Artifical kidney established by human kidney derived iPS cells
| Project/Area Number |
23591183
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Kidney internal medicine
|
|---|
| Research Institution | The University of Tokyo |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
FUJITA Toshiro 東京大学, 先端研, 特任教授 (10114125)
NAKAUCHI Hiromitsu 東京大学, 医科学研究所, 教授 (40175485)
ABURATANI Hiroyuki 東京大学, 先端研, 教授 (10202657)
|
|---|
| Project Period (FY) |
2011-04-28 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
|---|
| Keywords | 幹細胞 / iPS cells / メチル化 / 再生医学 / iPS細胞 / 再生医療 / マイクロアレイ |
|---|
| Outline of Final Research Achievements |
In this study, we firstly identified key genes that determine memory of kidney derived iPS cells. By using these genes, we induced kidney cells efficiently from iPS cells. Finally, we tried to establish artificial kidney that was reported by Lanza et al. However, we could not reproduce the device by using human kidney derived iPS cells.
|
Report
(5 results)
Research Products
(14 results)
-
-
[Journal Article] Immunomodulation with eicosapentaenoic acid supports the treatment of autoimmune small-vessel vasculitis.2014
Author(s)
Hirahashi J, Kawahata K, Arita M, Iwamoto R, Hishikawa K, Honda M, Hamasaki Y, Tanaka M, Okubo K, Kurosawa M, Takase O, Nakakuki M, Saiga K, Suzuki K, Kawachi S, Tojo A, Seki G, Marumo T, Hayashi M, Fujita T.
-
Journal Title
Sci. Rep
Volume: 4
Issue: 1
Pages: 6406-6406
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
-
-
[Journal Article] The role of NF-κB signaling in the maintenance of pluripotency of human induced pluripotent stem cells.2013
Author(s)
Takase O, Yoshikawa M, Idei M, Hirahashi J, Fujita T, Takato T, Isagawa T, Nagae G, Suemori H, Aburatani H, Hishikawa K.
-
Journal Title
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
