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The systemic NAD world in chronic kidney disease

Research Project

Project/Area Number 23591218
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Kidney internal medicine
Research InstitutionThe University of Tokushima

Principal Investigator

TATSUMI Sawako  徳島大学, ヘルスバイオサイエンス研究部, 助教 (80420545)

Co-Investigator(Kenkyū-buntansha) KIDO Shinsuke  徳島大学, 大学院ヘルスバイオサイエンス研究部, 特任助教 (30437652)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2012: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywordsリン / ニコチンアミド / NAD / 慢性腎臓病 / リン代謝
Research Abstract

This study determines the presence of the new phosphate(Pi)metabolic pathway through the nicotinamide phosphoribosyltransferase(Nampt)as the first rate-limiting enzyme in converting NAM to NAD.The activation of Nampt caused the significantly increased levels of urinary Pi excretion and the decreased levels of intestinal Pi absorption.The present data suggest that the cause of hypophosphatemia and hyperphosphaturia observed after 70% hepatectomy is caused by abnormal Nampt/NAM activation in the liver and kidney.
These result shows presence of the liver-kidney axsis in Pi metabolism.
We examine a mechanism to do constantly the Pi/Ca ratio through Nampt.We think these research may be contribute to the prevention of cardiovascular disease development of patients with chronic renal disease.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (82 results)

All 2014 2013 2012 2011

All Journal Article (15 results) (of which Peer Reviewed: 13 results,  Open Access: 2 results) Presentation (53 results) (of which Invited: 4 results) Book (14 results)

  • [Journal Article] Molecular Mechanisms of Cadmium-Induced Fibroblast growth Factor 23 Upregulation in Osteoblast-Like Cells2014

    • Author(s)
      Kido S, Fujihara M, Nomura K, Sasaki S(他8名)
    • Journal Title

      Toxicol Sci. Jun

      Volume: 139(2) Issue: 2 Pages: 301-316

    • DOI

      10.1093/toxsci/kfu043

    • Related Report
      2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Hepatectomy-Related Hypophosphatemia : A Novel Phosphaturic Factor in the Liver-Kidney Axis2014

    • Author(s)
      Nomura K, Tatsumi S, Miyamoto K(他10名)
    • Journal Title

      J Am Soc Nephrol

      Volume: vol.25, No.4 Issue: 4 Pages: 761-772

    • DOI

      10.1681/asn.2013060569

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Sodium-dependent inorganic phosphate transporters and biomineralization2014

    • Author(s)
      Tatsumi S, Fujii O, Miyagawa A, Miyamoto K
    • Journal Title

      Clin Calcium

      Volume: 24(2) Pages: 249-255

    • Related Report
      2013 Final Research Report
  • [Journal Article] Effect of dietary components on renal inorganic phosphate (Pi) excretion induced by a Pi-depleted diet2014

    • Author(s)
      Ohnishi R, Segawa H, Ohmoto T, Sasaki S, Hanazaki A, Mori A, Ikuta K, Furutani J, Kawakami E, Tatsumi S, Hamada Y, Miyamoto K
    • Journal Title

      J Med Invest

      Volume: 61(1.2) Pages: 162-170

    • NAID

      130004822704

    • URL

      https://www.jstage.jst.go.jp/browse/jmi/61/0/_contents

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sodium-dependent inorganic phosphate transporters and biomineralization.2014

    • Author(s)
      Tatsumi S, Fujii O, Miyagawa A, Miyamoto K.
    • Journal Title

      Clin Calcium.

      Volume: Feb;24(2) Pages: 249-255

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of dietary components on renal inorganic phosphate (Pi) excretion induced by a Pi-depleted diet.2014

    • Author(s)
      Ohnishi R, Segawa H, Ohmoto T, Sasaki S, Hanazaki A, Mori A, Ikuta K, Furutani J, Kawakami E, Tatsumi S, Hamada Y, Miyamoto K.
    • Journal Title

      J Med Invest.

      Volume: 61(1.2) Pages: 162-170

    • NAID

      130004822704

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular Mechanisms of Cadmium-Induced Fibroblast growth Factor 23 Upregulation in Osteoblast-Like Cells.2014

    • Author(s)
      Kido S, Fujihara M, Nomura K, Sasaki S, Mukai R, Ohnishi R, Kaneko I, Segawa H, Tatsumi S, Izumi H, Kohno K, Miyamoto KI.
    • Journal Title

      Toxicol Sci.

      Volume: Apr 19

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Vitamin D and type II sodium-dependent phosphate cotransporters. Contrib Nephrol2013

    • Author(s)
      Kido S, Kaneko I, Tatsumi S, Segawa H, Miyamoto K
    • Journal Title

      Contrib Nephrol

      Volume: 180 Pages: 86-97

    • DOI

      10.1159/000346786

    • ISBN
      9783318023695, 9783318023701
    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fibroblast growth factor 23 mediates the phosphaturic actions of cadomium2012

    • Author(s)
      Kido S, Fujihara M, Nomura K, Sasaki S, Shiozaki Y, Segawa H, Tatsumi S, Miyamoto K
    • Journal Title

      Nihon Eiseigaku Zasshi

      Volume: 67(4) Pages: 464-471

    • URL

      https://www.jstage.jst.go.jp/browse/jjh/67/4/_contents

    • Related Report
      2013 Final Research Report 2012 Research-status Report
  • [Journal Article] Identification and functional analysis of a splice variant of mouse sodium-dependent phosphate transporter Npt2c2012

    • Author(s)
      Kuwahara S, Aranami F, Segawa H, Onitsuka A, Honda N, Tominaga R, Hanabusa E, Kaneko I, Yamanaka S, Sassaki S, Ohi A, Nomura K, Tatsumi S, Kido S, Ito M, Miyamoto K
    • Journal Title

      J Med Invest

      Volume: 59(1.2) Pages: 116-126

    • NAID

      130004465255

    • URL

      https://www.jstage.jst.go.jp/browse/jmi/59/1,2/_contents

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Processing and stability of type II sodium-dependent phosphate cotransporter mutations in patients with hereditary hypophosphatemic rickets with hypercalciuria2012

    • Author(s)
      Haito-Sugino S, et al
    • Journal Title

      Am J Physiol Cell Physiol

      Volume: (In press) Issue: 9 Pages: C1316-C1330

    • DOI

      10.1152/ajpcell.00314.2011

    • Related Report
      2013 Final Research Report 2012 Research-status Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Identification and functional analysis of a splice variant of mouse sodium-dependent phosphate transporter Npt2c2012

    • Author(s)
      Kuwahara S
    • Journal Title

      J Med Invest

      Volume: 59 Pages: 116-126

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Identification and functional analysis of a splice variant of mouse sodium-dependent phosphate transporter Npt2c2012

    • Author(s)
      Kuwahara S, et al
    • Journal Title

      The Journal of Medical Investigation

      Volume: 59 Issue: 1,2 Pages: 116-126

    • DOI

      10.2152/jmi.59.116

    • NAID

      130004465255

    • ISSN
      1343-1420, 1349-6867
    • Related Report
      2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Sodium-dependent phosphate cotransporters : Lessons from gene knock out mutation studies2011

    • Author(s)
      Miyamoto K, et al
    • Journal Title

      J Pharm Sci

      Volume: 100 Issue: 9 Pages: 3719-3730

    • DOI

      10.1002/jps.22614

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Journal Article] Inorganic phosphate homeostasis in sodium-dependent phosphate co-transporter Npt2b+/- mice2011

    • Author(s)
      Ohi A, et al
    • Journal Title

      Am J Physiol Renal Physiol

      Volume: 1 Issue: 5 Pages: F1105-F1113

    • DOI

      10.1152/ajprenal.00663.2010

    • Related Report
      2013 Final Research Report 2011 Research-status Report
    • Peer Reviewed
  • [Presentation] リン恒常性維持機構の破綻と疾患-腎臓切除によるリン恒常性破綻機構の解明2014

    • Author(s)
      辰巳佐和子
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学(熊本県)
    • Year and Date
      2014-03-30
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] 骨細胞死滅マウスにおけるカルシウム/リン代謝異常機構について.2014

    • Author(s)
      辰巳佐和子,藤田みゆき,藤井理,野村憲吾,木戸慎介,瀬川博子,宮本賢一.
    • Organizer
      第17回日本病態栄養学会年次学術集会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Related Report
      2013 Annual Research Report
  • [Presentation] リン恒常性維持機構の破綻と疾患-腎臓切除によるリン恒常性破綻機構の解明.2014

    • Author(s)
      辰巳佐和子.
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      .熊本大学(熊本県)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Hepatectomy Hypophosphatemia : A Novel Phosphaturic Factor in the Liver Kidney Axis2013

    • Author(s)
      Nomura K, Tatsumi S, Miyagawa A, Shiozaki Y, Sasaki S, Segawa H, Miyamoto K
    • Organizer
      American Society of Nephrology
    • Place of Presentation
      GeorgiaWorldCongressCenter, Atlanta,GA,USA
    • Year and Date
      2013-11-08
    • Related Report
      2013 Final Research Report
  • [Presentation] 骨とリン利尿因子2013

    • Author(s)
      辰巳佐和子,木戸慎介,瀬川博子,宮本賢一
    • Organizer
      第58回日本透析医学会学術集会・総会
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Year and Date
      2013-06-21
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Hepatectomy Hypophosphatemia:A Novel Phosphaturic Factor in the Liver Kidney Axis.2013

    • Author(s)
      Nomura K, Tatsumi S, Miyagawa A, Shiozaki Y, Sasaki S, Segawa H, Miyamoto K.
    • Organizer
      American Society of Nephrology(第46会米国腎臓学会)
    • Place of Presentation
      ジョージア・ワールド・コングレス・センター(USA)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 骨細胞死滅マウスにおけるリン利尿促進機序について.2013

    • Author(s)
      辰巳佐和子,釜谷達哉,宮本賢一.
    • Organizer
      第56回日本腎臓学会学術総会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Related Report
      2013 Annual Research Report
  • [Presentation] リン利尿におけるKlothoの役割.2013

    • Author(s)
      佐々木祥平,瀬川博子,大西沙織,森絢香,向井朋,真鍋舞,日下祐里,木戸慎介,辰巳佐和子 宮本賢一.
    • Organizer
      第56回日本腎臓学会学術総会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 肝臓切除患者における低リン血症発症機構の解明.2013

    • Author(s)
      野村憲吾,辰巳佐和子,宮川淳美,岡奈都紀,塩崎雄治,木戸慎介,瀬川博子,佐野光枝,福渡努, 柴田克己,宮本賢一.
    • Organizer
      第67回日本栄養・食糧学会大会
    • Place of Presentation
      名古屋大学東山キャンパス(愛知県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Nampt+/-のリン代謝の解析.2013

    • Author(s)
      宮川淳美,辰巳佐和子,野村憲吾,木戸慎介,瀬川博子,宮本賢一.
    • Organizer
      第67回日本栄養・食糧学会大会
    • Place of Presentation
      名古屋大学東山キャンパス(愛知県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 慢性腎臓病に併存する骨ミネラル代謝障害(CKD-MBD)の発症並びに進展におけるFGF23の関与2013

    • Author(s)
      木戸慎介,越智美佐子,藤原真理奈,向井朋,塩崎雄治,瀬川博子,辰巳佐和子,宮本賢一.
    • Organizer
      第67回日本栄養・食糧学会大会
    • Place of Presentation
      名古屋大学東山キャンパス(愛知県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 骨とリン利尿因子.2013

    • Author(s)
      辰巳佐和子,木戸慎介,瀬川博子,宮本賢一.
    • Organizer
      第58回日本透析医学会学術集会・総会
    • Place of Presentation
      福岡国際会議場(福岡県)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 腎臓と骨を結ぶリン代謝調節機序の解明.2013

    • Author(s)
      野村憲吾.
    • Organizer
      第7回瀬戸内フォーラム
    • Place of Presentation
      ホテル北野プラザ六甲荘(兵庫県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 肝臓切除患者における低リン血症発症機序の解明.2013

    • Author(s)
      辰巳佐和子,野村憲吾,大西律子,宮本賢一.
    • Organizer
      第60回日本栄養改善学会学術総会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 近位尿細管上皮細胞におけるNa+依存性無機リン酸輸送担体Npt2cの発現調節とVacuole形成.2013

    • Author(s)
      塩崎雄治,瀬川博子,大西沙織,大井彰子,杉野紗貴子,簑島さくら,伊藤美紀子,木戸慎介,辰巳佐和子,宮本賢一.
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 肝臓切除による無機リン酸恒常性破綻機構について.2013

    • Author(s)
      野村憲吾,辰巳佐和子,宮川淳美,塩崎雄治,瀬川博子,宮本賢一.
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 肝臓切除に起因する低リン血漿発症機構の解明2013

    • Author(s)
      野村憲吾
    • Organizer
      第16回日本病態栄養学会年次学術集会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Related Report
      2012 Research-status Report
  • [Presentation] 腸管リン吸収における腸アルカリフォスファターゼの役割2013

    • Author(s)
      日下祐里
    • Organizer
      第16回日本病態栄養学会年次学術集会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Related Report
      2012 Research-status Report
  • [Presentation] 慢性腎臓病におけるFGF23産生亢進の分子機能解析2013

    • Author(s)
      木戸慎介
    • Organizer
      第16回日本病態栄養学会年次学術集会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Related Report
      2012 Research-status Report
  • [Presentation] Molecular mechanisms of cadmium (Cd) dependent fibroblast growth factor 23 secretion in bone2012

    • Author(s)
      Kido S, Fujiwara M, Nomura K, Sasaki S, Shiozaki Y, Segawa H, Tatsumi S, Miyamoto K
    • Organizer
      Americal Society of Nephrology
    • Place of Presentation
      San Diego Convention Center, CA,USA(oral presentation)
    • Year and Date
      2012-11-02
    • Related Report
      2013 Final Research Report
  • [Presentation] Mechanisms of hyperphosphatemia in the osteocyte-abelated mice2012

    • Author(s)
      Tatsumi S, Kamatani T, Nomura K, Yoshimi A, Shiozaki Y, Sasaki S, Manabe M, Kido S, Segawa H, Miyamoto K
    • Organizer
      Americal Society of Nephrology
    • Place of Presentation
      San Diego Convention Center, CA,USA
    • Year and Date
      2012-11-02
    • Related Report
      2013 Final Research Report
  • [Presentation] Clinical consequences of gene mutations involved in renal phosphate transport2012

    • Author(s)
      Miyamoto K, Ohnishi S, Shiozaki Y, Segawa H, Tatsumi S
    • Organizer
      International Symposium on Epithelial Barrier and Transport
    • Place of Presentation
      Ritsumeikan University. Kusatsu, Shiga, Japan
    • Year and Date
      2012-09-16
    • Related Report
      2013 Final Research Report
  • [Presentation] Muscle atrophy in patients with CKD results from FGF23/Klotho-mediated suppression of Insulin/IGF-I signaling2012

    • Author(s)
      Kido S, Hashimoto Y, Segawa H, Tatsumi S, Miyamoto K
    • Organizer
      XVI International Congress on Nutrition and Metabolism in Renal Disease
    • Place of Presentation
      Hilton Hawaian Village, Honolulu, Hawaii, USA
    • Year and Date
      2012-06-27
    • Related Report
      2013 Final Research Report
  • [Presentation] Muscle atrophy in patients with CKD results from FGF23/Klotho-mediated suppression of Insulin/IGF-I signaling2012

    • Author(s)
      Kido S
    • Organizer
      XVI International Congress on Nutrition and Metabolism in Renal Disease 2012
    • Place of Presentation
      ヒルトン・ハワイアンビレッジ(USA)
    • Related Report
      2012 Research-status Report
  • [Presentation] The role of salivary glands in phosphate homeostasis2012

    • Author(s)
      Mukai T
    • Organizer
      XVI International Congress on Nutrition and Metabolism in Renal Disease 2012
    • Place of Presentation
      ヒルトン・ハワイアンビレッジ(USA)
    • Related Report
      2012 Research-status Report
  • [Presentation] Molecular mechanisms of cadmium (Cd) dependent fibroblast growth factor 23 secretion in bone2012

    • Author(s)
      Kido S
    • Organizer
      Americal Society Nephrology
    • Place of Presentation
      サンディエゴ・コンベンションセンター(USA)
    • Related Report
      2012 Research-status Report
  • [Presentation] Mechanisms of hyperphosphatemia in the osteocyte-abelated mice2012

    • Author(s)
      Tatsumi S
    • Organizer
      Americal Society Nephrology
    • Place of Presentation
      サンディエゴ・コンベンションセンター(USA)
    • Related Report
      2012 Research-status Report
  • [Presentation] Clinical consequences of gene mutations involved in renal phosphate transport2012

    • Author(s)
      Miyamoto K
    • Organizer
      International Symposium on Epithelial Barrier and Transport 2012
    • Place of Presentation
      立命館大学(滋賀県)
    • Related Report
      2012 Research-status Report
  • [Presentation] 生体内リン代謝調節機構における唾液腺の関与2012

    • Author(s)
      向井朋
    • Organizer
      第66回日本栄養・食糧学会大会
    • Place of Presentation
      東北大学(宮城県)
    • Related Report
      2012 Research-status Report
  • [Presentation] 骨細胞と腎臓を結ぶリン代謝調節機序2012

    • Author(s)
      辰巳佐和子
    • Organizer
      第66回日本栄養・食糧学会大会
    • Place of Presentation
      東北大学(宮城県)
    • Related Report
      2012 Research-status Report
  • [Presentation] 慢性腎臓病患者におけるFGF23産生亢進の分子機能解析2012

    • Author(s)
      木戸慎介
    • Organizer
      第66回日本栄養・食糧学会大会
    • Place of Presentation
      東北大学(宮城県)
    • Related Report
      2012 Research-status Report
  • [Presentation] カドミウム汚染によるリン代謝異常・骨軟化症発症機序の検討2012

    • Author(s)
      木戸慎介
    • Organizer
      第30回日本骨代謝学会学術集会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Related Report
      2012 Research-status Report
  • [Presentation] 骨細胞死滅マウスのリン代謝異常について2012

    • Author(s)
      辰巳佐和子
    • Organizer
      第31回腎と骨代謝研究会学術集会
    • Place of Presentation
      経団連会館(東京都)
    • Related Report
      2012 Research-status Report
  • [Presentation] 腎臓切除後の低リン血症発症機構の解明2012

    • Author(s)
      野村憲吾
    • Organizer
      第45回日本栄養食糧学会 中国・四国支部大会
    • Place of Presentation
      愛媛大学(愛媛県)
    • Related Report
      2012 Research-status Report
  • [Presentation] 骨細胞とリン代謝2012

    • Author(s)
      釜谷 達哉
    • Organizer
      第15回日本病態栄養学会年次学術集会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Related Report
      2011 Research-status Report
  • [Presentation] カドミウム汚染によるリン代謝異常:骨軟化症発症機序の検討2012

    • Author(s)
      藤原 真理奈
    • Organizer
      第15回日本病態栄養学会年次学術集会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Related Report
      2011 Research-status Report
  • [Presentation] 糖尿病に併存する腎障害・骨障害の発症及び進展におけるFGF23の関与2012

    • Author(s)
      木戸 慎介
    • Organizer
      第15回日本病態栄養学会年次学術集会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Related Report
      2011 Research-status Report
  • [Presentation] リン代謝における腸管の役割2012

    • Author(s)
      宮本 賢一
    • Organizer
      第15回日本病態栄養学会年次学術集会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Related Report
      2011 Research-status Report
  • [Presentation] カドミウム汚染によるリン代謝異常;骨軟化症発症機序およびバイオマーカーの探索2012

    • Author(s)
      藤原 真里奈
    • Organizer
      第244回徳島医学会学術集会
    • Place of Presentation
      徳島大学(徳島県)
    • Related Report
      2011 Research-status Report
  • [Presentation] Post-Hepatectomy Hypophosphatemia in Rats2011

    • Author(s)
      Nomura K, Tatsumi S, Shiozaki Y, Yamaguchi S, Kamatani T, Segawa H, Kido S, Miyamoto K
    • Organizer
      Americal Society of Nephrology
    • Place of Presentation
      Pennsylvania Convention Center in Philadelphia,USA
    • Year and Date
      2011-11-12
    • Related Report
      2013 Final Research Report
  • [Presentation] Role of Sodium-Dependent Phosphate(Pi)Transporter(Npt2b)on Salivary Pi Secretion2011

    • Author(s)
      Segawa H, Mukai T, Ohnishi S, Sasaki S, Ohi A, Kuwahara S, Kido S, Tatsumi S, Ishikawa Y, Ueda O, Horiba N, Jishage K, Fukushima N, Miyamoto K
    • Organizer
      Americal Society of Nephrology
    • Place of Presentation
      Pennsylvania Convention Center in Philadelphia,USA
    • Year and Date
      2011-11-11
    • Related Report
      2013 Final Research Report
  • [Presentation] Molecular Consequences of the SLC34A3 Mutations of Hereditary Hypophosphatemic Rickets with Hypercalciuria(HHRH)2011

    • Author(s)
      Ohi A, Haito Sugino S, Ito M, Shiozaki Y, Nomura K,Kusaka Y, Sasaki S, Ohnishi S, Yamaguchi S, Kido S, Tatsumi S,Segawa H, Miyamoto K
    • Organizer
      Americal Society of Nephrology
    • Place of Presentation
      Pennsylvania Convention Center in Philadelphia,USA
    • Year and Date
      2011-11-10
    • Related Report
      2013 Final Research Report
  • [Presentation] Molecular Consequences of the SLC34A3 Mutations of Hereditary Hypophosphatemic Rickets with Hypercalciuria(HHRH)2011

    • Author(s)
      Akiko Ohi
    • Organizer
      American Society of Nephrology
    • Place of Presentation
      Pennsylvania Convention Center(Philadelphia)
    • Related Report
      2011 Research-status Report
  • [Presentation] Role of Sodium-Dependent Phosphate(Pi)Transporter(Npt2b)on Salivary Pi Secretion2011

    • Author(s)
      Hiroko Segawa
    • Organizer
      American Society of Nephrology
    • Place of Presentation
      Pennsylvania Convention Center(Philadelphia)
    • Related Report
      2011 Research-status Report
  • [Presentation] Post-Hepatectomy Hypophosphatemia in Rats2011

    • Author(s)
      Kengo Nomura
    • Organizer
      American Society of Nephrology
    • Place of Presentation
      Pennsylvania Convention Center(Philadelphia)
    • Related Report
      2011 Research-status Report
  • [Presentation] リン代謝におけるカルシウム受容体の役割2011

    • Author(s)
      辰巳 佐和子
    • Organizer
      第65回日本栄養・食糧学会大会
    • Place of Presentation
      お茶の水女子大学(東京都)
    • Related Report
      2011 Research-status Report
  • [Presentation] イタイイタイ病に見られる骨障害の発症・進展におけるFGF23の関与2011

    • Author(s)
      木戸 慎介
    • Organizer
      第65回日本栄養・食糧学会大会
    • Place of Presentation
      お茶の水女子大学(東京都)
    • Related Report
      2011 Research-status Report
  • [Presentation] 慢性腎臓病における食事リンによる腸管ペプチドトランスポーター調節2011

    • Author(s)
      瀬川 博子
    • Organizer
      第65回日本栄養・食糧学会大会
    • Place of Presentation
      お茶の水女子大学(東京都)
    • Related Report
      2011 Research-status Report
  • [Presentation] 高カルシウム尿を伴う遺伝性低リン血症性クル病の原因遺伝子リン酸トランスポーターNPT2cの変異体解析2011

    • Author(s)
      塩崎 雄治
    • Organizer
      第54回日本腎臓学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Related Report
      2011 Research-status Report
  • [Presentation] イタイイタイ病に見られる骨障害の発症・進展におけるFGF23の関与2011

    • Author(s)
      木戸 慎介
    • Organizer
      第29回日本骨代謝学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪府)
    • Related Report
      2011 Research-status Report
  • [Presentation] シナカルセト塩酸塩によるリン代謝2011

    • Author(s)
      辰巳 佐和子
    • Organizer
      第58回日本栄養改善学会学術総会
    • Place of Presentation
      広島国際会議場(広島県)
    • Related Report
      2011 Research-status Report
  • [Presentation] Hereditary hypophosphatemic rickets with hypercalciuria(HHRH)やFanconi’s syndromeにおける低リン血症の分子機構解明2011

    • Author(s)
      大西 沙織
    • Organizer
      第41回日本腎臓学会西部学術大会
    • Place of Presentation
      あわぎんホール(徳島県)
    • Related Report
      2011 Research-status Report
  • [Presentation] 糖尿病合併症発症におけるFGF23/Klothoの関与2011

    • Author(s)
      橋本 由衣
    • Organizer
      第44回日本栄養食糧学会中四国支部大会
    • Place of Presentation
      岡山県立大学(岡山県)
    • Related Report
      2011 Research-status Report
  • [Book] CKD-MBDハンドブック2nd Edition2013

    • Author(s)
      辰巳佐和子,野村憲吾,宮本賢一
    • Publisher
      日本メディカルセンター
    • Related Report
      2013 Final Research Report
  • [Book] NephrologyFrontier2013

    • Author(s)
      辰巳佐和子,藤田みゆき,野村憲吾,藤井理,宮本賢一
    • Publisher
      メディカルレビュー社(Vol.12, No.4)
    • Related Report
      2013 Final Research Report
  • [Book] CKD-MBDハンドブック2nd Edition2013

    • Author(s)
      辰巳佐和子,野村憲吾,宮本賢一.
    • Total Pages
      325
    • Publisher
      日本メディカルセンター
    • Related Report
      2013 Annual Research Report
  • [Book] NephrologyFrontier2013

    • Author(s)
      辰巳佐和子,藤田みゆき,野村憲吾,藤井理,宮本賢一.
    • Total Pages
      104
    • Publisher
      メディカルレビュー社
    • Related Report
      2013 Annual Research Report
  • [Book] 日本消化吸収学会雑誌2012

    • Author(s)
      桑原煩治,大井彰子,野村憲吾,辰巳佐和子,木戸慎介,瀬川博子,宮本賢一
    • Total Pages
      11
    • Publisher
      日本消化吸収学会(Vol.34 No.3)
    • Related Report
      2013 Final Research Report
  • [Book] 透析療法ネクストVIII~新時代の高リン血症治療~2012

    • Author(s)
      辰巳佐和子,木戸慎介,宮本賢一,伊藤美紀子
    • Publisher
      医学図書出版株式会社
    • Related Report
      2013 Final Research Report
  • [Book] CLINICAL CALCIUM 20122012

    • Author(s)
      瀬川博子,佐々木祥平,向井朋,真鍋舞,木戸慎介,辰巳佐和子,宮本賢一
    • Publisher
      医薬ジャーナル社(Vol.22 No.10)
    • Related Report
      2013 Final Research Report
  • [Book] CLINICAL CALCIUM 20122012

    • Author(s)
      辰巳佐和子,野村憲吾,宮川淳美,木戸慎介,瀬川博子
    • Publisher
      医薬ジャーナル社(Vol.22 No.10)
    • Related Report
      2013 Final Research Report
  • [Book] 循環器内科2012

    • Author(s)
      辰巳佐和子,野村憲吾,釜谷達哉,宮本賢一
    • Publisher
      科学評論社(Vol.71 No.3)
    • Related Report
      2013 Final Research Report
  • [Book] 透析療法ネクストVIII~新時代の高リン血症治療~2012

    • Author(s)
      辰巳佐和子
    • Publisher
      医学図書出版株式会社
    • Related Report
      2012 Research-status Report
  • [Book] 腎と骨代謝 2012Vol.25 No.12012

    • Author(s)
      木戸慎介
    • Publisher
      日本メディカルセンター
    • Related Report
      2012 Research-status Report
  • [Book] CLINICAL CALCIUM 2012 Vol.22 No.102012

    • Author(s)
      辰巳佐和子
    • Publisher
      医薬ジャーナル社
    • Related Report
      2012 Research-status Report
  • [Book] 腎不全医療における栄養管理の基礎知識2011

    • Author(s)
      伊藤美紀子,宮本賢一,辰巳佐和子
    • Publisher
      日本メディカルセンター
    • Related Report
      2013 Final Research Report
  • [Book] 腎不全医療におけうる栄養管理の基礎知識2011

    • Author(s)
      伊藤 美紀子 他
    • Publisher
      日本メディカルセンター
    • Related Report
      2011 Research-status Report

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Published: 2011-08-05   Modified: 2019-07-29  

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