Pages: 56-62
• [Journal Article] Effects of statin treatment in patients with coronary artery disease and chronic kidney disease (2013)
  • Author(s): Kaneko H, Yajima J, Oikawa Y, Tanaka S, Fukamachi D, Suzuki S, Sagara K, Otsuka T, Matsuno S, Funada R, Kano H, Uejima T, Koike A, Nagashima K, Kirigaya H, Sawada H, Aizawa T, Yamashita T
  • Journal Title: Heart Vessels
• [Journal Article] Coronary artery diseases in Japanese patients with nonvalvular atrial fibrillation (2013)
  • Author(s): Senoo K, Suzuki S, Sagara K, Otsuka T, Matsuno S, Uejima T, Oikawa Y, Yajima J, Nagashima K, Kirigaya H, Sawada H, Aizawa T, Lip GY, Yamashita T
  • Journal Title: J Cardiol Volume: 13 Pages: 250-5
• [Journal Article] Effects of Smoking Habit on the Prevalence of Atrial Fibrillation in Japanese Patients With Special Reference to Sex Differences (2013)
  • Author(s): Suzuki S, Sagara K, Otsuka T, Kano H, Matsuno S, Takai H, Uejima T, Oikawa Y, Koike A, Nagashima K, Kirigaya H, Yajima J, Tanabe H, Sawada H, Aizawa T, Yamashita T
  • Journal Title: Circ J Volume: (in press)
• [Journal Article] Blue letter effects: Changes in physicians' attitudes towarddabigatran after a safety advisory in a specialized hospital for cardiovascular care in Japan (2013)
  • Author(s): Suzuki S, Sagara K, Otsuka T, Kano H, Matsuno S, Takai H, Uejima T, Oikawa Y, Koike A, Nagashima K, Kirigaya H, Yajima J, Tanabe H, Sawada H, Aizawa T, Yamashita T
  • Journal Title: J Cardiol Volume: 62 Pages: 366-73
• [Journal Article] Usefulness of frequent supraventricular extrasystoles and a high CHADS2 score to predict first-time appearance of atrial fibrillation (2013)
  • Author(s): Suzuki S, Sagara K, Otsuka T, Kano H, Matsuno S, Takai H, Uejima T, Oikawa Y, Koike A, Nagashima K, Kirigaya H, Yajima J, Tanabe H, Sawada H, Aizawa T, Yamashita T
  • Journal Title: Am J Cardiol Volume: 111 Pages: 1602-7
• [Journal Article] Estimated glomerular filtration rate and proteinuria are associated with persistent form of atrial fibrillation : analysis in Japanese patients (2013)
  • Author(s): Suzuki S, Sagara K, Otsuka T, Kanou H, Matsuno S, Uejima T, Oikawa Y, Koike A, Nagashima K, Kirigaya H, Yajima J, Sawada H, Aizawa T, Yamashita T
  • Journal Title: J Cardiol Volume: 61 Pages: 53-7
• [Journal Article] Obesity paradox in Japanese patients after percutaneous coronary intervention : an observation cohort study (2013)
  • Author(s): Kaneko H, Yajima J, Oikawa Y, Tanaka S, Fukamachi D, Suzuki S, Sagara K, Otsuka T, Matsuno S, Funada R, Kano H, Uejima T, Koike A, Nagashima K, Kirigaya H, Sawada H, Aizawa T, Yamashita T
  • Journal Title: J Cardiol Volume: 62 Pages: 18-24
• [Journal Article] Clinical characteristics and long-term clinical outcomes of Japanese heart failure patients with preserved versus reduced left ventricular ejection fraction : a prospective cohort of Shinken Database 2004-2011 (2013)
  • Author(s): Kaneko H, Suzuki S, Yajima J, Oikawa Y, Sagara K, Otsuka T, Matsuno S, Kano H, Uejima T, Koike A, Nagashima K, Kirigaya H, Sawada H, Aizawa T, Yamashita T
  • Journal Title: J Cardiol Volume: 62 Pages: 102-9
• [Journal Article] Recent characteristics and outcomes of Japanese stable angina pectoris after percutaneous coronary intervention. An observational cohort study using the Shinken Database (2013)
  • Author(s): Kaneko H, Yajima J, Oikawa Y, Tanaka S, Fukamachi D, Suzuki S, Sagara K, Otsuka T, Matsuno S, Funada R, Kano H, Uejima T, Koike A, Nagashima K, Kirigaya H, Sawada H, Aizawa T, Yamashita T
  • Journal Title: Int Heart J Volume: 54 Pages: 335-40
• [Journal Article] Clinical characteristics and long-term clinical outcomes of Japanese heart failure patients with preserved versus reduced left ventricular ejection fraction: a prospective cohort of Shinken Database 2004-2011. (2013)
  • Author(s): Hidehiro Kaneko, Shinya Suzuki, Junji Yajima, Yuji Oikawa, Koichi Sagara, Takayuki Otsuka, Shunsuke Matsuno, Hiroto Kano, Tokuhisa Uejima, Akira Koike, Kazuyuki Nagashima, Hajime Kirigaya, Hitoshi Sawada, Tadanori Aizawa, Takeshi Yamashita
  • Journal Title: Journal of Cardiology Volume: 62 Issue: 2 Pages: 102-109
  • DOI: 10.1016/j.jjcc.2013.03.013
  • Peer Reviewed
• [Journal Article] Obesity Paradox in Japanese Patients after Percutaneous Coronary Intervention: an Observation Cohort Study (2013)
  • Author(s): Hidehiro Kaneko, Junji Yajima, Yuji Oikawa, Shingo Tanaka,Daisuke Fukamachi, Shinya Suzuki, Koichi Sagara, Takayuki Otsuka, Shunsuke Matsuno, Ryuichi Funada, Hiroto Kano, Tokuhisa Uejima, Akira Koike, Kazuyuki Nagashima, Hajime Kirigaya, Hitoshi Sawada, Tadanori Aizawa, Takeshi Yamashita
  • Journal Title: Journal of Cardiology Volume: 62 Issue: 1 Pages: 18-24
  • DOI: 10.1016/j.jjcc.2013.02.009
  • Peer Reviewed
• [Journal Article] “Blue letter effects”: Changes in physicians’ attitudes toward dabigatran after a safety advisory in a specialized hospital for cardiovascular care in Japan. (2013)
  • Author(s): Shinya Suzuki, Koichi Sagara, Takayuki Otsuka, Hiroto Kano, Shunsuke Matsuno, Hideaki Takai, Tokuhisa Uejima, Yuji Oikawa, Akira Koike, Kazuyuki Nagashima, Hajime Kirigaya, Junji Yajima, Hiroaki Tanabe, Hitoshi Sawada, Tadanori Aizawa, and Takeshi Yamashita
  • Journal Title: Journal of Cardiology Volume: 62 Issue: 6 Pages: 366-373
  • DOI: 10.1016/j.jjcc.2013.05.016
  • Peer Reviewed
• [Journal Article] Effects of Smoking Habit on the Prevalence of Atrial Fibrillation in Japanese Patients With Special Reference to Sex Differences– Evidence From the Shinken Database – (2013)
  • Author(s): Shinya Suzuki, Koichi Sagara, Takayuki Otsuka, Hiroto Kano, Shunsuke Matsuno, Hideaki Takai, Tokuhisa Uejima, Yuji Oikawa, Akira Koike, Kazuyuki Nagashima, Hajime Kirigaya, Junji Yajima, Hiroaki Tanabe, Hitoshi Sawada, Tadanori Aizawa, Takeshi Yamashita
  • Journal Title: Circulation Journal Volume: 77 Pages: 2948-2953
  • NAID: 10031203580
  • Peer Reviewed
• [Journal Article] Usefulness of Frequent Supraventricular Extrasystoles and a High CHADS2 Score to Predict First-Time Appearance of Atrial Fibrillation. (2013)
  • Author(s): Shinya Suzuki, Koichi Sagara, Takayuki Otsuka, Hiroto Kano, Shunsuke Matsuno, Hideaki Takai, Tokuhisa Uejima, Yuji Oikawa, Akira Koike, Kazuyuki Nagashima, Hajime Kirigaya, Junji Yajima, Hiroaki Tanabe, Hitoshi Sawada, Tadanori Aizawa, Takeshi Yamashita
  • Journal Title: American Journal of Cardiology Volume: 111 Issue: 11 Pages: 1602-1607
  • DOI: 10.1016/j.amjcard.2013.01.335
  • Peer Reviewed
• [Journal Article] Gender-specific relationships between serum uric acid level and prevalence of atrial fibrillation (2012)
  • Author(s): Suzuki S, Otsuka T, Sagara K, Uejima T, Oikawa Y, Yajima J, Koike A, Nagashima K, Kirigaya H, Ogasawara K, Sawada H, Aizawa T, Yamashita T
  • Journal Title: Circ J Volume: 76 Pages: 755-757
• [Journal Article] Dabigatran in Clinical Practice for Atrial Fibrillation With Special Reference to Activated Partial Thromboplastin Time (2012)
  • Author(s): Suzuki S, Otsuka T, Sagara K, Matsuno S, Funada R, Uejima T, Oikawa Y, Yajima J, Koike A, Nagashima K, Kirigaya H, Sawada H, Aizawa T, Yamashita T
  • Journal Title: Circ J Volume: 76 Pages: 755-757
  • NAID: 10030130511
• [Journal Article] Relationship between 24-h Holter recordings and clinical outcomes in patients with permanent atrial fibrillation (2012)
  • Author(s): Hirano K, Yamashita T, Suzuki S, Hayama E, Matsuoka J, Otsuka T, Sagara K, Fu LT, Sawada H, Aizawa T, Nakazato Y, Daida H
  • Journal Title: J Cardiol Volume: 60 Pages: 42-6
  • NAID: 10031187767
• [Journal Article] Distribution of first-detected atrial fibrillation patients without structural heart diseases in symptom classifications (2012)
  • Author(s): Senoo K, Suzuki S, Sagara K, Otsuka T, Matsuno S, Funada R, Uejima T, Oikawa Y, Yajima J, Koike A, Nagashima K, Kirigaya H, Sawada H, Aizawa T, Yamashita T
  • Journal Title: Circ J Volume: 76(4) Pages: 1020-3
  • NAID: 10030131782
• [Journal Article] Role of cardiopulmonary dysfunction and left atrial remodeling in development of acute decompensated heart failure in chronic heart failure with preserved left ventricular ejection fraction (2012)
  • Author(s): Kaneko H, Koike A, Senoo K, Tanaka S, Suzuki S, Nagayama O, Sagara K, Otsuka T, Matsuno S, Funada R, Uejima T, Oikawa Y, Yajima J, Nagashima K, Kirigaya H, Sawada H, Aizawa T, Yamashita T
  • Journal Title: J Cardiol
  • NAID: 10031187757
• [Journal Article] A New Scoring System for Evaluating the Risk of Heart Failure Events in Japanese Patients With Atrial Fibrillation (2012)
  • Author(s): Suzuki S, Sagara K, Otsuka T, Matsuno S, Funada R, Uejima T, Oikawa Y, Yajima J, Koike A, Nagashima K, Kirigaya H, Sawada H, Aizawa T, Yamashita T
  • Journal Title: Am J Cardiol
• [Journal Article] Basic echocardiographic features of patients with latent left ventricular outflow tract obstruction without left ventricular hypertrophy (2012)
  • Author(s): Semba H, Sawada H, Uejima T, Takeda N, Soma K, Abe H, Yamashita T, Nagai R
  • Journal Title: Int Heart J Volume: 53 Pages: 230-3
  • NAID: 130001914152
• [Journal Article] the Shinken Database Study Group. Impact of early statin initiation on secondary prevention in Japanese patients with coronary artery disease (2011)
  • Author(s): Nakamura M, Yamashita T, Yajima J, Oikawa Y, Ogasawara K, Sagara K, Koike A, Kirigaya H, Nagashima K, Otsuka T, Uejima T, Funada R, Matsuno S, Suzuki S, Sawada H, Aizawa T
  • Journal Title: J Cardiol Volume: 57 Pages: 172-180
• [Journal Article] Recent mortality of Japanese patients with atrial fibrillation in an urban city of Tokyo (2011)
  • Author(s): Suzuki S, Yamashita T, Otsuka T, Sagara K, Uejima T, Oikawa Y, Yajima J, Koike A, Nagashima K, Kirigaya H, Ogasawara K, Sawada H, Aizawa T
  • Journal Title: J Cardiol Volume: 58 Pages: 116-23
  • NAID: 10031159582