| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
Although amyotrophic lateral sclerosis (ALS) sometimes accompanies frontotemporal dementia, it is not easy to estimate cognitive impairment clearly. In this study, self-rating scale for anosognosia and evaluation of writing errors were found important to detect subclinical stage of dementia. As regard to writing, double dissociation between kana and kanji in writing was observed; errors of kana were predominated in general, but errors of kanji were predominated in some cases. Although progression of brain atrophy was different across patients, distribution and progression rate of frontotemporal atrophy were associated with the above clinical characteristics.
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