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Shor-term and long-term effects of dietary intervention with Okinawan vegetable-rich traditional foods on clinical prameters including bood pressure.

Research Project

Project/Area Number 23591220
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Kidney internal medicine
Research InstitutionUniversity of the Ryukyus

Principal Investigator

OHYA Yusuke  琉球大学, 医学(系)研究科(研究院), 教授 (30240964)

Co-Investigator(Kenkyū-buntansha) TODORIKI Hidemi  琉球大学, 大学院医学研究科, 准教授 (60175479)
ISEKI Kunitoshi  琉球大学, 医学部附属病院, 准教授 (90193383)
Co-Investigator(Renkei-kenkyūsha) SASAKI Satoshi  東京大学, 医学研究科, 教授 (70275121)
Project Period (FY) 2011 – 2013
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2012: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords野菜 / 食事 / 沖縄 / 血圧 / 体重 / 食塩 / 高血圧
Research Abstract

Intervention of the Okinawan vegitable-rich traditional diet via the delivary of food (strong intervension) significantly decreased blood pressure and body weight. However, the analysis until now shows that the intervension via providing recipe of Okianwan traditional dishes and information of health promotion (weak intervention) did not significantly improved such parameters. Effects of strong intervention continued for one year with repeated information provision, however those of weak intervention did not change. These results suggest that the effects of food intervension is not large if its intensity is weak.

Report

(4 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Research-status Report
  • 2011 Research-status Report
  • Research Products

    (38 results)

All 2014 2013 2012 2011 Other

All Journal Article (23 results) (of which Peer Reviewed: 21 results) Presentation (13 results) Book (2 results)

  • [Journal Article] Hyperuricemia predicts future metabolic syndrome: a 4-year follow-up study of a large screened cohort in Okinawa, Japan.2014

    • Author(s)
      Nagahama K, Inoue T, Kohagura K, Ishihara A, Kinjo K, Ohya Y, Saito M, Tanaka R, Arishima S, Matsuzaki T, Ishihara S, Tokashiki T, Ohya Y.
    • Journal Title

      Hypertens Res.

      Volume: 37 Issue: 3 Pages: 232-238

    • DOI

      10.1038/hr.2013.137

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Interrelationship between brachial artery function and renal small artery sclerosis in chronic kidney disease2014

    • Author(s)
      Miyagi T, Kohagura K, Ishiki T, Kochi M, Kinjyo T, Kinjyo K, Maehara Y, Sakima A, Iseki K, Ohya Y
    • Journal Title

      Hypertens Res

      Volume: (Epub ahead of print) Issue: 9 Pages: 863-869

    • DOI

      10.1038/hr.2014.60

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Superoxide dismutase mimetic, tempol, aggravates renal injury in advanced-stage stroke-prone spontaneously hypertensive rats2014

    • Author(s)
      Sugama I, Kohagura K, Yamazato M, NakamuraT, Shinzato T, Ohya Y
    • Journal Title

      J Hypertens

      Volume: 32(3) Issue: 3 Pages: 534-41

    • DOI

      10.1097/hjh.0000000000000064

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Diuretics enhance effects of increased dose of candesartan on ambulatory blood pressure reduction in Japanese patients with uncontrolled hypertension treated with medium-dose angiotensin II receptor blockers.2014

    • Author(s)
      Sakima A, Kita T, Nakada S, Yokota N, Tamaki N, Etoh T, Shimokubo T, Kitamura T, Takishita S, Ohya Y.
    • Journal Title

      Clin Exp Hypertens.

      Volume: 36 Issue: 1 Pages: 40-45

    • DOI

      10.3109/10641963.2013.783052

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Association between the intima-media thickness of the brachiocephalic trunk and white matter hyperintensity in brain MRI.2013

    • Author(s)
      Isa K, Sakima A, Sakima H, Nakachi K, Kinjyo K, Ohya Y.
    • Journal Title

      Hypertens Res.

      Volume: 36 Issue: 11 Pages: 980-984

    • DOI

      10.1038/hr.2013.72

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Heart rate as a possible therapeutic guide for the prevention of cardiovascular disease (Review)2013

    • Author(s)
      Inoue T, Iseki K, Ohya Y
    • Journal Title

      Hypertens Res

      Volume: 36(10)(Epub 2013 Aug 22) Issue: 10 Pages: 838-44

    • DOI

      10.1038/hr.2013.98

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Trends in the incidence of stroke and cardiovascular risk factors on the isolated island of Okinawa : the Miyakojima study2013

    • Author(s)
      Sugama C, Isa K, Okumura K, Iseki K, Kinjo K, Ohya Y
    • Journal Title

      J Stroke Cerebrovasc Dis

      Volume: 22(7)

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hypertriglyceridemia accompanied by increased serum complement component 3 and proteinuria in non-nephrotic chronic kidney disease2013

    • Author(s)
      Kohagura K, Kochi M, Miyagi T, Kinjyo T, Maehara Y, Kinjyo K, Nagahama K, Sakima A, Iseki K, Ohya Y
    • Journal Title

      Clin Exp Nephrol

      Volume: (Epub ahead of print)

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios : KOCOA project2013

    • Author(s)
      Katsumata Y, Todoriki H, Higashiuesato Y, Yasura S, Ohya Y, Willcox DC, Dodge HH
    • Journal Title

      Journal of Alzheimer's Disease

      Volume: 34(1) Pages: 273-9

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] An association between uric acid levels and renal arteriolopathy in chronic kidney disease: a biopsy-based study.2013

    • Author(s)
      Kohagura K, Kochi M, Miyagi T, Kinjyo T, Maehara Y, Nagahama K, Sakima A, Iseki K, Ohya Y.
    • Journal Title

      Hypertens Res

      Volume: 36 Issue: 1 Pages: 43-49

    • DOI

      10.1038/hr.2012.135

    • NAID

      10031163284

    • Related Report
      2013 Annual Research Report 2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Very old adults with better memory function have higher low-density lipoprotein cholesterol levels and lower triglyceride to high-density lipoprotein cholesterol ratios: KOCOA project.2013

    • Author(s)
      Katsumata Y, Todoriki H, Higashiuesato Y, Yasura S, Ohya Y, Willcox DC, Dodge HH.
    • Journal Title

      Journal of Alzheimer’s Disease

      Volume: 34 Issue: 1 Pages: 273-279

    • DOI

      10.3233/jad-121138

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Trends in the Incidence of Stroke and Cardiovascular Risk Factors on the Isolated Island of Okinawa: The Miyakojima Study.2013

    • Author(s)
      Sugama C, Isa K, Okumura K, Iseki K, Kinjo K, Ohya Y.
    • Journal Title

      J Stroke Cerebrovasc Dis.

      Volume: in press

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Age- and sex-related effects on ankle-brachial index in a screened cohort of Japanese: the Okinawa Peripheral Arterial Disease Study (OPADS).2013

    • Author(s)
      Ishida A, Miyagi M, Kinjo K, Ohya Y.
    • Journal Title

      Eur J Prev Cardiol.

      Volume: in press

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] We need more evidence for antihypertensive treatment guided by home blood pressure.2012

    • Author(s)
      Sakima A, Ohya Y.
    • Journal Title

      Hypertens Res.

      Volume: 35 Issue: 11 Pages: 1048-50

    • DOI

      10.1038/hr.2012.153

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Transoral carotid ultrasonography using a micro convex probe with B-flow imaging for extracranial internal carotid artery dissection2012

    • Author(s)
      Sakima H, Isa K, Anegawa T, Kokuba K, Nakachi K, Goya Y, Tokashiki T, Ishiuchi S, Ohya Y
    • Journal Title

      J Stroke Cerebrovasc Dis

      Volume: 21(8)(Epub 2012 Jan 12) Issue: 8 Pages: 912.e5-912.e7

    • DOI

      10.1016/j.jstrokecerebrovasdis.2011.12.005

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Age- and sex-related effects on ankle-brachial index in a screened cohort of Japanese : the Okinawa Peripheral Arterial Disease Study (OPADS)2012

    • Author(s)
      Ishida A, Miyagi M, Kinjo K, Ohya Y
    • Journal Title

      Eur J Prev Cardiol

      Volume: (Epub ahead of print)

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] High glycated hemoglobin levels and intracranial artery stenosis are predictive factors for early motor worsening events in patients with penetrating artery infarction2012

    • Author(s)
      Isa K, Sakima H, Nakachi K, Kokuba K, Ishihara S, Tokashiki T, Ohya Y
    • Journal Title

      Eur Neurol

      Volume: 68(1)(Epub 2012 Jun) Pages: 16-9

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Early detection and prediction by biomarkers of acute kidney injury after cardiac surgery2012

    • Author(s)
      Kohagura K, Ohya Y
    • Journal Title

      Circ J

      Volume: 76(1)(Epub 2011 Dec 3. No abstract available) Pages: 53-4

    • NAID

      10030034106

    • Related Report
      2013 Final Research Report
  • [Journal Article] Metabolic syndrome and cognitive decline among the oldest old in Okinawa : in search of a mechanism. The KOCOA Project2012

    • Author(s)
      Katsumata Y, Todoriki H, Higashiuesato Y, Yasura S, Willcox DC, Ohya Y, Willcox BJ, Dodge HH
    • Journal Title

      J Gerontol A Biol Sci Med Sci

      Volume: 67(2) Issue: 2 Pages: 126-34

    • DOI

      10.1093/gerona/glr189

    • Related Report
      2013 Final Research Report 2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Beneficial Effect of Switching from a Combination of Angiotensin II Receptor Blockers other than Losartan and Thiazides to a Fixed Dose of Losartan/Hydrochlorothiazide on Uric Acid Metabolism in Hypertensive Patients2011

    • Author(s)
      Ohshiro K, Sakima A, Nakada S, Kohagura K, Yamazato M, Tana T, Ohya Y
    • Journal Title

      Clin Exp Hypertens

      Volume: 33(8)(Epub 2011 Sep 29) Issue: 8 Pages: 565-70

    • DOI

      10.3109/10641963.2011.577487

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] A strategy for obesity control : repetition is the key2011

    • Author(s)
      Ohya Y
    • Journal Title

      Hypertens Res

      Volume: 34(5)(Epub 2011 Mar 10. No abstract available) Pages: 548-548

    • NAID

      10031163215

    • Related Report
      2013 Final Research Report
  • [Journal Article] 脳卒中再発予防と地域連携に関するアンケート―県内かかりつけ医からの集計―2011

    • Author(s)
      伊佐勝憲,大屋祐輔
    • Journal Title

      沖縄医学会雑誌

      Volume: 50 Pages: 20-22

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Recurrent embolic stroke due to nonbacterial thrombotic endocarditis followed by transesophageal echocardiography2011

    • Author(s)
      Sakima H, Isa K, Kokuba K, Nakachi K, Ikemiyagi H, Shiroma K, Ishihara S, Tokashiki T,; Yasu T. Ohya Y
    • Journal Title

      Arch Neurol

      Volume: 68(12)(No abstract available) Issue: 12 Pages: 1604-1605

    • DOI

      10.1001/archneurol.2011.687

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Presentation] 沖縄の健康長寿復活に向けた健康行動実践モデル実証事業:ゆい健康プロジェクト-研究・調査デザイン-2013

    • Author(s)
      崎間敦,等々力英美,白井こころ,高倉実,金城昇,小浜敬子,安仁屋文香,武村克哉,奥村耕一郎,大屋祐輔
    • Organizer
      第45回沖縄県公衆衛生学会
    • Place of Presentation
      那覇市
    • Year and Date
      2013-11-01
    • Related Report
      2013 Final Research Report
  • [Presentation] 特定健診からみた沖縄県の健康課題2013

    • Author(s)
      安仁屋文香,小浜敬子,崎間敦,高倉実,白井こころ,金城昇,等々力英美,武村克哉,奥村耕一郎,大屋祐輔
    • Organizer
      第45回沖縄県公衆衛生学会
    • Place of Presentation
      那覇市
    • Year and Date
      2013-11-01
    • Related Report
      2013 Final Research Report
  • [Presentation] 沖縄県民における肥満・生活習慣病の経年推移-平成20年および平成22年の特定健診結果から-2013

    • Author(s)
      小浜敬子,安仁屋文香,高倉実,崎間敦,白井こころ,金城昇,等々力英美,武村克哉,奥村耕一郎,大屋祐輔
    • Organizer
      第45回沖縄県公衆衛生学会
    • Place of Presentation
      那覇市
    • Year and Date
      2013-11-01
    • Related Report
      2013 Final Research Report
  • [Presentation] 沖縄県の高齢者にみる社会経済的背景と保健行動・生活習慣との関係:JAGES STUDY OKINAWA2013

    • Author(s)
      白井こころ,小浜敬子,安仁屋文香,大屋祐輔,等々力英美,金城昇,高倉実,崎間敦,奥村耕一郎,武村克哉
    • Organizer
      第45回沖縄県公衆衛生学会
    • Place of Presentation
      那覇市
    • Year and Date
      2013-11-01
    • Related Report
      2013 Final Research Report
  • [Presentation] 肥満および飲酒習慣が若年者高血圧へおよぼす影響:職域健診受診者における断面研究2013

    • Author(s)
      崎間敦,金城幸善,大屋祐輔
    • Organizer
      第36回日本高血圧学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2013-10-25
    • Related Report
      2013 Final Research Report
  • [Presentation] 沖縄の若年者世代における減塩対策の重要性‐時系列データによる検討‐2012

    • Author(s)
      等々力英美,崎間敦
    • Organizer
      第44回沖縄県公衆衛生学会
    • Place of Presentation
      那覇市
    • Year and Date
      2012-11-09
    • Related Report
      2013 Final Research Report
  • [Presentation] 午前中の随時尿による1日推定食塩摂取量は収縮期血圧と正相関している高血圧および慢性腎臓病外来患者での検討2012

    • Author(s)
      新垣友加里,崎間敦,等々力英美,古波蔵健太郎,仲田清剛,山里正演,石田明夫,安隆則,大屋祐輔
    • Organizer
      第35回日本高血圧学会総会
    • Place of Presentation
      名古屋市
    • Year and Date
      2012-10-21
    • Related Report
      2013 Final Research Report
  • [Presentation] 高血圧および慢性腎臓病患者の1日推定食塩摂取量における年齢とbody mass indexの影響についての検討2012

    • Author(s)
      新垣友加里,崎間敦,古波蔵健太郎,仲田清剛,山里正演,石田明夫,安隆則,大屋祐輔,等々力英美
    • Organizer
      第1回臨床高血圧フォーラム
    • Place of Presentation
      豊中市
    • Year and Date
      2012-05-13
    • Related Report
      2013 Final Research Report
  • [Presentation] 短期的食事介入に継続した長期的情報介入による介入効果は持続するか?-血圧および体重変動:チャンプルースタディ4の結果より-2011

    • Author(s)
      等々力英美,大屋祐輔,佐々木敏
    • Organizer
      沖縄県公衆衛生学会
    • Place of Presentation
      那覇市
    • Year and Date
      2011-11-11
    • Related Report
      2013 Final Research Report
  • [Presentation] 沖縄地域におけるソーシャル・キャピタル(SC)と主観的健康状態との関係2011

    • Author(s)
      白井こころ,等々力英美,菖蒲川由郷, Ichiro Kawachi,三澤仁平,近藤克則
    • Organizer
      沖縄県公衆衛生学会
    • Place of Presentation
      那覇市
    • Year and Date
      2011-11-11
    • Related Report
      2013 Final Research Report
  • [Presentation] 栄養指導の取り組みと成果パターン食の介入は有効か?チャンプルースタディーの経験より2011

    • Author(s)
      大屋祐輔,等々力英美
    • Organizer
      日本高血圧学会総会
    • Place of Presentation
      栃木県
    • Year and Date
      2011-10-21
    • Related Report
      2013 Final Research Report
  • [Presentation] パターン食の介入は有効か?チャンプルー研究の経験より

    • Author(s)
      大屋祐輔、等々力英美
    • Organizer
      第34回日本高血圧学会
    • Place of Presentation
      栃木総合文化センター・宇都宮東武ホテルグランデ
    • Related Report
      2011 Research-status Report
  • [Presentation] 高血圧および慢性腎臓病患者の1日推定食塩摂取量の実態とその関連因子について

    • Author(s)
      崎間敦、大屋祐輔ほか
    • Organizer
      第34回日本高血圧学会
    • Place of Presentation
      栃木総合文化センター・宇都宮東武ホテルグランデ
    • Related Report
      2011 Research-status Report
  • [Book] ソーシャルキャピタルと地域の力2013

    • Author(s)
      イチロー・カワチ、等々力英美(編)(大屋は分担執筆)
    • Publisher
      日本評論社
    • Related Report
      2013 Final Research Report
  • [Book] ソーシャル・キャピタルと地域の力2013

    • Author(s)
      イチロー・カワチ+等々力英美(編)
    • Total Pages
      239
    • Publisher
      日本評論社
    • Related Report
      2013 Annual Research Report

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Published: 2011-08-05   Modified: 2019-07-29  

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