Project/Area Number |
23591151
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Respiratory organ internal medicine
|
Research Institution | Osaka University |
Principal Investigator |
SEKI Masafumi 大阪大学, 医学部附属病院, 講師 (80432970)
|
Co-Investigator(Kenkyū-buntansha) |
TOMONO Kazunori 大阪大学, 医学部附属病院, 教授 (40202204)
|
Project Period (FY) |
2011 – 2013
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 肺炎 / インフルエンザ / 好中球 / NETs / 次世代シークエンサー / NETs / MRSA / NHCAP / iインフルエンザ / 乳酸菌 |
Research Abstract |
In the basic research field, we analyzed the excessive immune responses, including apoptosis and NETs: neutrophil extracelluar traps, in both human pneuminia cases and mice models. In clinical research field, NHCAP: the nurshing and healthcare-associated pneumonia, cases were analyzed, and published the paper about therapeutic regimen and infection control for aspiration pneumonia in elderly persons and nosocomial pneumonia due to drug resistant pathogens, including MRSA.
|