Analysis of DNA repair, cell cycle progression and cell death in dedifferentiation and regeration of renal tubular cells
| Project/Area Number |
23591194
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Kidney internal medicine
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| Research Institution | Kochi University |
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Principal Investigator |
HIRANO SEIKI 高知大学, 教育研究部医療学系, 助教 (20368616)
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| Co-Investigator(Kenkyū-buntansha) |
TERADA Yoshio 高知大学, 教育研究部医療学系, 教授 (30251531)
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| Project Period (FY) |
2011 – 2013
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| Project Status |
Completed (Fiscal Year 2013)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2012: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 腎尿細管障害 / 急性腎障害 / 細胞周期 / DNA修復 / 尿細管再生 |
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| Research Abstract |
The number of hemodialysis patient is increasing, which is a critical problem in Japan. To analyze repair and regeneration of renal tubular cells after renal failure will contribute the way of preventive therapy of renal disease. I found that renal tubular cells express the markers of de-differentiation after cell damage and they form tubule when the marker is expressed. I am trying to do further analyses.
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Report
(4 results)
Research Products
(2 results)
